scholarly journals Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis

2014 ◽  
Vol 5 (7) ◽  
pp. 510-517 ◽  
Author(s):  
Dun-Fa Peng ◽  
Tian-Ling Hu ◽  
Mohammed Soutto ◽  
Abbes Belkhiri ◽  
Wael El-Rifai
Author(s):  
Anna A. Karan ◽  
Yulia S. Spivak ◽  
Konstantin A. Gerasimov ◽  
Elena M. Suleymanova ◽  
Maria N. Volobueva ◽  
...  

2015 ◽  
Vol 403 (1-2) ◽  
pp. 95-106 ◽  
Author(s):  
Rajeshwari H. Patil ◽  
R. L. Babu ◽  
M. Naveen Kumar ◽  
K. M. Kiran Kumar ◽  
Shubha M. Hegde ◽  
...  

Author(s):  
Raffaella M. Gadaleta ◽  
Bas Oldenburg ◽  
Ellen C.L. Willemsen ◽  
Maureen Spit ◽  
Stefania Murzilli ◽  
...  

2003 ◽  
Vol 70 ◽  
pp. 125-133 ◽  
Author(s):  
Tim E. Cawston ◽  
Jenny M. Milner ◽  
Jon B. Catterall ◽  
Andrew D. Rowan

We have investigated proteinases that degrade cartilage collagen. We show that pro-inflammatory cytokines act synergistically with oncastatin M to promote cartilage collagen resorption by the up-regulation and activation of matrix metalloproteinases (MMPs). The precise mechanisms are not known, but involve the up-regulation of c-fos, which binds to MMP promoters at a proximal activator protein-1 (AP-1) site. This markedly up-regulates transcription and leads to higher levels of active MMP proteins.


Sign in / Sign up

Export Citation Format

Share Document