scholarly journals Efficacy and safety of nucleos(t)ide analogues to prevent hepatitis B virus mother-to-child transmission in pregnant women with high viremia: real life practice from China

2018 ◽  
Vol 15 (8) ◽  
pp. 796-801 ◽  
Author(s):  
Qiuju Sheng ◽  
Yang Ding ◽  
Baijun Li ◽  
Chao Han ◽  
Yanwei Li ◽  
...  
Medicine ◽  
2021 ◽  
Vol 100 (44) ◽  
pp. e27695
Author(s):  
Bo Zhu ◽  
Xiaojing Lv ◽  
Zhiying Zhao ◽  
Liwen Chen ◽  
Xiuli Chen ◽  
...  

2013 ◽  
Vol 7 (05) ◽  
pp. 391-397 ◽  
Author(s):  
Yali Hu ◽  
Xinwei Dai ◽  
Yi-Hua Zhou ◽  
Huixia Yang

Introduction: This survey was designed to investigate the knowledge awareness of obstetrics and gynaecology staff (Obs/Gyn staff) on the prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV). Methodology: Obs/Gyn staff from 21 of the 31 Chinese mainland provinces, who attended medical meetings or training classes from July to October 2011, were invited to complete a questionnaire regarding PMTCT of HBV. The questionnaire included the clinical implications of HBV serologic markers and PMTCT preventive measures for both pregnant women and infants. Results: A total of 828 questionnaires were distributed, 617 (74.5%) Obs/Gyn staff participated in the survey, and 559 (90.6%) questionnaires met the inclusion criteria. Overall, 90% of participants correctly determined the positive hepatitis B surface antigen (HBsAg) as infectious, but up to 27.5% mistakenly considered the presence of anti-HBe and/or anti-HBc with negative HBsAg as infectious. In total, 96.3% respondents knew that pregnant women should be screened for HBV infection, and 95.3% realized that infants of HBsAg-positive mothers should be injected with hepatitis B immunoglobulin and vaccine. On the other hand, with the available immunoprophylaxis, 13.8% participants mistakenly believed caesarean section may prevent HBV mother-to-child transmission, and only 13% correctly answered that newborns of HBsAg positive mothers may be breastfed. Conclusion: Obs/Gyn staff in China have mastered the strategies of HBV PMTCT, but there is obvious insufficiency in details of the application. Intensified efforts to train the Obs/Gyn staff are required to improve the current suboptimal medical service in HBV-exposed infants and to control mother-to-infant transmission of HBV.


Medicine ◽  
2018 ◽  
Vol 97 (22) ◽  
pp. e10931 ◽  
Author(s):  
Qiu-Ju Sheng ◽  
Sui-Jing Wang ◽  
Yu-Yu Wu ◽  
Xiao-Guang Dou ◽  
Yang Ding

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