scholarly journals Enantioselective Recognition of Amino Acids by Enantiomerically Pure Calix[4]arene Carboxylic Acid or Their Diastereomerically Pure N-(1-Phenyl)­ethyl Amides

2013 ◽  
Vol 6 (3) ◽  
pp. 227-233 ◽  
Author(s):  
Elena A. Andreyko ◽  
Ivan I. Stoikov ◽  
Igor S. Antipin ◽  
Andrii O. Karpus ◽  
Anton M. Sikorsky ◽  
...  
Keyword(s):  
Amino Acids ◽  
Carboxylic Acid ◽  
Enantiomerically Pure ◽  
Enantioselective Recognition

π-Facial Selectivity in 1,3-Dipolar Cycloaddition Reactions of α-Methylidene-γ-lactone Substituted by 4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl Group in γ-Position

2002 ◽  
Vol 67 (3) ◽  
pp. 353-364 ◽  
Author(s):  
Petr Melša ◽  
Ctibor Mazal
Keyword(s):  
Double Bond ◽  
Carboxylic Acid ◽  
Nitrile Oxide ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Enantiomerically Pure ◽  
Nitrile Imine ◽  
Facial Selectivity ◽  
Excellent Selectivity

Diastereoselectivity of 1,3-dipolar cycloaddition reactions of benzyl azide, diazomethane, a nitrile oxide and a nitrile imine to α-methylidene-γ-lactone dipolarophile was effectively controlled by a bulky γ-substituent, 4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl in γ-position of the dipolarophile. The dipoles added from the less hindered face of the double bond with an excellent selectivity. Enantiomerically pure dipolarophile was prepared from the easily available (S)-5-oxotetrahydrohydrofuran-2-carboxylic acid.

Synthesis and Antibacterial Potency of 4-Methyl-2,7-dioxo-1,2,3,4,7,10- hexahydropyrido[2,3-ƒ]quinoxaline-8-carboxylic acid, Selected [a]-Fused Heterocyles and Acyclic Precursors

2007 ◽  
Vol 62 (11) ◽  
pp. 1453-1458 ◽  
Author(s):  
Yusuf M. Al-Hiari ◽  
Ali M. Qaisia ◽  
Mohammad Y.Abu Shuheil ◽  
Mustafa M. El-Abadelah ◽  
Wolfgang Voelter
Keyword(s):  
Amino Acids ◽  
Carboxylic Acid ◽  
Antibacterial Activities ◽  
Sodium Dithionite ◽  
E Coli ◽  
Pipecolinic Acid

The reaction of 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (7) with each of sarcosine and (±)-pipecolinic acid afforded the corresponding N-(4- oxoquinolin-7-yl)-α-amino acids 8 and 9. Reductive lactamization of the latter with sodium dithionite gave hexahydropyrido[2,3- f ]quinoxaline (10) and octahydrodipyrido[1,2-a : 2,3- f ]quinoxaline (11) derivatives, respectively. Compounds 8 - 11 and their homologs 1 - 6, accessible from (S)-proline, (2S, 4R)-4-hydroxyproline and (S)-tetrahydroisoquinoline-3-carboxylic acid exhibit good to excellent antibacterial activities against E. coli and S. aureus.

Chiral relay auxiliary for the synthesis of enantiomerically pure α-amino acids

1998 ◽  
pp. 659-660 ◽  
Author(s):  
Steven D. Bull ◽  
Stephen G. Davies ◽  
Simon W. Epstein ◽  
Jacqueline V. A. Ouzman
Keyword(s):  
Amino Acids ◽  
Enantiomerically Pure

ChemInform Abstract: Efficient Procedure for the Reduction of α-Amino Acids to Enantiomerically Pure α-Methylamines.

ChemInform ◽  
2000 ◽  
Vol 31 (49) ◽  
pp. no-no
Author(s):  
Dominick A. Quagliato ◽  
Patrick M. Andrae ◽  
Edward M. Matelan
Keyword(s):  
Amino Acids ◽  
Efficient Procedure ◽  
Enantiomerically Pure

Enzymatic resolution of (±)-5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and its transformations into polyfunctionalised amino acids and dipeptides

2009 ◽  
Vol 20 (16) ◽  
pp. 1940-1947 ◽  
Author(s):  
Giuseppe Cremonesi ◽  
Piero Dalla Croce ◽  
Alessandra Forni ◽  
Maddalena Gallanti ◽  
Raffaella Gandolfi ◽  
...  
Keyword(s):  
Amino Acids ◽  
Carboxylic Acid ◽  
Ethyl Ester ◽  
Acid Ethyl Ester ◽  
Enzymatic Resolution

1,3-diastereocontrol with bromoallenes. Synthesis of enantiomerically pure β-branched α-amino acids

1994 ◽  
Vol 35 (42) ◽  
pp. 7775-7778 ◽  
Author(s):  
Fabiana D'Aniello ◽  
André Mann ◽  
Maurizio Taddei ◽  
Camille-Georges Wermuth
Keyword(s):  
Amino Acids ◽  
Enantiomerically Pure
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