scholarly journals Buerger Disease: Pathological Changes in Elderly Patients

2021 ◽  
Vol 61 (9) ◽  
pp. 107-113
Author(s):  
Takehisa Iwai ◽  
Hiroko Kume ◽  
Shinya Koizumi ◽  
Kenichi Sakurazawa ◽  
Kaori Honma ◽  
...  
1997 ◽  
Vol XXIX (3-4) ◽  
pp. 95-97
Author(s):  
Е. A. Antipenko ◽  
L. M. Anisimova ◽  
А. V. Deryugina ◽  
А. V. Gustov ◽  
V. N. Krylov

Difficulties in treating discirculatory encephalopathy (DE) in the elderly are caused by a combination of degenerative and vascular processes, which mutually burden each other. The development of the disease against the background of natural aging of the body makes it necessary to take into account age-related changes in the reactivity of the body, a decrease in its adaptive capabilities, and a violation of the mechanisms of autoregulation [6]. This whole complex of pathological changes requires a special therapeutic approach that considers the body as a single functional system. It can be assumed that drugs of a non-specific plan will be effective, mobilizing the internal reserves of an aging organism.


Author(s):  
C. Uphoff ◽  
C. Nyquist-Battie

Fetal Alcohol Syndrone (FAS) is a syndrome with characteristic abnormalities resulting from prenatal exposure to ethanol. In many children with FAS syndrome gross pathological changes in the heart are seen with septal defects the most prevalent abnormality recorded. Few studies in animal models have been performed on the effects of ethanol on heart development. In our laboratory, it has been observed that prenatal ethanol exposure of Swiss albino mice results in abnormal cardiac muscle ultrastructure when mice were examined at birth and compared to pairfed and normal controls. Fig. 1 is an example of the changes that are seen in the ethanol-exposed animals. These changes include enlarged mitochondria with loss of inner mitochondrial membrane integrity and loss of myofibrils. Morphometric analysis substantiated the presence of these alterations from normal cardiac ultrastructure. The present work was undertaken to determine if the pathological changes seen in the newborn mice prenatally exposed to ethanol could be reversed with age and abstinence.


2006 ◽  
Vol 39 (15) ◽  
pp. 11
Author(s):  
Alfred E. Buxton ◽  
Anne B. Curtis
Keyword(s):  

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