scholarly journals High WNT6 expression indicates unfavorable survival outcome for patients with colorectal liver metastasis after liver resection

2019 ◽  
Vol 10 (12) ◽  
pp. 2619-2627 ◽  
Author(s):  
Jianhong Peng ◽  
Yixin Zhao ◽  
Qiuyun Luo ◽  
Hao Chen ◽  
Wenhua Fan ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastasis ◽  
Colorectal Liver Metastasis ◽  
Survival Outcome

Two-stage laparoscopic liver resection for bilateral colorectal liver metastasis

2010 ◽  
Vol 24 (8) ◽  
pp. 2044-2047 ◽  
Author(s):  
M. A. Machado ◽  
F. F. Makdissi ◽  
R. C. Surjan ◽  
G. T. Kappaz ◽  
N. Yamaguchi
Keyword(s):  
Liver Resection ◽  
Liver Metastasis ◽  
Colorectal Liver Metastasis ◽  
Laparoscopic Liver Resection ◽  
Two Stage

Impact of parenchymal preserving surgery on survival and recurrence after liver resection for colorectal liver metastasis

2016 ◽  
Vol 88 (1-2) ◽  
pp. 66-70 ◽  
Author(s):  
Sanjay Pandanaboyana ◽  
Richard Bell ◽  
Alan White ◽  
Samir Pathak ◽  
Ernest Hidalgo ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastasis ◽  
Colorectal Liver Metastasis

Impact of Margin Status and Neoadjuvant Chemotherapy on Survival, Recurrence After Liver Resection for Colorectal Liver Metastasis

2014 ◽  
Vol 22 (1) ◽  
pp. 173-179 ◽  
Author(s):  
Sanjay Pandanaboyana ◽  
Alan White ◽  
Samir Pathak ◽  
Ernest L. Hidalgo ◽  
Giles Toogood ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastasis ◽  
Neoadjuvant Chemotherapy ◽  
Colorectal Liver Metastasis ◽  
Margin Status

scholarly journals The Impact of Sarcopenia on Overall and Disease-free Survival after Liver Resection for Colorectal Liver Metastasis

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S735
Author(s):  
C.F. Fernández Mancilla ◽  
R. Rumenova Smilevska ◽  
B. Madrid Baños ◽  
J. Aparicio Navarro ◽  
M. Pujante Menchon ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastasis ◽  
Colorectal Liver Metastasis ◽  
Disease Free Survival ◽  
Free Survival ◽  
The Impact ◽  
Disease Free

scholarly journals Recurrent Colorectal Liver Metastasis Patients Would Benefit to Repeat Hepatic Resection

2021 ◽  
Author(s):  
Wei Liu ◽  
Jia-Ming Liu ◽  
Kun Wang ◽  
Hong-Wei Wang ◽  
Bao-Cai Xing
Keyword(s):  
Liver Metastasis ◽  
Hepatic Resection ◽  
Colorectal Liver Metastasis ◽  
Systemic Chemotherapy ◽  
Predictive Accuracy ◽  
Cox Model ◽  
Local Treatment ◽  
Multivariable Analysis ◽  
Survival Outcome ◽  
First Recurrence

Abstract Background Local treatment remains the best option for recurrent colorectal liver metastasis. The current study aims to investigate predictive factors of survival outcomes and select candidates of local treatment for CRLM at first recurrence. Methods Data were collected retrospectively on CRLM patients who underwent hepatic resection and developed first recurrence between 2000 and 2019 at our institution. A nomogram to predict overall survival was established based on a multivariable Cox model of clinicopathologic factors. The predictive accuracy and discriminative ability of the nomogram were determined by concordance index and calibration curve. Results Among 867 patients who underwent curative hepatic resection, 549 patients developed recurrence. Three hundred patients were evaluated to be resectable and liver-limited disease. Among of them, repeat liver resection and percutaneous radiofrequency ablation were performed in 88 and 85 patients, respectively. The other 127 patients only received systemic chemotherapy. Multivariable analysis identified node-positive primary, tumor size > 3 cm, early recurrence, RAS gene mutation and no local treatment were independent risk factors for survival outcome. Integrating these five variables, the nomogram showed good concordance statistics of 0.707. Compared with patients who only received systemic chemotherapy, radical local treatment did not improve survival outcome significantly (median OS: 21 vs. 15 months, p = 0.126) in high risk group (total score above 13). Conclusion Radical local treatment is crucial to prolong the survival of recurrent CRLM patients. The proposed model facilitates personalized assessment of prognosis for patients who developed first recurrence in liver.

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