scholarly journals Efficient and Stereoselective Synthesis of Carbohydrateα,β-Un- saturated Esters by Microwave Assisted Wittig Reaction

2012 ◽  
Vol 32 (8) ◽  
pp. 1519
Author(s):  
Xiaoliu Li ◽  
Wei Wang ◽  
Rui Li ◽  
Pingzhu Zhang ◽  
Hua Chen
Keyword(s):  
Wittig Reaction ◽  
Stereoselective Synthesis ◽  
Microwave Assisted

scholarly journals Stereoselective Synthesis of Tetraalkyl Cyclobutene-1,2,3,4-tetracarboxylates. Synthesis of Tetraalkyl (Z,Z)-Buta-1,3-diene-1,2,3,4-tetracarboxylates

1999 ◽  
Vol 23 (8) ◽  
pp. 512-513
Author(s):  
Issa Yavari ◽  
Farahnaz Nourmohammadian
Keyword(s):  
Ring Opening ◽  
Wittig Reaction ◽  
Stereoselective Synthesis ◽  
Intramolecular Wittig Reaction ◽  
Ring Opening Reactions ◽  
Boiling Toluene

Tetraalkyl cyclobutene-1,2,3,4-tetracarboxylates, prepared by intramolecular Wittig reaction between a vinylphosphonium salt and diethyl 2-oxobutanedioate, undergo electrocyclic ring-opening reactions, in boiling toluene, to produce highly electron-deficient 1,3-dienes.

scholarly journals A microwave-assisted stereoselective synthesis of polyandrocarpamines A and B

2009 ◽  
Vol 50 (8) ◽  
pp. 880-882 ◽  
Author(s):  
Rohan A. Davis ◽  
Paul S. Baron ◽  
Juliette E. Neve ◽  
Carleen Cullinane
Keyword(s):  
Stereoselective Synthesis ◽  
Microwave Assisted

scholarly journals One-pot sequential synthesis of isocyanates and urea derivatives via a microwave-assisted Staudinger–aza-Wittig reaction

2013 ◽  
Vol 9 ◽  
pp. 2378-2386 ◽  
Author(s):  
Diego Carnaroglio ◽  
Katia Martina ◽  
Giovanni Palmisano ◽  
Andrea Penoni ◽  
Claudia Domini ◽  
...  
Keyword(s):  
Wittig Reaction ◽  
Scale Up ◽  
Alkyl Halides ◽  
Secondary Amines ◽  
Nucleophilic Substitutions ◽  
One Pot ◽  
Urea Derivatives ◽  
Step Process ◽  
Microwave Assisted ◽  
Simple Filtration

A fast and efficient protocol for the synthesis of N,N'-disubstituted urea derivatives from alkyl halides and primary or secondary amines has been developed. The synthetic pathway combines nucleophilic substitutions and a Staudinger–aza-Wittig reaction in the presence of polymer-bound diphenylphosphine under 14 bar of CO2 pressure and has been performed in a one-pot two-step process. The protocol has been optimized under microwave irradiation and the scale-up experiment has been conducted under conventional conditions in a Parr reactor. The final compounds were isolated after simple filtration in almost quantitative overall yields which makes this procedure facile and rapid to execute.

ChemInform Abstract: Stereoselective Synthesis of Racemic and Optically Active E-Vinyl and E-Dienyl Sulfoxides via Wittig Reaction of α-Sulfinyl Phosphonium Ylides.

ChemInform ◽  
2010 ◽  
Vol 30 (22) ◽  
pp. no-no
Author(s):  
Marian Mikolajczyk ◽  
Wieslawa Perlikowska ◽  
Jan Omelanczuk ◽  
Henri-Jean Cristau ◽  
Anne Perraud-Darcy
Keyword(s):  
Wittig Reaction ◽  
Stereoselective Synthesis ◽  
Optically Active

scholarly journals Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation

2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Adriana V. Treuer ◽  
Pedro De-La-Torre ◽  
Margarita I. Gutiérrez
Keyword(s):  
Mass Spectrometry ◽  
Broad Spectrum ◽  
Electrospray Mass Spectrometry ◽  
Stereoselective Synthesis ◽  
Knoevenagel Condensation ◽  
Knoevenagel Reaction ◽  
Microwave Assisted ◽  
C Nmr

Given the broad spectrum of biological uses of heteroaryl-acrylonitrile derivatives, it is necessary to find simple methods to synthesize and diversify this family of compounds. We report a stereoselective synthesis of a series of new (E)-2-(1H-indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles (3a–3i) obtained from 3-(cyanoacetyl)indole and heteroaryl-aldehydes under microwave-assisted Knoevenagel reaction at 300 W of potency and 100°C. The desired derivatives (3a–3i) were obtained with variable yields (30–94%) and time reactions (8–90 min). All the heteroaryl-acrylonitriles were characterized by physicoanalytical techniques such IR, 1H, 13C NMR, and electrospray mass spectrometry.

Sign in / Sign up

Export Citation Format

Share Document