scholarly journals Pancreas transplant in type 1 diabetes mellitus: the emerging role of islet cell transplant

2021 ◽  
Vol 26 (2) ◽  
pp. 86-91
Author(s):  
Inderpal Singh Kochar ◽  
Rakhi Jain
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Islet Cell ◽  
Pancreas Transplant ◽  
Cell Transplant

scholarly journals MECHANISMS IN ENDOCRINOLOGY: Mechanisms and evaluation of bone fragility in type 1 diabetes mellitus

2016 ◽  
Vol 174 (4) ◽  
pp. R127-R138 ◽  
Author(s):  
F S Hough ◽  
D D Pierroz ◽  
C Cooper ◽  
S L Ferrari ◽  
_ _
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Bone Fragility ◽  
Mineral Density ◽  
Good Glycaemic Control ◽  
Marrow Adiposity ◽  
Igf1 Deficiency

Subjects with type 1 diabetes mellitus (T1DM) have decreased bone mineral density and an up to sixfold increase in fracture risk. Yet bone fragility is not commonly regarded as another unique complication of diabetes. Both animals with experimentally induced insulin deficiency syndromes and patients with T1DM have impaired osteoblastic bone formation, with or without increased bone resorption. Insulin/IGF1 deficiency appears to be a major pathogenetic mechanism involved, along with glucose toxicity, marrow adiposity, inflammation, adipokine and other metabolic alterations that may all play a role on altering bone turnover. In turn, increasing physical activity in children with diabetes as well as good glycaemic control appears to provide some improvement of bone parameters, although robust clinical studies are still lacking. In this context, the role of osteoporosis drugs remains unknown.

scholarly journals Long-Term Insulin Independence in Type 1 Diabetes Mellitus Using a Simplified Autologous Stem Cell Transplant

2016 ◽  
Vol 101 (5) ◽  
pp. 2141-2148 ◽  
Author(s):  
Olga Graciela Cantú-Rodríguez ◽  
Fernando Lavalle-González ◽  
Miguel Ángel Herrera-Rojas ◽  
José Carlos Jaime-Pérez ◽  
José Ángel Hawing-Zárate ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Stem Cell ◽  
Type 1 Diabetes Mellitus ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Insulin Independence

Clinical and socio-demographic determinants of inadequate self-care in adults with type 1 diabetes mellitus: the leading role of self-care confidence

2018 ◽  
Vol 56 (2) ◽  
pp. 151-161 ◽  
Author(s):  
Rosario Caruso ◽  
Paola Rebora ◽  
Federica Dellafiore ◽  
Diletta Fabrizi ◽  
Barbara Riegel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Self Care ◽  
Leading Role

Role of free insulin-like growth factor-I in hyperglycemia in patients with type 1 diabetes mellitus

2000 ◽  
Vol 50 ◽  
pp. 417
Author(s):  
Kisho Kobayashi ◽  
Shin Amemiya ◽  
Koji Kobayashi ◽  
Mie Mochizuki ◽  
Tomoaki Sano ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Growth Factor ◽  
Type 1 Diabetes Mellitus ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Free Insulin ◽  
Growth Factor I
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