scholarly journals Hypoxia-triggered single molecule probe for high-contrast NIR II/PA tumor imaging and robust photothermal therapy

Theranostics ◽  
2018 ◽  
Vol 8 (21) ◽  
pp. 6025-6034 ◽  
Author(s):  
Xiaoqing Meng ◽  
Jiali Zhang ◽  
Zhihong Sun ◽  
Lihua Zhou ◽  
Guanjun Deng ◽  
...  
Keyword(s):  
Single Molecule ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
High Contrast

scholarly journals Multiplexed Liquid Biopsy and Tumor Imaging Using Surface-Enhanced Raman Scattering

Biosensors ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 449
Author(s):  
Francesco Dell’Olio
Keyword(s):  
Raman Scattering ◽  
Single Molecule ◽  
Liquid Biopsy ◽  
Tumor Imaging ◽  
Surface Enhanced Raman Scattering ◽  
Detection Sensitivity ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

The recent improvements in diagnosis enabled by advances in liquid biopsy and oncological imaging significantly better cancer care. Both these complementary approaches, which are used for early tumor detection, characterization, and monitoring, can benefit from applying techniques based on surface-enhanced Raman scattering (SERS). With a detection sensitivity at the single-molecule level, SERS spectroscopy is widely used in cell and molecular biology, and its capability for the in vitro detection of several types of cancer biomarkers is well established. In the last few years, several intriguing SERS applications have emerged, including in vivo imaging for tumor targeting and the monitoring of drug release. In this paper, selected recent developments and trends in SERS applications in the field of liquid biopsy and tumor imaging are critically reviewed, with a special emphasis on results that demonstrate the clinical utility of SERS.

Polypyrrole-encapsulated iron tungstate nanocomposites: a versatile platform for multimodal tumor imaging and photothermal therapy

Nanoscale ◽  
2016 ◽  
Vol 8 (26) ◽  
pp. 12917-12928 ◽  
Author(s):  
Zhiyin Xiao ◽  
Chen Peng ◽  
Xiaohong Jiang ◽  
Yuxuan Peng ◽  
Xiaojuan Huang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Tumor Imaging

Glutathione-Responsive Self-Assembled Magnetic Gold Nanowreath for Enhanced Tumor Imaging and Imaging-Guided Photothermal Therapy

ACS Nano ◽  
2018 ◽  
Vol 12 (8) ◽  
pp. 8129-8137 ◽  
Author(s):  
Yijing Liu ◽  
Zhen Yang ◽  
Xiaolin Huang ◽  
Guocan Yu ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Self Assembled

Acid-Triggered in Situ Aggregation of Gold Nanoparticles for Multimodal Tumor Imaging and Photothermal Therapy

2019 ◽  
Vol 5 (3) ◽  
pp. 1589-1601 ◽  
Author(s):  
Yumin Zhang ◽  
Jinglin Chang ◽  
Fan Huang ◽  
Lijun Yang ◽  
Chunhua Ren ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Photothermal Therapy ◽  
Tumor Imaging

A Single Molecule Drug Targeting Photosensitizer for Enhanced Breast Cancer Photothermal Therapy

Small ◽  
2020 ◽  
Vol 16 (18) ◽  
pp. 1907677 ◽  
Author(s):  
Yang Zou ◽  
Mingle Li ◽  
Tao Xiong ◽  
Xueze Zhao ◽  
Jianjun Du ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Molecule ◽  
Drug Targeting ◽  
Photothermal Therapy

scholarly journals NIMG-76. SURFACE-ENHANCED RAMAN SPECTROSCOPY (SERS) FOR INTRAOPERATIVE BRAIN TUMOR IMAGING AND PHOTOTHERMAL THERAPY

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi159-vi159 ◽  
Author(s):  
Hamed Arami ◽  
Edwin Chang ◽  
Chirag B Patel ◽  
Steven James Madsen ◽  
Ryan Miller Davis ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Brain Tumor ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Pillar[5]arene-Modified Gold Nanorods as Nanocarriers for Multi-Modal Imaging-Guided Synergistic Photodynamic-Photothermal Therapy

2020 ◽  
Author(s):  
Nan Song ◽  
Zhijun Zhang ◽  
Peiying Liu ◽  
Dihua Dai ◽  
Chao Chen ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
High Performance ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Functional Materials ◽  
Ros Generation ◽  
Cancer Therapies ◽  
New Strategy

Supramolecular approaches have opened up vast possibilities in the construction of versatile functional materials, especially those with stimuli-responsiveness and integrated functionalities of multi-modal diagnosis and synergistic therapeutics. In this study, a hybrid theranostic nanosystem named TTPY-PyÌCP5@AuNR is constructed via facile host-guest interactions, where TTPY-Py is a photosensitizer with aggregation-induced emission and CP5@AuNR represents the carboxylatopillar[5]arene (CP5)-modified Au nanorods. TTPY-PyÌCP5@AuNR integrates the respective advantages of TTPY-Py and CP5@AuNR such as the high performance of reactive oxygen species (ROS) generation and photothermal conversion, and meanwhile shows fluorescence responses to both temperature and pH stimuli due to the non-covalent interactions. The successful modification of CP5 macrocycles on AuNRs surfaces can eliminate the cytotoxicity of AuNRs and enable them to serve as the nanocarrier of TTPY-Py for further theranostic application. Significantly, both in vitro and in vivo evaluations demonstrate that this supramolecular nanotheranostic system possesses multiple phototheranostic modalities including intensive fluorescence imaging (FLI), photoacoustic imaging (PAI), efficient photodynamic therapy (PDT), and photothermal therapy (PTT), indicating its great potentials for FLI-PAI imaging-guided synergistic PDT-PTT therapy. Besides, TTPY-Py can be released from the nanocarriers upon activating by the acidic environment of lysosomes and then specifically light up mitochondria. This study brings up a new strategy into the design of versatile nanotheranostics for accurate tumor imaging and cancer therapies.

scholarly journals A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy

Theranostics ◽  
2015 ◽  
Vol 5 (9) ◽  
pp. 946-960 ◽  
Author(s):  
Yang Liu ◽  
Jeffrey R. Ashton ◽  
Everett J. Moding ◽  
Hsiangkuo Yuan ◽  
Janna K. Register ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Gold Nanostar

Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy

2020 ◽  
Vol 8 (22) ◽  
pp. 4738-4747 ◽  
Author(s):  
Xue Zhang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Tumor Diagnosis ◽  
Diagnosis And Treatment ◽  
Recent Advances

This review summarizes the recent advances of tumor microenvironment-activated NIR-II agents for tumor diagnosis and treatment, including smart NIR-II fluorescence imaging, photoacoustic imaging, photothermal therapy and photodynamic therapy.

Functionalized theranostic nanocarriers with bio-inspired polydopamine for tumor imaging and chemo-photothermal therapy

2019 ◽  
Vol 309 ◽  
pp. 203-219 ◽  
Author(s):  
Mehdi Farokhi ◽  
Fatemeh Mottaghitalab ◽  
Mohammad Reza Saeb ◽  
Sabu Thomas
Keyword(s):  
Photothermal Therapy ◽  
Tumor Imaging
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