scholarly journals Preoperative evaluation of residual tumor in patients with endometrial carcinoma by using 18F-FDG PET/CT

2020 ◽  
Vol 11 (8) ◽  
pp. 2283-2288 ◽  
Author(s):  
Chunhua Wu ◽  
Ruohua Chen ◽  
Xiang Zhou ◽  
Qian Xia ◽  
Jianjun Liu
2019 ◽  
Vol 58 (01) ◽  
pp. 28-38 ◽  
Author(s):  
Milena Cerny ◽  
Vincent Dunet ◽  
Caterina Rebecchini ◽  
Dieter Hahnloser ◽  
John Prior ◽  
...  

Abstract Aim To prospectively evaluate histological significance and predictive value of changes in apparent diffusion coefficient (ADC) and 18F-FDG PET/CT parameters in locally advanced rectal cancer (LARC) after neoadjuvant radiochemotherapy (RCT). Methods Twenty-one patients with untreated LARC underwent pre-RCT and post-RCT 18F-FDG PET/CT and diffusion-weighted magnetic resonance imaging (DW-MRI), followed by surgery. For both datasets, two readers measured the tumor SUVmax, SUVmean, MTV, TLG, ADCmin, ADCmean, and respective differences (∆SUVmax, ∆SUVmean, ∆MTV, ∆TLG, ∆ADCmin, ∆ADCmean) for the whole tumor. Tumor regression grade according to Mandard (TRGm), percentage of residual tumor cells and fibrosis were estimated by two pathologists in consensus. Relationship between parameters was assessed on stepwise multivariate regression analysis and ROC curve analysis to evaluate their performance and predict the treatment response. Results Eighteen LARCs were analyzed. SUVmax and SUVmean decreased from 21.3 ± 8.9 to 9.3 ± 5.5 g/mL, (p = 0.0002) and 12.3 ± 5.1 to 5.4 ± 3.1 g/mL, (p = 0.0002), respectively, after RCT, whereas ADCmin and ADCmean increased from 396 ± 269 to 573 ± 313×10–6 mm2/s (p = 0.014) and 1159 ± 212 to 1355 ± 194×10–6 mm2/s (p = 0.0008), respectively. TRGm and percentage of residual tumor cells independently correlated with post-RCT SUVmean (β = 0.73 and β = 0.76, p < 0.001) and post-RCT SUVmax (β = 0.72 and β = 0.78, p < 0.001), whereas percentage of fibrosis independently correlated with ∆ADCmean (β = 0.38, p = 0.008). Post-RCT, SUVmax and SUVmean performed well in predicting TRGm < 3 and residual tumor cells ≤ 20 %. ΔADCmean predicted fibrosis > 70 % well. Conclusion Post-RCT SUVmean, SUVmax and ∆ADCmean are complementary parameters for respectively evaluating residual tumor burden and amount of fibrosis in LARC. However, only SUV independently correlated with TRGm.


2018 ◽  
Vol 52 (6) ◽  
pp. 445-452 ◽  
Author(s):  
Soyoung Kim ◽  
Young Tae Kim ◽  
Sunghoon Kim ◽  
Sang Wun Kim ◽  
Jung-Yun Lee ◽  
...  

2012 ◽  
Vol 125 (3) ◽  
pp. 566-571 ◽  
Author(s):  
Feng-Yuan Liu ◽  
Angel Chao ◽  
Chyong-Huey Lai ◽  
Hung-Hsueh Chou ◽  
Tzu-Chen Yen

2015 ◽  
Vol 40 (12) ◽  
pp. 936-940 ◽  
Author(s):  
Miwako Takahashi ◽  
Haruki Kume ◽  
Keitaro Koyama ◽  
Tohru Nakagawa ◽  
Tetsuya Fujimura ◽  
...  

2015 ◽  
Vol 56 (8) ◽  
pp. 1191-1198 ◽  
Author(s):  
J. A. Husby ◽  
B. C. Reitan ◽  
M. Biermann ◽  
J. Trovik ◽  
L. Bjorge ◽  
...  

2020 ◽  
Vol 98 (4) ◽  
pp. 184
Author(s):  
Atilgan Tolga Akcam ◽  
Zafer Teke ◽  
Ahmet Gokhan Saritas ◽  
Abdullah Ulku ◽  
Isa Burak Guney ◽  
...  

Author(s):  
Domenico Albano ◽  
Valentina Zizioli ◽  
Franco Odicino ◽  
Raffaele Giubbini ◽  
Francesco Bertagna

2016 ◽  
Vol 140 (3) ◽  
pp. 409-414 ◽  
Author(s):  
Hyun Ju Lee ◽  
Jeong-Yeol Park ◽  
Jong Jin Lee ◽  
Mi Hyun Kim ◽  
Dae-Yeon Kim ◽  
...  

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