scholarly journals Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients

2006 ◽  
pp. 92-96 ◽  
Author(s):  
Tsutomu Nakamura ◽  
Takeshi Ioroi ◽  
Toshiyuki Sakaeda ◽  
Masanori Horinouchi ◽  
Nobuhide Hayashi ◽  
...  
Keyword(s):  
Serum Concentration ◽  
Cystatin C ◽  
Japanese Patients ◽  
Serum Cystatin C ◽  
Serum Cystatin

Usefulness of serum cystatin C in Japanese patients with type 2 diabetes mellitus and nephropathy

2009 ◽  
Vol 83 (2) ◽  
pp. e58-e61 ◽  
Author(s):  
Tetsuya Kimura ◽  
Hiroki Ikeda ◽  
Jun Fujikawa ◽  
Kazuhiro Nomura ◽  
Tomohisa Aoyama ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cystatin C ◽  
Japanese Patients ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Usefulness of Serum Cystatin C Measurement for Assessing Renal Function in Cats

2012 ◽  
Vol 56 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Iwona Poświatowska-Kaszczyszyn
Keyword(s):  
Renal Failure ◽  
Serum Concentration ◽  
Renal Dysfunction ◽  
Cystatin C ◽  
High Performance ◽  
Characteristic Curve ◽  
Compartment Model ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Group I

Abstract The aim of the work was to determine the concentration of serum cystatin C and usability of its measurement in diagnostics of renal failure in cats. The reference point was the value of glomerular filtration rate (GFR), calculated on the basis of plasma clearance of iohexol (Pcio). Seventy cats were divided into two groups: group I - 24 healthy cats, group II - 46 cats affected with renal dysfunction. The measurement of serum cystatin C was done according to immunonefelometric method. In order to estimate Pcio, the following blood samples were collected: pre-sample - 0, and samples collected 120, 180, 240, and 300 min after intravenous administration of iohexol. Its concentration was determined using high performance liquid chromatography. Pcio was obtained using a one-compartment model, according to the method developed by Krutzen Back and Nilsson-Ehl. Serum concentration of cystatin C in cats with renal dysfunction was significantly statistically higher (1.3 ± 0.6 mg/L) as compared to the group of healthy animals (0.7 ± 0.2 mg/L). Statistical analysis of the data confirmed strong correlation between GFR and serum concentration of cystatin C (r = - 0.51). Data analysis on the basis of the receiver operating characteristic curve proved that cystatin C seems to be more reliable parameter than creatinine in the assessment of kidneys function in cats and the measurement of cystatin C in blood serum can be of a considerable meaning as far as early diagnosis of renal failure in cats is concerned.

509-P: Utility of Serum Cystatin C in Early Kidney Dysfunction in Prediabetics

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 509-P
Author(s):  
JULIA I.F. BRANDA ◽  
BIANCA ALMEIDA ◽  
SANDRA R.G. VIVOLO
Keyword(s):  
Cystatin C ◽  
Kidney Dysfunction ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Reference intervals for serum cystatin C and serum creatinine in an adult sub-Saharan African population

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Bertille Elodie Edinga-Melenge ◽  
Adrienne Tchapmi Yakam ◽  
Jobert Richie Nansseu ◽  
Catherine Bilong ◽  
Suzanne Belinga ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
Cystatin C ◽  
Reference Intervals ◽  
African Population ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Sub Saharan

scholarly journals Assessment of Subclinical Renal Glomerular and Tubular Dysfunction in Children with Beta Thalassemia Major

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 100
Author(s):  
Asmaa A. Mahmoud ◽  
Doaa M. Elian ◽  
Nahla MS. Abd El Hady ◽  
Heba M. Abdallah ◽  
Shimaa Abdelsattar ◽  
...  
Keyword(s):  
Cystatin C ◽  
Kidney Injury ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Good Survival ◽  
Control Group ◽  
Healthy Children ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Beta Thalassemia Major

Background: A good survival rate among patients with beta thalassemia major (beta-TM) has led to the appearance of an unrecognized renal disease. Therefore, we aimed to assess the role of serum cystatin-C as a promising marker for the detection of renal glomerular dysfunction and N-acetyl beta-D-glucosaminidase (NAG) and kidney injury molecule 1 (KIM-1) as potential markers for the detection of renal tubular injury in beta-TM children. Methods: This case-control study was implemented on 100 beta-TM children receiving regular blood transfusions and undergoing iron chelation therapy and 100 healthy children as a control group. Detailed histories of complete physical and clinical examinations were recorded. All subjected children underwent blood and urinary investigations. Results: There was a significant increase in serum cystatin-C (p < 0.001) and a significant decrease in eGFR in patients with beta-TM compared with controls (p = 0.01). There was a significant increase in urinary NAG, KIM-1, UNAG/Cr, and UKIM-1/Cr (p < 0.001) among thalassemic children, with a significant positive correlation between serum cystatin-C, NAG and KIM-1 as regards serum ferritin, creatinine, and urea among thalassemic patients. A negative correlation between serum cystatin-C and urinary markers with eGFR was noted. Conclusion: Serum cystatin-C is a good marker for detection of glomerular dysfunction. NAG and KIM-1 may have a predictive role in the detection of kidney injury in beta-TM children.

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