scholarly journals Impact of Polymorphisms in Casein Kinase 1 Epsilon and Environmental Factors in Oral Cancer Susceptibility

2019 ◽  
Vol 10 (21) ◽  
pp. 5065-5069
Author(s):  
Shu-Hui Lin ◽  
Mu-Kuan Chen ◽  
Julia Hueimei Chang ◽  
Bharath Kumar Velmurugan ◽  
Madhavi Annamanedi ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Environmental Factors ◽  
Cancer Susceptibility ◽  
Casein Kinase ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon

scholarly journals Casein Kinase 1 Epsilon Expression Predicts Poorer Prognosis in Low T-Stage Oral Cancer Patients

2014 ◽  
Vol 15 (2) ◽  
pp. 2876-2891 ◽  
Author(s):  
Shu-Hui Lin ◽  
Yueh-Min Lin ◽  
Chung-Min Yeh ◽  
Chih-Jung Chen ◽  
Mei-Wen Chen ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Casein Kinase ◽  
Casein Kinase 1 ◽  
T Stage ◽  
Oral Cancer Patients ◽  
Casein Kinase 1 Epsilon

345 UPREGULATION OF CASEIN KINASE 1 EPSILON AFTER SPINAL NERVE INJURY CONTRIBUTES TO NEUROPATHIC PAIN

2010 ◽  
Vol 4 (S1) ◽  
pp. 99-99
Author(s):  
T. Tanabe ◽  
E. Sakurai ◽  
T. Kurihara ◽  
K. Kouchi ◽  
H. Saegusa ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Nerve Injury ◽  
Spinal Nerve ◽  
Casein Kinase ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon

A Population-based Association Study of Casein Kinase 1 Epsilon Loci with Heroin Dependence in Han Chinese

2013 ◽  
Vol 53 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Yunpeng Wang ◽  
Yongsheng Zhu ◽  
Wei Wang ◽  
Feng Wu ◽  
Haimin Cui ◽  
...  
Keyword(s):  
Association Study ◽  
Population Based ◽  
Casein Kinase ◽  
Han Chinese ◽  
Heroin Dependence ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon

scholarly journals Altered Affective Behaviors in Casein Kinase 1 Epsilon Mutant Mice

2020 ◽  
Author(s):  
Lili Zhou ◽  
Karrie Fitzpatrick ◽  
Christopher Olker ◽  
Martha H. Vitaterna ◽  
Fred W. Turek
Keyword(s):  
Circadian Rhythms ◽  
Casein Kinase ◽  
Circadian Period ◽  
Wild Type ◽  
Casein Kinase 1 ◽  
Phenotypic Differences ◽  
Affective Behaviors ◽  
Casein Kinase 1 Epsilon ◽  
Fear And Anxiety ◽  
Mutant Lines

AbstractAffective behaviors and mental health are profoundly affected by disturbances in circadian rhythms. Casein kinase 1 epsilon (CSNK1E) is an essential component of the core circadian clock. Mice with tau or null mutation of this gene have shortened and lengthened circadian period respectively. Here we examined anxiety-like, fear, and depressive-like behaviors in both male and female mice of these two different mutants. Compared with wild-type mice, we found reductions in fear and anxiety-like behaviors in both mutant lines and in both sexes, with the tau mutants exhibiting the greatest phenotypic changes. However, the depressive-like behaviors had distinct phenotypic patterns, with markedly less depressive-like behaviors in female null mutants, but not in tau mutants of either sex. To determine whether abnormal light entrainment of tau mutants to 24 hour light-dark cycles contributes to these phenotypic differences, we also examined these behaviors in tau mutants on a 20 hour light-dark cycle close to their endogenous circadian period. The normalized entrainment restored more wild-type-like behaviors for fear and anxiety, but it induced depressive-like behavior in tau mutant females. These data show that both mutations of Csnk1e broadly affect fear and anxiety-like behaviors, while the effects on depressive-like behavior vary with genetics, photoperiod, and sex, suggesting that the mechanisms by which Csnk1e affects fear and anxiety-like behaviors may be similar, but distinct from those affecting depressive-like behavior. Our study also provides experimental evidence in support of the hypothesis of beneficial outcomes from properly entrained circadian rhythms in terms of the anxiety-like and fear behaviors.

Casein kinase 1 epsilon facilitates cartilage destruction in osteoarthritis through JNK pathway

2020 ◽  
Vol 34 (5) ◽  
pp. 6466-6478 ◽  
Author(s):  
Tianwei He ◽  
Depeng Wu ◽  
Lei He ◽  
Xuan Wang ◽  
Bu Yang ◽  
...  
Keyword(s):  
Cartilage Destruction ◽  
Casein Kinase ◽  
Jnk Pathway ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon

scholarly journals Casein kinase 1‐epsilon or 1‐delta required for Wnt‐mediated intestinal stem cell maintenance

2017 ◽  
Vol 36 (20) ◽  
pp. 3046-3061 ◽  
Author(s):  
Yael Morgenstern ◽  
Upasana Das Adhikari ◽  
Muneef Ayyash ◽  
Ela Elyada ◽  
Beáta Tóth ◽  
...  
Keyword(s):  
Stem Cell ◽  
Casein Kinase ◽  
Intestinal Stem Cell ◽  
Casein Kinase 1 ◽  
Stem Cell Maintenance ◽  
Casein Kinase 1 Epsilon ◽  
Cell Maintenance

Association Between a Casein Kinase 1 Epsilon Gene Polymorphism and Schizophrenia in a Chinese Han Population

2012 ◽  
Vol 47 (3) ◽  
pp. 470-474 ◽  
Author(s):  
Yinglin Huang ◽  
Jingying Li ◽  
Lijuan Wu ◽  
Qiu Jin ◽  
Xiaofeng Zhao ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Casein Kinase ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Casein Kinase 1 ◽  
Han Population ◽  
Casein Kinase 1 Epsilon

scholarly journals Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Robin T. Varghese ◽  
Sarah Young ◽  
Lily Pham ◽  
Yanping Liang ◽  
Kevin J. Pridham ◽  
...  
Keyword(s):  
Cell Survival ◽  
Casein Kinase ◽  
Glioblastoma Cell ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon

P4-049: Upregulation of casein kinase 1 epsilon may be involved in tau pathology in Alzheimer's disease brain

2013 ◽  
Vol 9 ◽  
pp. P720-P720
Author(s):  
Fei Liu ◽  
Caoyi Chen ◽  
Nana Jin ◽  
Jianlan Gu ◽  
Gustavo Basurto-Islas ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Casein Kinase ◽  
Tau Pathology ◽  
Casein Kinase 1 ◽  
Casein Kinase 1 Epsilon
Sign in / Sign up

Export Citation Format

Share Document