scholarly journals Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures

Theranostics ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. 1792-1809 ◽  
Author(s):  
Sunil M. Kurian ◽  
Marta Novais ◽  
Thomas Whisenant ◽  
Terri Gelbart ◽  
Joel N. Buxbaum ◽  
...  
Keyword(s):  
Gene Expression ◽  
Blood Cell ◽  
Peripheral Blood ◽  
Peripheral Blood Cell ◽  
Transthyretin Amyloidosis ◽  
Male And Female ◽  
Cell Gene Expression ◽  
Female Specific ◽  
Cell Gene

scholarly journals P-141 The contribution of white blood cell gene expression in the prediction of gastrointestinal cancer

2020 ◽  
Vol 31 ◽  
pp. S135-S136
Author(s):  
P. Apostolou ◽  
P. Parsonidis ◽  
A. Iliopoulos ◽  
I. Papasotiriou
Keyword(s):  
Gene Expression ◽  
Blood Cell ◽  
White Blood Cell ◽  
Gastrointestinal Cancer ◽  
Cell Gene Expression ◽  
Cell Gene

Blood cell gene expression profiling in rheumatoid arthritis

2004 ◽  
Vol 93 (2-3) ◽  
pp. 217-226 ◽  
Author(s):  
Lone Frier Bovin ◽  
Klaus Rieneck ◽  
Christopher Workman ◽  
Henrik Nielsen ◽  
Søren Freiesleben Sørensen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Gene Expression ◽  
Blood Cell ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Cell Gene Expression ◽  
Cell Gene

scholarly journals Analysis of cell-specific peripheral blood biomarkers in severe allergic asthma identifies innate immune dysfunction

2022 ◽  
Author(s):  
Ben Nicholas ◽  
Jane Guo ◽  
Hyun-Hee Lee ◽  
Alistair Bailey ◽  
Rene de Waal Malefyt ◽  
...  
Keyword(s):  
Gene Expression ◽  
Blood Cell ◽  
Nk Cells ◽  
Allergic Asthma ◽  
Peripheral Blood ◽  
Immune Cell ◽  
Peripheral Blood Cell ◽  
Response To Treatment ◽  
Specific Gene ◽  
Severe Allergic Asthma

Asthma is a disease of complex origin and multiple pathologies. There are currently very few biomarkers of proven utility in its diagnosis, management or response to treatment. Recent studies have identified multiple asthma phenotypes following biofluid analysis; however, such findings may be driven by the well-characterised alterations in immune cell populations in asthma. We present a study designed to identify cell type-specific gene signatures of severe allergic asthma in peripheral blood samples. Using transcriptomic profiling of four magnetically purified peripheral blood cell types, we identify significant gene expression changes in monocytes and NK cells but not T lymphocytes in severe asthmatics. Pathway analysis indicates dysfunction of immune cell regulation and bacterial suppression in the NK cells. These gene expression changes may be useful on their own as prognostic peripheral blood cell markers of severe asthma, but also may indicate novel cell pathways for therapeutic intervention.

scholarly journals Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study

2019 ◽  
Vol 28 (8) ◽  
pp. 1381-1391
Author(s):  
Jaakko Laaksonen ◽  
Ilkka Seppälä ◽  
Emma Raitoharju ◽  
Nina Mononen ◽  
Leo-Pekka Lyytikäinen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Mitochondrial Dna ◽  
Blood Cell ◽  
Population Based ◽  
Genome Wide ◽  
Dna Variants ◽  
Cell Gene Expression ◽  
Mitochondrial Dna Variants ◽  
Cell Gene

Blood Cell Gene Expression Profiling in Subjects With Aggressive Periodontitis and Chronic Arthritis

2008 ◽  
Vol 79 (3) ◽  
pp. 477-485 ◽  
Author(s):  
Lars K. Sørensen ◽  
Anne Havemose-Poulsen ◽  
Søren U. Sønder ◽  
Klaus Bendtzen ◽  
Palle Holmstrup
Keyword(s):  
Gene Expression ◽  
Blood Cell ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Aggressive Periodontitis ◽  
Chronic Arthritis ◽  
Cell Gene Expression ◽  
Cell Gene
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