Research Progress in Functional Metal-Organic Frameworks for Tumor Therapy

2019 ◽  
Vol 77 (11) ◽  
pp. 1156
Author(s):  
Jinyue Zeng ◽  
Xiaoshuang Wang ◽  
Xianzheng Zhang ◽  
Renxi Zhuo
Keyword(s):  
Tumor Therapy ◽  
Metal Organic Frameworks ◽  
Research Progress ◽  
Metal Organic

scholarly journals Environment Responsive Metal–Organic Frameworks as Drug Delivery System for Tumor Therapy

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Chao Yan ◽  
Yue Jin ◽  
Chuanxiang Zhao
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Tumor Therapy ◽  
Metal Organic Frameworks ◽  
Delivery Systems ◽  
Drug Uptake ◽  
High Concentration ◽  
Metal Organic

AbstractNanoparticles as drug delivery systems can alter the drugs' hydrophilicity to affect drug uptake and efflux in tissues. They prevent drugs from non-specifically binding with bio-macromolecules and enhance drug accumulation at the lesion sites, improving therapy effects and reducing unnecessary side effects. Metal–organic frameworks (MOFs), the typical nanoparticles, a class of crystalline porous materials via self-assembled organic linkers and metal ions, exhibit excellent biodegradability, pore shape and sizes, and finely tunable chemical composition. MOFs have a rigid molecular structure, and tunable pore size can improve the encapsulation drug's stability under harsh conditions. Besides, the surface of MOFs can be modified with small-molecule ligands and biomolecule, and binding with the biomarkers which is overexpressed on the surface of cancer cells. MOFs formulations for therapeutic have been developed to effectively respond to the unique tumor microenvironment (TEM), such as high H2O2 levels, hypoxia, and high concentration glutathione (GSH). Thus, MOFs as a drug delivery system should avoid drugs leaking during blood circulation and releasing at the lesion sites via a controlling manner. In this article, we will summary environment responsive MOFs as drug delivery systems for tumor therapy under different stimuli.

Carbon Dioxide Captured by Metal Organic Frameworks and Its Subsequent Resource Utilization Strategy: A Review and Prospect

2019 ◽  
Vol 19 (6) ◽  
pp. 3059-3078 ◽  
Author(s):  
Xinbo Lian ◽  
Leilei Xu ◽  
Mindong Chen ◽  
Cai-e Wu ◽  
Wenjing Li ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Resource Utilization ◽  
Power Plants ◽  
Energy Requirement ◽  
Metal Organic Frameworks ◽  
Research Progress ◽  
Zeolitic Imidazolate Frameworks ◽  
Wide Range ◽  
Metal Organic ◽  
And Storage

The carbon dioxide (CO2) is notorious as the greenhouse gas, which could cause the global warming and climate change. Therefore, the reduction of the atmospheric CO2 emissions from power plants and other industrial facilities has become as an increasingly urgent concern. In the recent years, CO2 capture and storage technologies have received a worldwide attention. Adsorption is considered as one of the efficient options for CO2 capture because of its cost advantage, low energy requirement and extensive applicability over a relatively wide range of temperature and pressure. The metal organic frameworks (MOFs) show widely potential application prospects in CO2 capture and storage owing to their outstanding textural properties, such as the extraordinarily high specific surface area, tunable pore size, ultrahigh porosity (up to 90%), high crystallinity, adjustable internal surface properties, and controllable structure. Herein, the most important research progress of MOFs materials on the CO2 capture and storage in recent years has been comprehensively reviewed. The extraordinary characteristics and CO2 capture performance of Zeolitic Imidazolate Frameworks (ZIFs), Bio-metal organic frameworks (bio-MOFs), IL@MOFs and MOF-composite materials were highlighted. The promising strategies for improving the CO2 adsorption properties of MOFs materials, especially the low-pressure adsorption performance under actual flue gas conditions, are also carefully summarized. Besides, CO2 is considered as an abundant, nontoxic, nonflammable, and renewable C1 resource for the synthesis of useful chemicals and fuels. The potential routes for resource utilization of the captured CO2 are briefly proposed.

scholarly journals Research Progress of Metal-Organic Frameworks Based Antibacterial Materials

2020 ◽  
Vol 78 (7) ◽  
pp. 613 ◽  
Author(s):  
Ye Qi ◽  
Shuangsong Ren ◽  
Ying Che ◽  
Junwei Ye ◽  
Guiling Ning
Keyword(s):  
Metal Organic Frameworks ◽  
Research Progress ◽  
Antibacterial Materials ◽  
Metal Organic

Research progress on nanoporous carbons produced by the carbonization of metal organic frameworks

Carbon ◽  
2021 ◽  
Vol 179 ◽  
pp. 702
Author(s):  
Qian Zhang ◽  
Chun-feng Xue ◽  
Jin-xin Wang ◽  
Rui-chao Huang ◽  
H.A.O. Xiao-gang ◽  
...  
Keyword(s):  
Metal Organic Frameworks ◽  
Research Progress ◽  
Nanoporous Carbons ◽  
Metal Organic

scholarly journals Research progress on catalytic performance of metal organic frameworks for direct methane conversion

2020 ◽  
Vol 51 (2) ◽  
pp. 165-174
Author(s):  
Zhen Zhao ◽  
Hang Zhang ◽  
Sisi Zhao ◽  
Baiming Zhang ◽  
Chenyang Yue
Keyword(s):  
Methane Conversion ◽  
Metal Organic Frameworks ◽  
Catalytic Performance ◽  
Research Progress ◽  
Metal Organic

scholarly journals Research Progress of High-throughput Computational Screening of Metal-Organic Frameworks

2019 ◽  
Vol 77 (4) ◽  
pp. 323
Author(s):  
Zhilu Liu ◽  
Wei Li ◽  
Hao Liu ◽  
Xudong Zhuang ◽  
Song Li
Keyword(s):  
High Throughput ◽  
Metal Organic Frameworks ◽  
Research Progress ◽  
Computational Screening ◽  
Metal Organic

Recent progress in lanthanide metal–organic frameworks and their derivatives in catalytic applications

2021 ◽  
Author(s):  
Yue Zhang ◽  
Shuo Liu ◽  
Zi-Song Zhao ◽  
Zengfang Wang ◽  
Ruiying Zhang ◽  
...  
Keyword(s):  
Recent Progress ◽  
Metal Organic Frameworks ◽  
Organic Reactions ◽  
Research Progress ◽  
Metal Organic ◽  
Lanthanide Metal ◽  
Catalytic Applications

Research progress in lanthanide metal–organic frameworks and their derivatives in the field of catalysis has been presented on the basis of different organic reactions.

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