scholarly journals Supramolecular Nanomachines as Stimuli-Responsive Gatekeepers on Mesoporous Silica Nanoparticles for Antibiotic and Cancer Drug Delivery

Theranostics ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 3341-3364 ◽  
Author(s):  
Chi-An Cheng ◽  
Tian Deng ◽  
Fang-Chu Lin ◽  
Yao Cai ◽  
Jeffrey I. Zink
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Cancer Drug ◽  
Stimuli Responsive ◽  
Cancer Drug Delivery

99mTc-conjugated manganese-based mesoporous silica nanoparticles for SPECT, pH-responsive MRI and anti-cancer drug delivery

Nanoscale ◽  
2016 ◽  
Vol 8 (47) ◽  
pp. 19573-19580 ◽  
Author(s):  
Hongbo Gao ◽  
Xiaohang Liu ◽  
Wei Tang ◽  
Dechao Niu ◽  
Bingni Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Cancer Drug ◽  
Ph Responsive ◽  
Anti Cancer ◽  
Cancer Drug Delivery

scholarly journals Mesoporous Silica Nanoparticles: Their Projection in Nanomedicine

2012 ◽  
Vol 2012 ◽  
pp. 1-20 ◽  
Author(s):  
María Vallet-Regí
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Surrounding Medium ◽  
Stimuli Responsive ◽  
Guest Molecules ◽  
Different Types ◽  
Potential Applications ◽  
Inorganic Nanomaterials

Mesoporous silica nanoparticles are receiving growing attention by the scientific biomedical community. Among the different types of inorganic nanomaterials, mesoporous silica nanoparticles have emerged as promising multifunctional platforms for nanomedicine. Since their introduction in the drug delivery landscape in 2001, mesoporous materials for drug delivery are receiving growing scientific interest for their potential applications in the biotechnology and nanomedicine fields. The ceramic matrix efficiently protects entrapped guest molecules against enzymatic degradation or denaturation induced by pH and temperature as no swelling or porosity changes take place as a response to variations in the surrounding medium. It is possible to load huge amounts of cargo into the mesopore voids and capping the pore entrances with different nanogates. The application of a stimulus provokes the nanocap removal and triggers the departure of the cargo. This strategy permits the design of stimuli-responsive drug delivery nanodevices.

scholarly journals Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update

2019 ◽  
Vol 16 (4) ◽  
pp. 415-439 ◽  
Author(s):  
Rafael R. Castillo ◽  
Daniel Lozano ◽  
Blanca González ◽  
Miguel Manzano ◽  
Isabel Izquierdo-Barba ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Stimuli Responsive

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

scholarly journals Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery

Nanoscale ◽  
2015 ◽  
Vol 7 (16) ◽  
pp. 7178-7183 ◽  
Author(s):  
Isurika R. Fernando ◽  
Daniel P. Ferris ◽  
Marco Frasconi ◽  
Dmitry Malin ◽  
Elena Strekalova ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Amino Ester ◽  
Stimuli Responsive ◽  
Ph Responsive

Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved.

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

2017 ◽  
Vol 6 (13) ◽  
pp. 1700012 ◽  
Author(s):  
Arne Kienzle ◽  
Sven Kurch ◽  
Janine Schlöder ◽  
Carsten Berges ◽  
Robert Ose ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tnf Alpha ◽  
Stimuli Responsive
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