scholarly journals Review on Optical Imaging Techniques for Multispectral Analysis of Nanomaterials

2022 ◽  
Vol 6 (1) ◽  
pp. 50-61
Author(s):  
Haeni Lee ◽  
Jaeheung Kim ◽  
Hyung-Hoi Kim ◽  
Chang-Seok Kim ◽  
Jeesu Kim
Keyword(s):  
Optical Imaging ◽  
Imaging Techniques ◽  
Multispectral Analysis

scholarly journals Optical Imaging of Beta-Amyloid Plaques in Alzheimer’s Disease

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 255
Author(s):  
Ziyi Luo ◽  
Hao Xu ◽  
Liwei Liu ◽  
Tymish Y. Ohulchanskyy ◽  
Junle Qu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optical Imaging ◽  
Imaging Techniques ◽  
High Sensitivity ◽  
Pathological Feature ◽  
Promising Tool ◽  
Abnormal Accumulation ◽  
Accumulation Mechanism ◽  
The Brain

Alzheimer’s disease (AD) is a multifactorial, irreversible, and incurable neurodegenerative disease. The main pathological feature of AD is the deposition of misfolded β-amyloid protein (Aβ) plaques in the brain. The abnormal accumulation of Aβ plaques leads to the loss of some neuron functions, further causing the neuron entanglement and the corresponding functional damage, which has a great impact on memory and cognitive functions. Hence, studying the accumulation mechanism of Aβ in the brain and its effect on other tissues is of great significance for the early diagnosis of AD. The current clinical studies of Aβ accumulation mainly rely on medical imaging techniques, which have some deficiencies in sensitivity and specificity. Optical imaging has recently become a research hotspot in the medical field and clinical applications, manifesting noninvasiveness, high sensitivity, absence of ionizing radiation, high contrast, and spatial resolution. Moreover, it is now emerging as a promising tool for the diagnosis and study of Aβ buildup. This review focuses on the application of the optical imaging technique for the determination of Aβ plaques in AD research. In addition, recent advances and key operational applications are discussed.

scholarly journals Design and Synthesis of Luminescent Lanthanide-Based Bimodal Nanoprobes for Dual Magnetic Resonance (MR) and Optical Imaging

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 354
Author(s):  
Walid Mnasri ◽  
Mahsa Parvizian ◽  
Souad Ammar-Merah
Keyword(s):  
Magnetic Resonance ◽  
Optical Imaging ◽  
Imaging Technique ◽  
Imaging Techniques ◽  
Design And Synthesis ◽  
Bimodal Imaging ◽  
Successive Image ◽  
Complete Set ◽  
Magnetic Resonance Imaging Mri ◽  
Physical And Chemical

Current biomedical imaging techniques are crucial for the diagnosis of various diseases. Each imaging technique uses specific probes that, although each one has its own merits, do not encompass all the functionalities required for comprehensive imaging (sensitivity, non-invasiveness, etc.). Bimodal imaging methods are therefore rapidly becoming an important topic in advanced healthcare. This bimodality can be achieved by successive image acquisitions involving different and independent probes, one for each mode, with the risk of artifacts. It can be also achieved simultaneously by using a single probe combining a complete set of physical and chemical characteristics, in order to record complementary views of the same biological object at the same time. In this scenario, and focusing on bimodal magnetic resonance imaging (MRI) and optical imaging (OI), probes can be engineered by the attachment, more or less covalently, of a contrast agent (CA) to an organic or inorganic dye, or by designing single objects containing both the optical emitter and MRI-active dipole. If in the first type of system, there is frequent concern that at some point the dye may dissociate from the magnetic dipole, it may not in the second type. This review aims to present a summary of current activity relating to this kind of dual probes, with a special emphasis on lanthanide-based luminescent nano-objects.

scholarly journals The use of optical imaging techniques in the gastrointestinal tract

2015 ◽  
Vol 7 (3) ◽  
pp. 207-215 ◽  
Author(s):  
Sabina Beg ◽  
Ana Wilson ◽  
Krish Ragunath
Keyword(s):  
Gastrointestinal Tract ◽  
Optical Imaging ◽  
Imaging Techniques

Optical imaging techniques for dental biomaterials interfaces

2008 ◽  
Author(s):  
P Pilecki ◽  
S Sauro ◽  
F Festy ◽  
R Cook ◽  
T Watson
Keyword(s):  
Optical Imaging ◽  
Imaging Techniques

scholarly journals Surface chemistry and morphology in single particle optical imaging

Nanophotonics ◽  
2017 ◽  
Vol 6 (4) ◽  
pp. 713-730 ◽  
Author(s):  
Fulya Ekiz-Kanik ◽  
Derin Deniz Sevenler ◽  
Neşe Lortlar Ünlü ◽  
Marcella Chiari ◽  
M. Selim Ünlü
Keyword(s):  
Optical Imaging ◽  
Imaging Techniques ◽  
High Specificity ◽  
Physical Structure ◽  
Dark Field ◽  
Imaging Systems ◽  
Label Free ◽  
Inhomogeneous Surface ◽  
Improve Measurement ◽  
Molecular Specificity

AbstractBiological nanoparticles such as viruses and exosomes are important biomarkers for a range of medical conditions, from infectious diseases to cancer. Biological sensors that detect whole viruses and exosomes with high specificity, yet without additional labeling, are promising because they reduce the complexity of sample preparation and may improve measurement quality by retaining information about nanoscale physical structure of the bio-nanoparticle (BNP). Towards this end, a variety of BNP biosensor technologies have been developed, several of which are capable of enumerating the precise number of detected viruses or exosomes and analyzing physical properties of each individual particle. Optical imaging techniques are promising candidates among broad range of label-free nanoparticle detectors. These imaging BNP sensors detect the binding of single nanoparticles on a flat surface functionalized with a specific capture molecule or an array of multiplexed capture probes. The functionalization step confers all molecular specificity for the sensor’s target but can introduce an unforeseen problem; a rough and inhomogeneous surface coating can be a source of noise, as these sensors detect small local changes in optical refractive index. In this paper, we review several optical technologies for label-free BNP detectors with a focus on imaging systems. We compare the surface-imaging methods including dark-field, surface plasmon resonance imaging and interference reflectance imaging. We discuss the importance of ensuring consistently uniform and smooth surface coatings of capture molecules for these types of biosensors and finally summarize several methods that have been developed towards addressing this challenge.

Optical Imaging Techniques in Skin Imaging Diagnosis

2011 ◽  
Vol 38 (2) ◽  
pp. 0201001
Author(s):  
席鹏 Xi Peng ◽  
刘宇嘉 Liu Yujia ◽  
姚志荣 Yao Zhirong ◽  
任秋实 Ren Qiushi
Keyword(s):  
Optical Imaging ◽  
Imaging Techniques ◽  
Imaging Diagnosis ◽  
Skin Imaging

Multimodal optical imaging

2003 ◽  
Vol 285 (2) ◽  
pp. L269-L280 ◽  
Author(s):  
Cindy Lawler ◽  
William A. Suk ◽  
Bruce R. Pitt ◽  
Claudette M. St. Croix ◽  
Simon C. Watkins
Keyword(s):  
Optical Imaging ◽  
Imaging Techniques ◽  
Basic Research ◽  
Optical Methods ◽  
Resonance Imaging ◽  
X Ray ◽  
Positron Emission ◽  
Technological Advances ◽  
Visual Imaging ◽  
Made In

The recent resurgence of interest in the use of intravital microscopy in lung research is a manifestation of extraordinary progress in visual imaging and optical microscopy. This review evaluates the tools and instrumentation available for a number of imaging modalities, with particular attention to recent technological advances, and addresses recent progress in use of optical imaging techniques in basic pulmonary research. 1 Limitations of existing methods and anticipated future developments are also identified. Although there have also been major advances made in the use of magnetic resonance imaging, positron emission tomography, and X-ray and computed tomography to image intact lungs and while these technologies have been instrumental in advancing the diagnosis and treatment of patients, the purpose of this review is to outline developing optical methods that can be evaluated for use in basic research in pulmonary biology.

Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques

2017 ◽  
Vol 32 (7) ◽  
pp. 1535-1544 ◽  
Author(s):  
P. Sharma ◽  
K. Sahu ◽  
P. K. Kushwaha ◽  
S. Kumar ◽  
M. K. Swami ◽  
...  
Keyword(s):  
Gamma Irradiation ◽  
Optical Imaging ◽  
Imaging Techniques ◽  
Whole Body ◽  
Noninvasive Assessment
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