scholarly journals Methicillin Resistant Staphylococcus Aureus Sacroiliac Joint Septic Arthritis in an Adult Patient Treated with Daptomycin

2017 ◽  
Vol 2 (3) ◽  
pp. 143-148
Author(s):  
Ramy Rashed ◽  
Fizan Younis
Keyword(s):  
Staphylococcus Aureus ◽  
Septic Arthritis ◽  
Adult Patient ◽  
Rare Disease ◽  
Sacroiliac Joint ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
The Novel ◽  
Disease Entity ◽  
Methicillin Resistant ◽  
Iliopsoas Abscess

Abstract. Sacroiliac joint septic arthritis is a rare disease entity representing 1-2% of all cases of septic arthritis. Establishment of the diagnosis is often challenging given the non-specific presenting features and the potential cross-over with other pathologies. We report the case of a 50 year old gentleman who suffers with psoriasis and presented with sacroiliac joint septic arthritis complicated by Methicillin Resistant Staphylococcus Aureus (MRSA) bacteraemia and an iliopsoas abscess. This was successfully treated conservatively with a course of the novel antibiotic Daptomycin.

scholarly journals High Prevalence of Methicillin-Resistant Staphylococcus aureus among Patients with Septic Arthritis Caused by Staphylococcus aureus

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0127150 ◽  
Author(s):  
Wei-Ting Lin ◽  
Chung-Da Wu ◽  
Shun-Chien Cheng ◽  
Chong-Chi Chiu ◽  
Chi-Chou Tseng ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Septic Arthritis ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
High Prevalence

scholarly journals A Case of Adult Membranous Croup Caused by Methicillin-Resistant Staphylococcus Aureus Mimicking Laryngeal Diphtheria

2020 ◽  
Vol 63 (5) ◽  
pp. 233-237
Author(s):  
Chanhyeon Park ◽  
Dong Hoo Lee ◽  
Sung Yool Park ◽  
Do Hun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Rare Disease ◽  
Rare Case ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Signs ◽  
Review Of Literature ◽  
Methicillin Resistant ◽  
Diffuse Inflammation ◽  
High Degree ◽  
Trachea And Bronchi

Membranous croup is a rare disease that is characterized by diffuse inflammation of the larynx, trachea, and bronchi with adherent or semiadherent mucopurulent membranes in the subglottic trachea and larynx. All cases have occurred in children and there has been no case of adults. The clinical signs, symptoms, progress and prognosis of membranous croup are more severe than those of ordinary croup. The detached membrane in membranous croup may cause a high degree of air way obstruction and give similar characteristics of laryngeal diphtheria, thus it is important to differentiate it from diphtheria by identifying the pathogen. Herein we report with a review of literature a rare case of adult membranous croup caused by methicillin-resistant staphylococcus aureus mimicking laryngeal diphtheria.

scholarly journals Adult Native Joint Septic Arthritis: A Nine-Year Retrospective Analysis in a Portuguese University Hospital

2021 ◽  
Vol 34 (13) ◽  
Author(s):  
Ana Cipriano ◽  
Fábio Videira Santos ◽  
Rita Dias ◽  
André Carvalho ◽  
Ernestina Reis ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Septic Arthritis ◽  
Retrospective Analysis ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Empirical Treatment ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Methicillin Resistant ◽  
Wide Range ◽  
Amoxicillin Clavulanate

Introduction: Septic arthritis of a native joint represents a medical emergency. Drainage and effective antibiotic treatment are critical to avoid joint destruction and long-term impairment. The aim of this study was to evaluate epidemiological and clinical characteristics of patients with the diagnosis of septic arthritis to help establish local guidelines for empirical antibiotic treatment.Material and Methods: Retrospective analysis of adult patients admitted at Centro Hospitalar Universitário do Porto from 2009 to 2017 with suspected native joint septic arthritis. Relevant demographics, microbiology findings and respective antibiotic susceptibilities were analysed.Results: Ninety-seven patients, predominantly males (59.8%) with a median age of 61 years old were included. The most commonly reported comorbidity associated with septic arthritis was diabetes mellitus (20.6%). The knee was the most commonly affected joint (71.1%). Arthrocentesis was performed in all patients, but only 50.5% had positive microbial growth in the synovial fluid. Staphylococcus aureus was the most frequently identified microorganism, 86% of which were methicillin susceptible. Gram-negative bacteria were the causative agent in 15% of cases. A wide range of empirical antibiotic regimens were prescribed with a combination of vancomycin/carbapenem being the most common (30.9%). Analysis of antibiotic susceptibility profiles revealed that amoxicillin/clavulanate would have been appropriate as the initial regimen in 89% of cases.Discussion: The main causative pathogen was Staphylococcus aureus, with methicillin resistant Staphylococcus aureus remaining rare. The proportion of Gram-negative bacteria implies that these agents should be covered by empirical treatment, although no case of Pseudomonas infection has been identified. Therefore, antipseudomonal coverage is not necessary in empirical regimens.Conclusion: Routine coverage of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa is not warranted but must be considered when specific risk factors are found. Amoxicillin/clavulanate can provide adequate antibiotic coverage as an empirical treatment for adult native joint septic arthritis. Its use may allow a reduction in use of broader spectrum antibiotics.

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