scholarly journals Multifunctional PEGylated Albumin/IR780/Iron Oxide Nanocomplexes for Cancer Photothermal Therapy and MR Imaging

2018 ◽  
Vol 2 (2) ◽  
pp. 106-116 ◽  
Author(s):  
Ssu-Yu Lin ◽  
Rih-Yang Huang ◽  
Wei-Chen Liao ◽  
Chun-Chiao Chuang ◽  
Chien-Wen Chang
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Photothermal Therapy

scholarly journals Bifunctional Gold Nanoshells with a Superparamagnetic Iron Oxide−Silica Core Suitable for Both MR Imaging and Photothermal Therapy

2007 ◽  
Vol 111 (17) ◽  
pp. 6245-6251 ◽  
Author(s):  
Xiaojun Ji ◽  
Ruping Shao ◽  
Andrew M. Elliott ◽  
R. Jason Stafford ◽  
Emilio Esparza-Coss ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Photothermal Therapy ◽  
Superparamagnetic Iron Oxide ◽  
Gold Nanoshells ◽  
Silica Core

Iron-Oxide Nanocluster Labeling of Clostridium novyi-NT Spores for MR Imaging–Monitored Locoregional Delivery to Liver Tumors in Rat and Rabbit Models

2019 ◽  
Vol 30 (7) ◽  
pp. 1106-1115.e1
Author(s):  
Jingran Ji ◽  
Woo Ram Park ◽  
Soojeong Cho ◽  
Yihe Yang ◽  
Weiguo Li ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Liver Tumors ◽  
Clostridium Novyi

scholarly journals Macrophage-Laden Gold Nanoflowers Embedded with Ultrasmall Iron Oxide Nanoparticles for Enhanced Dual-Mode CT/MR Imaging of Tumors

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 995
Author(s):  
Yucheng Peng ◽  
Xiaomeng Wang ◽  
Yue Wang ◽  
Yue Gao ◽  
Rui Guo ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Iron Oxide Nanoparticles ◽  
Colloidal Stability ◽  
Pamam Dendrimer ◽  
Great Promise ◽  
Oxide Nanoparticles ◽  
Dual Mode ◽  
Gold Nanoflowers ◽  
Average Size

The design of multimodal imaging nanoplatforms with improved tumor accumulation represents a major trend in the current development of precision nanomedicine. To this end, we report herein the preparation of macrophage (MA)-laden gold nanoflowers (NFs) embedded with ultrasmall iron oxide nanoparticles (USIO NPs) for enhanced dual-mode computed tomography (CT) and magnetic resonance (MR) imaging of tumors. In this work, generation 5 poly(amidoamine) (G5 PAMAM) dendrimer-stabilized gold (Au) NPs were conjugated with sodium citrate-stabilized USIO NPs to form hybrid seed particles for the subsequent growth of Au nanoflowers (NFs). Afterwards, the remaining terminal amines of dendrimers were acetylated to form the dendrimer-stabilized Fe3O4/Au NFs (for short, Fe3O4/Au DSNFs). The acquired Fe3O4/Au DSNFs possess an average size around 90 nm, display a high r1 relaxivity (1.22 mM−1 s−1), and exhibit good colloidal stability and cytocompatibility. The created hybrid DSNFs can be loaded within MAs without producing any toxicity to the cells. Through the mediation of MAs with a tumor homing and immune evasion property, the Fe3O4/Au DSNFs can be delivered to tumors more efficiently than those without MAs after intravenous injection, thus significantly improving the MR/CT imaging performance of tumors. The developed MA-mediated delivery system may hold great promise for enhanced tumor delivery of other contrast agents or nanomedicines for precision cancer nanomedicine applications.

MR imaging with i.v. superparamagnetic iron oxide: efficacy in the detection of focal hepatic lesions.

1993 ◽  
Vol 161 (6) ◽  
pp. 1191-1198 ◽  
Author(s):  
T C Winter ◽  
P C Freeny ◽  
H V Nghiem ◽  
L A Mack ◽  
R M Patten ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Superparamagnetic Iron Oxide ◽  
Focal Hepatic Lesions ◽  
Hepatic Lesions

Superparamagnetic Iron Oxide Enhanced MR Imaging: Influence of Hepatic Dysfunction in Cirrhotic Patients

2000 ◽  
Vol 43 (3) ◽  
pp. 319
Author(s):  
Hyo Sung Kwak ◽  
Jeong Min Lee ◽  
Seong Hee Ym ◽  
Chong Soo Kim ◽  
Hyun Young Han
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Hepatic Dysfunction ◽  
Superparamagnetic Iron Oxide ◽  
Cirrhotic Patients

MR imaging of murine arthritis using ultrasmall superparamagnetic iron oxide particles☆

2001 ◽  
Vol 19 (9) ◽  
pp. 1209-1216 ◽  
Author(s):  
Bernard J Dardzinski ◽  
Vincent J Schmithorst ◽  
Scott K Holland ◽  
Gregory P Boivin ◽  
Tomoyuki Imagawa ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Superparamagnetic Iron Oxide ◽  
Iron Oxide Particles ◽  
Ultrasmall Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles

LAPONITE®-stabilized iron oxide nanoparticles for in vivo MR imaging of tumors

2016 ◽  
Vol 4 (3) ◽  
pp. 474-482 ◽  
Author(s):  
Ling Ding ◽  
Yong Hu ◽  
Yu Luo ◽  
Jianzhi Zhu ◽  
Yilun Wu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Iron Oxide Nanoparticles ◽  
Colloidal Stability ◽  
Coprecipitation Method ◽  
Oxide Nanoparticles

LAPONITE®-stabilized iron oxide nanoparticles with great colloidal stability and high T2 relaxivity are synthesized by a facile controlled coprecipitation method, and can significantly enhance the contrast of tumors in vivo, indicating their tremendous potential in MR imaging applications.

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