scholarly journals Deep Learning Model as a New Trend in Computer-aided Diagnosis of Tumor Pathology for Lung Cancer

2020 ◽  
Vol 11 (12) ◽  
pp. 3615-3622 ◽  
Author(s):  
Lei Cong ◽  
Wanbing Feng ◽  
Zhigang Yao ◽  
Xiaoming Zhou ◽  
Wei Xiao
Keyword(s):  
Lung Cancer ◽  
Deep Learning ◽  
Learning Model ◽  
Computer Aided Diagnosis ◽  
Tumor Pathology ◽  
Computer Aided ◽  
Deep Learning Model ◽  
Aided Diagnosis

scholarly journals Hybrid CNN assisted Computer Aided Diagnosis System for Glaucoma Detection and Classification: GlaucoNet+

2019 ◽  
Vol 9 (1) ◽  
pp. 3060-3072
Keyword(s):  
Deep Learning ◽  
Learning Model ◽  
Computer Aided Diagnosis ◽  
High Dimensional ◽  
Support Vector ◽  
Linear Discriminant ◽  
Glaucoma Detection ◽  
Computer Aided ◽  
Deep Learning Model ◽  
Aided Diagnosis

The exponential rise in technologies has revitalized academia-industries to achieve more efficient computer aided diagnosis systems. It becomes inevitable especially for Glaucoma detection which has been increasing with vast pace globally. Most of the existing approaches employs morphological features like optical disk and optical cup information, optical cup to disk ratio etc; however enabling optimal detection of such traits has always been challenge for researchers. On the other hand, in the last few years deep learning methods have gained widespread attention due to its ability to exploit fine grained features of images to make optimal classification decision. However, reliance of such methods predominantly depends on the presence of deep features demanding suitable feature extraction method. To achieve it major existing approaches extracts full-image features that with high dimensional kernel generates gigantically huge features, making classification computationally overburdened. Therefore, retaining optimal balance between deep features and computational overhead is of utmost significance for glaucoma detection and classification. With this motive, in this paper a novel hybrid deep learning model has been developed for Glaucoma detection and classification. The proposed Hybrid CNN model embodies Stacked Auto-Encoder (SAE) with transferable learning model AlexNet that extracts high dimensional features to make further two-class classification. To achieve computational efficiency, In addition to the classical ReLu and dropout (50%), we used Principle Component Analysis (PCA) and Linear Discriminant Analysis (LDA) algorithms. We applied 10-fold cross validation assisted Support Vector Machine classifier to perform two-class classification; Glaucomatous and Normal fundus images. Simulation results affirmed that the proposed Hybrid deep learning model with LDA feature selection and SVM-Poly classification achieves the maximum accuracy of 98.8%, precision 97.5%, recall 97.5% and F-Measure of 97.8%.

scholarly journals Quantifying the uncertainty of deep learning-based computer-aided diagnosis for patient safety

2019 ◽  
Vol 5 (1) ◽  
pp. 223-226
Author(s):  
Max-Heinrich Laves ◽  
Sontje Ihler ◽  
Tobias Ortmaier ◽  
Lüder A. Kahrs
Keyword(s):  
Monte Carlo ◽  
Patient Safety ◽  
Deep Learning ◽  
Epistemic Uncertainty ◽  
Computer Aided Diagnosis ◽  
Uncertainty Estimation ◽  
Test Time ◽  
Prediction Uncertainty ◽  
Computer Aided ◽  
Aided Diagnosis

AbstractIn this work, we discuss epistemic uncertainty estimation obtained by Bayesian inference in diagnostic classifiers and show that the prediction uncertainty highly correlates with goodness of prediction. We train the ResNet-18 image classifier on a dataset of 84,484 optical coherence tomography scans showing four different retinal conditions. Dropout is added before every building block of ResNet, creating an approximation to a Bayesian classifier. Monte Carlo sampling is applied with dropout at test time for uncertainty estimation. In Monte Carlo experiments, multiple forward passes are performed to get a distribution of the class labels. The variance and the entropy of the distribution is used as metrics for uncertainty. Our results show strong correlation with ρ = 0.99 between prediction uncertainty and prediction error. Mean uncertainty of incorrectly diagnosed cases was significantly higher than mean uncertainty of correctly diagnosed cases. Modeling of the prediction uncertainty in computer-aided diagnosis with deep learning yields more reliable results and is therefore expected to increase patient safety. This will help to transfer such systems into clinical routine and to increase the acceptance of machine learning in diagnosis from the standpoint of physicians and patients.

scholarly journals The Role and Impact of Deep Learning Methods in Computer-Aided Diagnosis Using Gastrointestinal Endoscopy

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 694
Author(s):  
Xuejiao Pang ◽  
Zijian Zhao ◽  
Ying Weng
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Clinical Practice ◽  
Gastrointestinal Endoscopy ◽  
Computer Aided Diagnosis ◽  
Learning Methods ◽  
Learning Abilities ◽  
Cad System ◽  
Computer Aided ◽  
Aided Diagnosis

At present, the application of artificial intelligence (AI) based on deep learning in the medical field has become more extensive and suitable for clinical practice compared with traditional machine learning. The application of traditional machine learning approaches to clinical practice is very challenging because medical data are usually uncharacteristic. However, deep learning methods with self-learning abilities can effectively make use of excellent computing abilities to learn intricate and abstract features. Thus, they are promising for the classification and detection of lesions through gastrointestinal endoscopy using a computer-aided diagnosis (CAD) system based on deep learning. This study aimed to address the research development of a CAD system based on deep learning in order to assist doctors in classifying and detecting lesions in the stomach, intestines, and esophagus. It also summarized the limitations of the current methods and finally presented a prospect for future research.

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