scholarly journals May Circulating microRNAs be Gastric Cancer Diagnostic Biomarkers?

2015 ◽  
Vol 6 (12) ◽  
pp. 1206-1213 ◽  
Author(s):  
Xiaoling Wu ◽  
Xiaohui Tan ◽  
Sidney W. Fu
Keyword(s):  
Gastric Cancer ◽  
Diagnostic Biomarkers ◽  
Circulating Micrornas ◽  
Cancer Diagnostic

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

2016 ◽  
Vol 23 (36) ◽  
pp. 4135-4150 ◽  
Author(s):  
Hamed Mirzaei ◽  
Sara Khataminfar ◽  
Saeid Mohammadparast ◽  
Soudabeh Sales ◽  
Mina Maftouh ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Therapeutic Targets ◽  
Current Status ◽  
Future Perspectives ◽  
Diagnostic Biomarkers ◽  
Circulating Micrornas

scholarly journals Ascites-derived circulating microRNAs as potential diagnostic biomarkers of gastric cancer-associated malignant ascites

2019 ◽  
Vol 30 ◽  
pp. v52-v53
Author(s):  
H.S. Han ◽  
H.B. Chae ◽  
J. Yun ◽  
H.J. Kim ◽  
S.-I. Go ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Malignant Ascites ◽  
Diagnostic Biomarkers ◽  
Circulating Micrornas

scholarly journals Cross-platform genomic identification and clinical validation of breast cancer diagnostic biomarkers

Aging ◽  
2021 ◽  
Author(s):  
Dongdong Liu ◽  
Beibei Li ◽  
Xiaoshun Shi ◽  
Jiexia Zhang ◽  
Allen Menglin Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Validation ◽  
Diagnostic Biomarkers ◽  
Cancer Diagnostic ◽  
Cross Platform

Cerebrospinal fluid microRNAs as diagnostic biomarkers in brain tumors

2018 ◽  
Vol 56 (6) ◽  
pp. 869-879 ◽  
Author(s):  
Alena Kopkova ◽  
Jiri Sana ◽  
Pavel Fadrus ◽  
Ondrej Slaby
Keyword(s):  
Cerebrospinal Fluid ◽  
Brain Tumors ◽  
Communication Channel ◽  
Predictive Biomarkers ◽  
Waste Products ◽  
Diagnostic Biomarkers ◽  
Circulating Micrornas ◽  
The Central Nervous System ◽  
Non Coding Rnas ◽  
Extracellular Environment

Abstract Cerebrospinal fluid (CSF) is a body fluid that has many important functions and is in direct contact with the extracellular environment of the central nervous system (CNS). CSF serves as both the communication channel allowing the distribution of various substances among the CNS cells and the storage facility for the waste products these cells release. For these reasons, CSF is a potential source of diagnostic biomarkers of many CNS diseases, including brain tumors. Recent studies have revealed that CSF also contains circulating microRNAs (miRNAs), short non-coding RNAs that have been described as biomarkers in many cancers. However, CSF miRNAs are difficult to detect, which is why researchers face major challenges, including technological difficulties in its detection and its lack of standardization. Therefore, this review aims (i) to highlight the potential of CSF miRNAs as diagnostic, prognostic and predictive biomarkers in brain tumors, and (ii) to summarize technological approaches for detection of CSF miRNAs.

Evaluation of miR-22 and miR-20a as diagnostic biomarkers for gastric cancer

2017 ◽  
Vol 6 (2) ◽  
pp. 16-16 ◽  
Author(s):  
Zahra Jafarzadeh-Samani ◽  
Sareh Sohrabi ◽  
Khadije Shirmohammadi ◽  
Hosein Effatpanah ◽  
Reza Yadegarazari ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Diagnostic Biomarkers

scholarly journals The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression

Cells ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 394 ◽  
Author(s):  
Ana Margarida Moreira ◽  
Joana Pereira ◽  
Soraia Melo ◽  
Maria Sofia Fernandes ◽  
Patrícia Carneiro ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Extracellular Matrix ◽  
Expression Patterns ◽  
Predictive Biomarkers ◽  
Gastric Epithelium ◽  
Comprehensive Overview ◽  
Diagnostic Biomarkers ◽  
Malignant Lesions ◽  
And Behavior ◽  
Disease Stages

The extracellular matrix (ECM) is a dynamic and highly organized tissue structure, providing support and maintaining normal epithelial architecture. In the last decade, increasing evidence has emerged demonstrating that alterations in ECM composition and assembly strongly affect cellular function and behavior. Even though the detailed mechanisms underlying cell-ECM crosstalk are yet to unravel, it is well established that ECM deregulation accompanies the development of many pathological conditions, such as gastric cancer. Notably, gastric cancer remains a worldwide concern, representing the third most frequent cause of cancer-associated deaths. Despite increased surveillance protocols, patients are usually diagnosed at advanced disease stages, urging the identification of novel diagnostic biomarkers and efficient therapeutic strategies. In this review, we provide a comprehensive overview regarding expression patterns of ECM components and cognate receptors described in normal gastric epithelium, pre-malignant lesions, and gastric carcinomas. Important insights are also discussed for the use of ECM-associated molecules as predictive biomarkers of the disease or as potential targets in gastric cancer.

scholarly journals Plasma long noncoding RNAs PANDAR, FOXD2-AS1, and SMARCC2 as potential novel diagnostic biomarkers for gastric cancer

2019 ◽  
Vol Volume 11 ◽  
pp. 6175-6184 ◽  
Author(s):  
Ziwei Yang ◽  
Yanfei Sun ◽  
Rongfeng Liu ◽  
Yanyan Shi ◽  
Shigang Ding
Keyword(s):  
Gastric Cancer ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Diagnostic Biomarkers

scholarly journals Non-Invasive Biomarkers for Early Detection of Breast Cancer

Cancers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2767
Author(s):  
Jiawei Li ◽  
Xin Guan ◽  
Zhimin Fan ◽  
Lai-Ming Ching ◽  
Yan Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Early Stage ◽  
False Negative ◽  
Breast Cancer Diagnosis ◽  
Diagnostic Biomarkers ◽  
Circulating Micrornas ◽  
Non Invasive ◽  
Common Cancer ◽  
Volatile Organic

Breast cancer is the most common cancer in women worldwide. Accurate early diagnosis of breast cancer is critical in the management of the disease. Although mammogram screening has been widely used for breast cancer screening, high false-positive and false-negative rates and radiation from mammography have always been a concern. Over the last 20 years, the emergence of “omics” strategies has resulted in significant advances in the search for non-invasive biomarkers for breast cancer diagnosis at an early stage. Circulating carcinoma antigens, circulating tumor cells, circulating cell-free tumor nucleic acids (DNA or RNA), circulating microRNAs, and circulating extracellular vesicles in the peripheral blood, nipple aspirate fluid, sweat, urine, and tears, as well as volatile organic compounds in the breath, have emerged as potential non-invasive diagnostic biomarkers to supplement current clinical approaches to earlier detection of breast cancer. In this review, we summarize the current progress of research in these areas.

Su1163 ENDOSCOPIC ULTRASOUND GUIDED TISSUE ACQUISITION FOR GASTRIC CANCER DIAGNOSTIC PROFILING AS AN ADJUNCT TO ENDOSCOPIC MUCOSAL BIOPSIES

2019 ◽  
Vol 89 (6) ◽  
pp. AB295
Author(s):  
Emmanuel Coronel ◽  
Hamzah Abu-Sbeih ◽  
Irina M. Cazacu ◽  
Phillip Lum ◽  
Victor Garcia Rodriguez ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Endoscopic Ultrasound ◽  
Ultrasound Guided ◽  
Cancer Diagnostic ◽  
Tissue Acquisition

scholarly journals Circulating exosomal small RNAs are promising non‐invasive diagnostic biomarkers for gastric cancer

2020 ◽  
Vol 24 (24) ◽  
pp. 14502-14513 ◽  
Author(s):  
Lichen Ge ◽  
Nan Zhang ◽  
Dandan Li ◽  
Yingmin Wu ◽  
Hongsheng Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Small Rnas ◽  
Diagnostic Biomarkers ◽  
Non Invasive
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