Facilitators and Barriers of Medication Adherence in Pediatric Liver and Kidney Transplant Recipients: A Mixed-Methods Study

2014 ◽  
Vol 24 (4) ◽  
pp. 311-321 ◽  
Author(s):  
Anouck Claes ◽  
Anneloes Decorte ◽  
Elena Levtchenko ◽  
Noel Knops ◽  
Fabienne Dobbels
Keyword(s):  
Mixed Methods ◽  
Medication Adherence ◽  
Kidney Transplant ◽  
Mixed Methods Study ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Pediatric Liver ◽  
Liver And Kidney ◽  
Facilitators And Barriers

scholarly journals Bacterial and fungal bloodstream infections in pediatric liver and kidney transplant recipients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dina Leth Møller ◽  
Søren Schwartz Sørensen ◽  
Neval Ete Wareham ◽  
Omid Rezahosseini ◽  
Andreas Dehlbæk Knudsen ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Bloodstream Infections ◽  
Incidence Rates ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Post Transplantation ◽  
Pediatric Liver ◽  
Resistance Patterns ◽  
Liver And Kidney ◽  
Liver Transplant Recipients

Abstract Background Bacterial and fungal bloodstream infections (BSI) are common after pediatric liver and kidney transplantations and associated with morbidity and mortality. However, knowledge about incidence rates, pathogen composition, and resistance patterns is limited. We aimed to describe the pattern of bacterial and fungal BSI in a cohort of pediatric liver and kidney transplant recipients. Methods A prospective study of 85 pediatric liver and kidney transplant recipients transplanted from 2010 to 2017 with a total of 390 person-years of follow-up. Clinical characteristics and BSI were retrieved from national registries assuring nationwide follow-up for at least 1 year. BSI incidence rates and pathogen composition were investigated and stratified by the time post-transplantation and type of transplanted organ. Results A total of 29 BSI were observed within the first 5 years post-transplantation with 16 different pathogens. The overall incidence rate of first BSI was 1.91 per 100 recipients per month (95% CI, 1.1–3.1) in the first year post-transplantation. The most common pathogens were Enterococcus faecium, Candida albicans, Escherichia coli, and Klebsiella pneumoniae. The pathogen composition depended on the transplanted organ with a higher proportion of BSI with Enterobacterales in kidney transplant recipients than in liver transplant recipients (67% vs. 20%, p = 0.03), while multiple pathogens were detected in the liver transplant recipients. Conclusions BSI were common in pediatric liver and kidney transplant recipients and the pathogen composition differed between liver and kidney transplant recipients. Guidelines for empiric antibiotic therapy should consider the type of transplanted organ as well as the local resistance patterns.

Bacterial and Fungal Bloodstream Infections in Pediatric Liver and Kidney Transplant Recipients

2020 ◽  
Author(s):  
Dina Møller ◽  
Søren Sørensen ◽  
Neval Wareham ◽  
Omid Rezahosseini ◽  
Andreas Knudsen ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Bloodstream Infections ◽  
Incidence Rates ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Post Transplantation ◽  
Pediatric Liver ◽  
Resistance Patterns ◽  
Liver And Kidney ◽  
Liver Transplant Recipients

Abstract Background Bacterial and fungal bloodstream infections (BSI) are common after pediatric liver and kidney transplantations and associated with morbidity and mortality. However, knowledge about incidence rates, pathogen composition, and resistance patterns is limited. We aimed to describe the pattern of bacterial and fungal BSI in a cohort of pediatric liver and kidney transplant recipients.Methods A prospective study of 85 pediatric liver and kidney transplant recipients transplanted from 2010 to 2017 with a total of 390 person-years of follow-up. Clinical characteristics and BSI were retrieved from national registries assuring nationwide follow-up for at least one year. BSI incidence rates and pathogen composition were investigated and stratified by the time post-transplantation and type of transplanted organ. Results A total of 29 BSI were observed within the first 5 years post-transplantation with 16 different pathogens. The overall incidence rate of first BSI was 1.91 per 100 recipients per month (95% CI, 1.1-3.1) in the first-year post-transplantation. The most common pathogens were Enterococcus faecium, Candida albicans, Escherichia coli, and Klebsiella pneumoniae. The pathogen composition depended on the transplanted organ with a higher proportion of BSI with Enterobacterales in kidney transplant recipients than in liver transplant recipients (67% vs. 20%, P = 0.03), while multiple pathogens were detected in the liver transplant recipients.Conclusions BSI were common in pediatric liver and kidney transplant recipients and the pathogen composition differed between liver and kidney transplant recipients. Guidelines for empiric antibiotic therapy should consider the type of transplanted organ as well as the local resistance patterns.

Tu1125 Eosinophilic Gastrointestinal Disease in Pediatric Liver and Kidney Transplant Recipients

2015 ◽  
Vol 148 (4) ◽  
pp. S-794
Author(s):  
Katie Amsden ◽  
Saeed Mohammad ◽  
Jonathan W. Bush ◽  
Hector Melin-Aldana ◽  
Nicoleta Arva ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Gastrointestinal Disease ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Pediatric Liver ◽  
Liver And Kidney

ALLOREACTIVITY IN LIVER AND KIDNEY TRANSPLANT RECIPIENTS

2008 ◽  
Vol 86 (Supplement) ◽  
pp. 403-404
Author(s):  
M Lindemann ◽  
H Klinkenbusch ◽  
C Saure ◽  
O Witzke ◽  
C Valentin-Gamazo ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Liver And Kidney
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