scholarly journals A Randomized, Double-blind, Non-inferiority Trial of Magnesium Sulphate versus Dexamethasone for Prevention of Postoperative Sore Throat after Lumbar Spinal Surgery in the Prone Position

2015 ◽  
Vol 12 (10) ◽  
pp. 797-804 ◽  
Author(s):  
Jin Ha Park ◽  
Jae-Kwang Shim ◽  
Jong-Wook Song ◽  
Jaewon Jang ◽  
Ji Hoon Kim ◽  
...  
Keyword(s):  
Sore Throat ◽  
Prone Position ◽  
Magnesium Sulphate ◽  
Spinal Surgery ◽  
Postoperative Sore Throat ◽  
Double Blind ◽  
Lumbar Spinal Surgery ◽  
Lumbar Spinal

scholarly journals Effect of intraoperative neuromuscular blockade on postoperative sore throat and hoarseness in patients undergoing spinal surgery: a prospective observational study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Dongwook Won ◽  
Jee-Eun Chang ◽  
Hyerim Kim ◽  
Jung-Man Lee ◽  
Yoomin Oh ◽  
...  
Keyword(s):  
Tracheal Intubation ◽  
Sore Throat ◽  
Neuromuscular Blockade ◽  
Spinal Surgery ◽  
Prospective Observational Study ◽  
Neurophysiological Monitoring ◽  
Postoperative Sore Throat ◽  
Resting Tension ◽  
Lumbar Spinal Surgery ◽  
Lumbar Spinal

Abstract Intraoperative neuromuscular blockade affects the resting tension between the vocal cords. We assessed the effect of neuromuscular blockade on postoperative sore throat and hoarseness following tracheal intubation in patients undergoing lumbar spinal surgery in the prone position. Altogether, 99 patients were included; 50 patients did not receive neuromuscular blockade, and 49 patients received moderate neuromuscular blockade during the maintenance of anesthesia. Neuromuscular blockade was performed depending on the use of intraoperative neurophysiological monitoring. The number of intubation attempts, time to achieve tracheal intubation, and duration of intubation were recorded accordingly. The incidence and severity of postoperative sore throat and hoarseness was assessed at 1, 6, and 24 h after surgery. The overall cumulative incidence of postoperative sore throat (60% vs. 59%, respectively; P = 1.000) and postoperative hoarseness (68% vs. 61%, respectively; P = 0.532) did not differ between the no neuromuscular blockade and moderate neuromuscular blockade. The incidence and severity of postoperative sore throat and hoarseness was also not different between the moderate and no neuromuscular blockade at each time point after surgery. Nevertheless, the incidences of postoperative sore throat and hoarseness were quite high. Further studies investigating strategies to alleviate them are warranted accordingly.

scholarly journals Effect of Preoperative Nebulised Dexamethasone and Nebulised Magnesium Sulphate on Postoperative Sore Throat in Prone Position Surgeries- A Randomised Double-Blind Study

2021 ◽  
Author(s):  
G Manuj Kumar ◽  
BT Arish
Keyword(s):  
General Anaesthesia ◽  
Sore Throat ◽  
Prone Position ◽  
Magnesium Sulphate ◽  
Nmda Receptor Antagonist ◽  
P Value ◽  
Double Blind Study ◽  
Continuous Variables ◽  
Postoperative Sore Throat ◽  
Double Blind

Introduction: Postoperative Sore Throat (POST) is a frequently encountered complication after general anaesthesia with tracheal intubation and positional changes. Magnesium Sulphate (MgSO4) is a N-Methyl D-Aspartate (NMDA) receptor antagonist and dexamethasone is a glucocorticoid, both drugs helps in reducing POST by various mechanisms. Aim: To compare the effects of preoperative dexamethasone nebulisation vs preoperative MgSO4 nebulisation on sore throat in prone position surgeries. Materials and Methods: Eighty patients undergoing lumbar spine surgeries from October 2017 to April 2019, under general anaesthesia in prone position, were randomly allocated into two groups- A and B. Thirty minutes before surgery patients in each group were nebulised with respective drugs, dexamethasone 8 mg in group A and 250 mg of MgSO4 in group B. Haemodynamic parameters during laryngoscopy were noted. A standardised protocol for providing general anaesthesia was followed for all patients. After extubation, at 0, 4, 6 and 24 hours all patients were asked to grade POST, hoarseness and cough. The severity of POST was graded with four-point scale. Continuous variables were expressed as mean±SD and analysed using student t-test. The p-value <0.05 was considered statistically significant. Results: The overall incidence of sore throat in dexamethasone group was 37.5% and 20% in MgSO4 group. The incidence (p=0.026) and severity (p=0.011) of POST was significantly decreased in MgSO4 group at 6 hours where none of the patient had sore throat compared to dexamethasone where 15 (37.5%) of them had sore throat (p=0.026). None of the patients had cough and hoarseness in both groups. Conclusion:Nebulisation with MgSO4preoperatively significantly decreases the incidence and severity of POST when compared to dexamethasone and there was no statistically significant haemodynamic variability between the two groups.

Inguinal Hernia following Lumbar Spinal Surgery in the Prone Position: A case report

2006 ◽  
Vol 51 (2) ◽  
pp. 239
Author(s):  
Byung Moon Choi ◽  
Ji Hyun Chin ◽  
Young Kug Kim ◽  
Kyung Don Hahm ◽  
Ji Yeon Sim ◽  
...  
Keyword(s):  
Case Report ◽  
Inguinal Hernia ◽  
Prone Position ◽  
Spinal Surgery ◽  
Lumbar Spinal Surgery ◽  
Lumbar Spinal

A COMPARATIVE STUDY BETWEEN LIGNOCAINE NEBULISATION AND MAGNESIUM SULPHATE NEBULISATION FOR ATTENUATION OF POSTOPERATIVE SORE THROAT

2021 ◽  
pp. 9-11
Author(s):  
Dhiman Neogi ◽  
Sudeshna Bhar Kundu ◽  
Chaitali Biswas ◽  
Anisha Ghosh ◽  
Sourav Das
Keyword(s):  
Sore Throat ◽  
Postoperative Period ◽  
Magnesium Sulphate ◽  
Severity Score ◽  
Elective Surgery ◽  
Statistical Tests ◽  
Orotracheal Intubation ◽  
Controlled Study ◽  
Postoperative Sore Throat ◽  
Double Blind

BACKGROUND: Postoperative sore throat (POST) is a common complication following general anaesthesia (GA) with orotracheal intubation. Both magnesium sulphate nebulisation and lignocaine nebulisation have been reported to be used successfully to reduce the incidence and severity of POST. Till date, no study has been reported comparing the efcacy of these two drugs for attenuation of POST. Therefore, the aim of this study was to compare the efcacy of preoperative lignocaine nebulisation and magnesium sulphate nebulisation in reducing the incidence and severity of POSTin patients undergoing GAwith orotracheal intubation. METHODS:Aprospective, double blind, parallel group, randomised, controlled study was conducted on 96 patients, aged between 18-50 years, ASAphysical status I and II, undergoing elective surgery under GAwith orotracheal intubation. Patients were randomly allocated into two groups, group L and group M. The patients in group L (n=48) received 4% lignocaine nebulisation (3 ml) and those in group M (n=48) received isotonic magnesium sulphate nebulisation (3 ml) over 15 minutes ending 5 minutes prior to induction of GA. The patients were assessed for incidence and severity of POST, cough, hoarseness of voice and dysphagia at 5 minutes and thereafter at 1, 4, 12, 24 and 48 hours in the postoperative period. All data were compared using appropriate statistical tests. RESULTS: POST four-point scale was found to be signicantly lower in group M in comparison to group L at 5 minutes and 1 hour in the postoperative period. Hoarseness severity score and dysphagia severity score were also signicantly lower in group M at 1 hour postoperatively. CONCLUSION: In comparison to lignocaine nebulisation; magnesium sulphate nebulisation was found to be more effective to reduce the incidence and severity of POST, hoarseness of voice, and dysphagia particularly in the early postoperative period.

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