scholarly journals Novel and potent gastrin and brain cholecystokinin antagonists from Streptomyces olivaceus. Taxonomy, fermentation, isolation, chemical conversions, and physico-chemical and biochemical properties.

1991 ◽  
Vol 44 (6) ◽  
pp. 613-625 ◽  
Author(s):  
Y. K. TONY LAM ◽  
DEBRA BOGEN ◽  
RAYMOND S. CHANG ◽  
KRISTINE A. FAUST ◽  
OTTO D. HENSENS ◽  
...  
2015 ◽  
Vol 2 (3) ◽  
pp. 395-410 ◽  
Author(s):  
Shah Md Yusuf Ali ◽  
Md Ahiduzzaman ◽  
Sharmin Akhter ◽  
M Abdul Matin Biswas ◽  
Nafis Iqbal ◽  
...  

Pineapple is considered as one of the most wanted tropical fruits and it is widely taken for fresh consumption as well as their flesh and juice are used for preparation of different product in Agro-processing industries. For such industrial processes, it is important to know the information of characteristics changes of pineapple during day after storage. Four varieties of pineapple were collected from different areas of Bangladesh named Honey Queen (H.Q), Giant Kew (G.K), Asshini and Ghorasal. Some Physico-chemical properties (weight loss, moisture content, ash and edible portion, pH, TSS, titrable acidity (TA), total sugar, reducing sugar) biochemical properties (ascorbic acid) and sensorial attributes (color, odor, firmness, appearances, sweetness and overall acceptability) of pineapple juice were studied during day after storage. This study examined the Comparison of different varieties of pineapple fruit characteristics and sensory quality of the pineapple fruits during storage. It was shown that there was a significant changes between the storage periods in relation to different varieties of fruits. The firmness of pineapple fruits were in outside and inside to be 0.21 to 0.27 N/m2 and 0.06 to 0.10 N/m2, respectively. The pH values of different varieties were found to be in the range of 4.30 to 4.36. The highest and lowest sweetness index were estimated to be 36.30 and 22.15 for Honey Queen and Asshini respectively. The highest and lowest magnitude of sugar contents of four pineapple varieties were found to be in the range of 14.16 to 15.8 mg/100g.The average TSS values were found to be 15.12%, 12.33%, 13.14% and 12.95% for H.Q., G.K., Asshini and Ghorashal, respectively. The comparative study indicated the characteristics of different varieties of pineapple changes during after storage.Res. Agric., Livest. Fish.2(3): 395-410, December 2015


2014 ◽  
Vol 56 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Ewa Błońska ◽  
Jarosław Lasota

Abstract The aim of this study was to assess the possibility of using biological and biochemical parameters in the evaluation of forest soil quality and changes caused by land use. The study attempted to determine a relationship between the enzymatic activity of soil, the number of earthworms and soil physico-chemical properties. The study was carried out in central Poland in adjoining Forest Districts (Przedbórz and Smardzewice). In soil samples taken from 12 research plots, basic physico-chemical properties, enzyme activity (dehydrogenase, urease) and density and biomass of earthworms were examined. Enzyme activity showed a large diversity within the forest site types studied. The correlations between the activity of the enzymes studied and C/N ratio indicated considerable importance of these enzymes in metabolism of essential elements of organic matter of forest soils. Urease and dehydrogenase activity and earthworm number showed susceptibility to soil pH, which confirmed relationships between enzyme activity and abundance of earthworms and soil pH in H2O and KCl.


Author(s):  
Jacek Jemielity ◽  
Joanna Zuberek ◽  
Janusz Stępiński ◽  
Magdalena Lewdorowicz ◽  
Anna Niedzwiecka ◽  
...  

Biotechnology ◽  
2019 ◽  
pp. 2054-2089
Author(s):  
Helina Patel ◽  
Akshaya Gupte

The search for cost-effective and environmental benign practices for the production of bioactive compounds has gained considerable attention since last decade, due to increasing demand of eco-friendly processes. Many industries have started adopting routes for the development of green chemistry by employing enzymatic approaches to overcome the limitations of physico-chemical methods and environmental concerns. Laccase is one such enzyme which has gained considerable attention in recent years as a biocatalyst in organic synthesis. Laccases possess versatile biochemical properties and the reactions catalyzed by laccase require only molecular oxygen with concomitant release of water as a byproduct. They have been widely used for reactions such as dimerization, polymerization, coupling, and grafting reactions and for antibiotic modifications. This chapter summarizes the advances that have been made in developing technologies based on laccase mediated reactions in the field of medicine, agriculture, food, and pharmaceuticals.


2002 ◽  
Vol 363 (3) ◽  
pp. 609-617 ◽  
Author(s):  
Olli H. LAITINEN ◽  
Vesa P. HYTÖNEN ◽  
Mervi K. AHLROTH ◽  
Olli T. PENTIKÄINEN ◽  
Ciara GALLAGHER ◽  
...  

Chicken avidin and bacterial streptavidin are proteins familiar from their use in various (strept)avidin—biotin technological applications. Avidin binds the vitamin biotin with the highest affinity known for non-covalent interactions found in nature. The gene encoding avidin (AVD) has homologues in chicken, named avidin-related genes (AVRs). In the present study we used the AVR genes to produce recombinant AVR proteins (AVRs 1, 2, 3, 4/5, 6 and 7) in insect cell cultures and characterized their biotin-binding affinity and biochemical properties. Amino acid sequence analysis and molecular modelling were also used to predict and explain the properties of the AVRs. We found that the AVR proteins are very similar to avidin, both structurally and functionally. Despite the numerous amino acid substitutions in the subunit interface regions, the AVRs form extremely stable tetramers similar to those of avidin. Differences were found in some physico-chemical properties of the AVRs as compared with avidin, including lowered pI, increased glycosylation and, most notably, reversible biotin binding for two AVRs (AVR1 and AVR2). Molecular modelling showed how the replacement Lys111→isoleucine in AVR2 alters the shape of the biotin-binding pocket and thus results in reversible binding. Both modelling and biochemical analyses showed that disulphide bonds can form and link monomers in AVR4/5, a property not found in avidin. These, together with the other properties of the AVRs described in the present paper, may offer advantages over avidin and streptavidin, making the AVRs applicable for improved avidin—biotin technological applications.


2019 ◽  
Vol 242 ◽  
pp. 94-105 ◽  
Author(s):  
Bal Kumari Sharma Khanal ◽  
Chrysanthea Budiman ◽  
Mark P. Hodson ◽  
Manuel R.R. Plan ◽  
Sangeeta Prakash ◽  
...  

2017 ◽  
Vol 72 ◽  
pp. 29-35 ◽  
Author(s):  
Jorge M.S. Pinto ◽  
Sérgio Sousa ◽  
Dina M. Rodrigues ◽  
Francisco X. Malcata ◽  
Armando C. Duarte ◽  
...  

Pharmacology ◽  
1964 ◽  
Vol 11 (1) ◽  
pp. 27-37 ◽  
Author(s):  
S. Casadio ◽  
G. Coppi ◽  
P. Fresia

2011 ◽  
Vol 6 (4) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Erminio Murano ◽  
Danilo Perin ◽  
Riaz Khan ◽  
Massimo Bergamin

Hyaluronan (hyaluronic acid) is a naturally occurring polysaccharide of a linear repeating disaccharide unit consisting of β-(1→4)-linked D-glucopyranuronic acid and β-(1→3)-linked 2-acetamido-2-deoxy-D-glucopyranose, which is present in extracellular matrices, the synovial fluid of joints, and scaffolding that comprises cartilage. In its mechanism of synthesis, its size, and its physico-chemical properties, hyaluronan is unique amongst other glycosaminoglycans. The network-forming, viscoelastic and its charge characteristics are important to many biochemical properties of living tissues. It is an important pericellular and cell surface constituent; its interaction with other macromolecules such as proteins, participates in regulating cell behavior during numerous morphogenic, restorative, and pathological processes in the body. The knowledge of HA in diseases such as various forms of cancers, arthritis and osteoporosis has led to new impetus in research and development in the preparation of biomaterials for surgical implants and drug conjugates for targeted delivery. A concise and focused review on hyaluronan is timely. This review will cover the following important aspects of hyaluronan: (i) biological functions and synthesis in nature; (ii) current industrial production and potential biosynthetic processes of hyaluronan; (iii) chemical modifications of hyaluronan leading to products of commercial significance; and (iv) and the global market position and manufacturers of hyaluronan.


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