Carbon dioxide insufflation versus air insufflation during endoscopic retrograde cholangiopancreatography: a meta-analysis

2013 ◽  
Vol 3 (1) ◽  
pp. 37 ◽  
Author(s):  
Jun Wu ◽  
Keyword(s):  
Carbon Dioxide ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Meta Analysis ◽  
Carbon Dioxide Insufflation ◽  
Endoscopic Retrograde ◽  
Air Insufflation

Sa1730 Comparisons Between Carbon Dioxide Insufflation and Air Insufflation in Colonoscopy: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 85 (5) ◽  
pp. AB258
Author(s):  
Nádia Korkischko ◽  
Wanderlei M. Bernardo ◽  
Marina L. Passos ◽  
Priscilla C. Bonifacio ◽  
Mileine V. de Matos ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Systematic Review ◽  
Meta Analysis ◽  
Carbon Dioxide Insufflation ◽  
Air Insufflation

scholarly journals Efficacy and safety of carbon dioxide insufflation versus air insufflation during endoscopic retrograde cholangiopancreatography in randomized controlled trials: a systematic review and meta-analysis

2019 ◽  
Vol 07 (04) ◽  
pp. E487-E497 ◽  
Author(s):  
Marina Passos ◽  
Igor Ribeiro ◽  
Diogo de Moura ◽  
Nádia Korkischko ◽  
Gustavo Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Abdominal Distension ◽  
Ambient Air ◽  
Controlled Trials ◽  
Efficacy And Safety ◽  
Carbon Dioxide Insufflation ◽  
Endoscopic Retrograde ◽  
Randomized Controlled ◽  
Air Insufflation

Abstract Background and study aims Ambient air is the most commonly used gas for insufflation in endoscopic procedures worldwide. However, prolonged absorption of air during endoscopic examinations may cause pain and abdominal distension. Carbon dioxide insufflation (CO2i) has been increasingly used as an alternative to ambient air insufflation (AAi) in many endoscopic procedures due to its fast diffusion properties and less abdominal distention and pain. For endoscopic retrograde cholangiopancreatography (ERCP), use of CO2 for insufflation is adequate because this procedure is complex and prolonged. Some randomized controlled trials (RCTs) have evaluated the efficacy and safety of CO2 as an insufflation method during ERCP but presented conflicting results. This systematic review and meta-analysis with only RCTs evaluated the efficacy and safety of CO2i versus AAi during ERCP. Methods A literature search was performed using online databases with no restriction regarding idiom or year of publication. Data were extracted by two authors according to a predefined data extraction form. Outcomes evaluated were abdominal pain and distension, complications, procedure duration, and CO2 levels. Results Eight studies (919 patients) were included. Significant results favoring CO2i were less abdominal distension after 1 h (MD: −1.41 [−1.81; −1.0], 95 % CI, I² = 15 %, P < 0.00001) and less abdominal pain after 1 h (MD: −23.80 [−27.50; −20.10], 95 %CI, I² = 9 %, P < 0.00001) and after 6 h (MD: −7.00 [−8.66; −5.33]; 95 % CI, I² = 0 %, P < 0.00001). Conclusion Use of CO2i instead of AAi during ERCP is safe and associated with less abdominal distension and pain after the procedure.

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