scholarly journals Plasmacytoid Dendritic Cells and ICOS+ Regulatory T Cells Predict Poor Prognosis in Gastric Cancer: A Pilot Study

2019 ◽  
Vol 10 (26) ◽  
pp. 6711-6715 ◽  
Author(s):  
Xiaosun Liu ◽  
Hang Yu ◽  
Chongxian Yan ◽  
Ying Mei ◽  
Caizhao Lin ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
T Cells ◽  
Dendritic Cells ◽  
Pilot Study ◽  
Regulatory T Cells ◽  
Poor Prognosis ◽  
Plasmacytoid Dendritic Cells

scholarly journals Role of plasmacytoid dendritic cells and inducible costimulator‐positive regulatory T cells in the immunosuppression microenvironment of gastric cancer

2014 ◽  
Vol 105 (2) ◽  
pp. 150-158 ◽  
Author(s):  
Xiao‐Mei Huang ◽  
Xiao‐Sun Liu ◽  
Xian‐Ke Lin ◽  
Hang Yu ◽  
Jian‐Yi Sun ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
T Cells ◽  
Dendritic Cells ◽  
Regulatory T Cells ◽  
Plasmacytoid Dendritic Cells ◽  
Inducible Costimulator

scholarly journals FOXP3 in Melanoma with Regression: Between Tumoral Expression and Regulatory T Cell Upregulation

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Mirela Cioplea ◽  
Luciana Nichita ◽  
Daniela Georgescu ◽  
Liana Sticlaru ◽  
Alexandra Cioroianu ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Regulatory T Cells ◽  
Tumor Cells ◽  
Retrospective Cohort ◽  
Poor Prognosis ◽  
Tumor Regression ◽  
Foxp3 Expression ◽  
Immune Defense ◽  
Stromal Microenvironment

Cutaneous melanoma is a significant immunogenic tumoral model, the most frequently described immune phenomenon being tumor regression, as a result of the interaction of tumoral antigens and stromal microenvironment. We present a retrospective cohort study including 52 cases of melanoma with regression. There were evaluated correlations of the most important prognostic factors (Breslow depth and mitotic index) with FOXP3 expression in tumor cells and with the presence of regulatory T cells and dendritic cells in the tumoral stroma. FOXP3 expression in tumor cells seems an independent factor of poor prognosis in melanoma, while regression areas are characterized by a high number of dendritic cells and a low number of regulatory T cells. FOXP3 is probably a useful therapeutical target in melanoma, since inhibition of FOXP3-positive tumor clones and of regulatory T cells could eliminate the ability of tumor cells to escape the immune defense of the host.

scholarly journals Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+Regulatory T Cells in Human Thymus

2010 ◽  
Vol 184 (6) ◽  
pp. 2999-3007 ◽  
Author(s):  
Shino Hanabuchi ◽  
Tomoki Ito ◽  
Woon-Ryon Park ◽  
Norihiko Watanabe ◽  
Joanne L. Shaw ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Regulatory T Cells ◽  
Plasmacytoid Dendritic Cells ◽  
Thymic Stromal Lymphopoietin ◽  
Human Thymus

scholarly journals Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner

2016 ◽  
Vol 12 (12) ◽  
pp. e1006115 ◽  
Author(s):  
Eliseu Frank de Araújo ◽  
Daniella Helena Medeiros ◽  
Nayane Alves de Lima Galdino ◽  
Antônio Condino-Neto ◽  
Vera Lúcia Garcia Calich ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Regulatory T Cells ◽  
Paracoccidioides Brasiliensis ◽  
Plasmacytoid Dendritic Cells ◽  
Dependent Manner
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