scholarly journals Histologic Lymph Nodes Regression after Preoperative Chemotherapy as Prognostic Factor in Non-metastatic Advanced Gastric Adenocarcinoma

2021 ◽  
Vol 12 (6) ◽  
pp. 1669-1677
Author(s):  
Augustinas Bausys ◽  
Veslava Senina ◽  
Martynas Luksta ◽  
Giedre Anglickiene ◽  
Greta Molnikaite ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Lymph Nodes ◽  
Gastric Adenocarcinoma ◽  
Preoperative Chemotherapy ◽  
Advanced Gastric Adenocarcinoma

scholarly journals Metastasis, Risk Factors and Prognostic Significance of Splenic Hilar Lymph Nodes in Gastric Adenocarcinoma

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99650 ◽  
Author(s):  
Xiao-Long Chen ◽  
Kun Yang ◽  
Wei-Han Zhang ◽  
Xin-Zu Chen ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lymph Nodes ◽  
Gastric Adenocarcinoma ◽  
Prognostic Significance

scholarly journals A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis

2016 ◽  
Vol 16 (2) ◽  
pp. 115 ◽  
Author(s):  
Ch'angbum Rim ◽  
Jung-Ae Lee ◽  
Soojung Gong ◽  
Dong Wook Kang ◽  
Heebum Yang ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Complete Remission ◽  
Gastric Adenocarcinoma ◽  
Advanced Gastric Adenocarcinoma

scholarly journals The presence of metastases in regional lymph nodes is associated with tumor size and depth of invasion in sporadic gastric adenocarcinoma

2014 ◽  
Vol 27 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Eduardo CAMBRUZZI ◽  
Andreza Mariane de AZEREDO ◽  
Ardala KRONHART ◽  
Katia Martins FOLTZ ◽  
Cláudio Galeano ZETTLER ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Gastric Adenocarcinoma ◽  
Tumor Size ◽  
Perineural Invasion ◽  
Histological Grade ◽  
Lymph Node Status ◽  
Depth Of Invasion ◽  
Tumor Spread ◽  
Signet Ring

Background: Gastric adenocarcinoma is more often found in men over 50 years in the form of an antral lesion. The tumor has heterogeneous histopathologic features and a poor prognosis (median survival of 15% in five years). Aim: To estimate the relationship between the presence of nodal metastasis and other prognostic factors in sporadic gastric adenocarcinoma. Method: Were evaluated 164 consecutive cases of gastric adenocarcinoma previously undergone gastrectomy (partial or total), without clinical evidence of distant metastasis, and determined the following variables: topography of the lesion, tumor size, Borrmann macroscopic configuration, histological grade, early or advanced lesions, Lauren histological subtype, presence of signet ring cell, degree of invasion, perigastric lymph node status, angiolymphatic/perineural invasion, and staging. Results: Were found 21 early lesions (12.8%) and 143 advanced lesions (87.2%), with a predominance of lesions classified as T3 (n=99/60, 4%) and N1 (n=62/37, 8%). The nodal status was associated with depth of invasion (p<0.001) and tumor size (p<0.001). The staging was related to age (p=0.048), histological grade (p=0.003), and presence of signet ring cells (p = 0.007), angiolymphatic invasion (p = 0.001), and perineural invasion (p=0.003). Conclusion: In gastric cancer, lymph node involvement, tumor size and depth of invasion are histopathological data associated with the pattern of growth/tumor spread, suggesting that a wide dissection of perigastric lymph nodes is a fundamental step in the surgical treatment of these patients.

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