scholarly journals Epithelial and bone tissue mast cell populations in the female rat as influenced by calcium and vitamin D deficiencies, ovariectomy, and estrogen / by Rogene Tesar.

1982 ◽  
Author(s):  
Rogene Tesar
Keyword(s):  
Vitamin D ◽  
Mast Cell ◽  
Bone Tissue ◽  
Cell Populations ◽  
Female Rat ◽  
Tissue Mast Cell

Vitamin D Effects on Guided Bone Regeneration and Osseointegration of Dental Implants (Literature Review)

2020 ◽  
Vol 75 (5) ◽  
pp. 552-560
Author(s):  
Sergey Yu. Ivanov ◽  
Svetlana Yu. Kalinchenko ◽  
Nidjat A. Guseynov ◽  
Aleksander A. Muraev ◽  
Aigul Т. Safi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Tissue ◽  
Dental Implants ◽  
Scientific Data ◽  
Reparative Regeneration ◽  
Jaw Bone ◽  
Dental Implantation ◽  
Oral Reconstruction ◽  
Phosphate Exchange ◽  
Regeneration Of Bone

Background.Due to the prevalence of Vitamin D deficiency as well as the frequency of reconstructive surgical interventions followed by dental implantation, the issue arises concerning the effect of Vitamin D on reparative regeneration of bone and osseointegration of dental implants.The purpose using literature data we are conducting an impact assessment of vitamin D on reparative regeneration of bone tissue, in particular, after oral reconstruction surgeries and dental implantation.Methods.Retrieval, systematization and analysis of scientific data on application of vitamin D supplementation and its effect on reparative regeneration of jaw bone tissue.The conclusions.For the most part, the positive effect exerted on reparative regeneration of jaw bone tissue and osseointegration of dental implants is due to the role of vitamin D in physiological processes evolving in bone tissue, namely maintenance of calcium and phosphate exchange through intestinal absorption and TNF, RANKL (Receptor activator of nuclear factor kappa-B ligand) and consequently differentiation of precursors to osteoclasts into osteoclasts through VDR stimulation (VitaminD Receptor) receptors for further osteogenesis. Also, according to literature data, FGF23 (Fibroblast Growth Factor) protein is a marker of osteoblasts differentiation into osteocytes, it is also known that FGF23 and 1,25(ОН)2D3 are genetically related. FGF23 is the main regulator of both phosphate exchange in bones and metabolism of vitamin D and its metabolites. Besides, indirect anti-inflammatory effect has been observed thanks to inhibition of pro-inflammatory cytokine secretion. Taking into account the abovementioned data, of particular relevance is the definition of serum concentration 25(ОН)D and development of schemes of vitamin D level pre-surgery correction in patients, who have to undergo oral reconstruction surgeries and dental implantation. Mass spectrometry is a promising diagnostic method for determining the level of vitamin D in a body, as it allows to identify the actual amount of vitamin D free from admixture of other steroid hormones. The introduction of this method into clinical practice will allow to monitor the level of vitamin D in patients, receiving reconstructive and rehabilitative treatment.

scholarly journals Studies of connective tissue mast cell-mediated cytotoxicity

1989 ◽  
Vol 93 (3) ◽  
pp. 423-428 ◽  
Author(s):  
Michael D. Tharp ◽  
Candace Kasper ◽  
Dwain Thiele ◽  
Michael R. Charley ◽  
Donald A. Kennerly ◽  
...  
Keyword(s):  
Mast Cell ◽  
Connective Tissue ◽  
Tissue Mast Cell

scholarly journals Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

Blood ◽  
1988 ◽  
Vol 72 (3) ◽  
pp. 877-885 ◽  
Author(s):  
Y Kanakura ◽  
H Thompson ◽  
T Nakano ◽  
T Yamamura ◽  
H Asai ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Tissue Type ◽  
Cell Populations ◽  
Proliferative Potential ◽  
Heparin Binding ◽  
Peritoneal Mast Cells ◽  
Proliferative Ability

Mouse peritoneal mast cells (PMC) express a connective tissue-type mast cell (CTMC) phenotype, including reactivity with the heparin-binding fluorescent dye berberine sulfate and incorporation of [35S] sulfate predominantly into heparin proteoglycans. When PMC purified to greater than 99% purity were cultured in methylcellulose with IL-3 and IL-4, approximately 25% of the PMC formed colonies, all of which contained both berberine sulfate-positive and berberine sulfate-negative mast cells. When these mast cells were transferred to suspension culture, they generated populations that were 100% berberine sulfate-negative, a characteristic similar to that of mucosal mast cells (MMC), and that synthesized predominantly chondroitin sulfate [35S] proteoglycans. When “MMC-like” cultured mast cells derived from WBB6F1-+/+ PMC were injected into the peritoneal cavities of mast cell-deficient WBB6F1- W/Wv mice, the adoptively transferred mast cell population became 100% berberine sulfate-positive. In methylcellulose culture, these “second generation PMC” formed clonal colonies containing both berberine sulfate-positive and berberine sulfate-negative cells, but exhibited significantly less proliferative ability than did normal +/+ PMC. Thus, clonal mast cell populations initially derived from single PMC exhibited multiple and bidirectional alterations between CTMC-like and MMC-like phenotypes. However, this process was associated with a progressive diminution of the mast cells' proliferative ability.

Relationship between Vitamin D Levels and Bone Tissue in Adolescents with and without Down Syndrome

2017 ◽  
Vol 29 (4) ◽  
pp. 611-624
Author(s):  
Ángel Matute-Llorente ◽  
Alejandro González-Agüero ◽  
Luis A. Moreno-Aznar ◽  
Germán Vicente-Rodríguez ◽  
José A. Casajús
Keyword(s):  
Vitamin D ◽  
Down Syndrome ◽  
Bone Tissue ◽  
Vitamin D Levels

Mo1237 ESTABLISHMENT OF NORMAL TISSUE MAST CELL LEVELS IN GASTRIC AND DUODENAL BIOPSIES OF PATIENTS WTHOUT GASTROINTESTINAL DISEASE

2020 ◽  
Vol 158 (6) ◽  
pp. S-839
Author(s):  
Craig C. Reed ◽  
Robert M. Genta ◽  
Bradford Youngblood ◽  
Alan T. Chang ◽  
Amol P. Kamboj ◽  
...  
Keyword(s):  
Mast Cell ◽  
Normal Tissue ◽  
Gastrointestinal Disease ◽  
Tissue Mast Cell ◽  
Duodenal Biopsies

scholarly journals Multiple cutaneous mast cell tumours in a Boa imperator

2020 ◽  
Vol 8 (1) ◽  
pp. e001040
Author(s):  
Ann-Kathrin Onkels ◽  
Christina Stadler ◽  
Udo Hetzel ◽  
Jana Mueller ◽  
Christiane Herden
Keyword(s):  
Mast Cell ◽  
Subcutaneous Tissue ◽  
Skin Lesions ◽  
Giemsa Stain ◽  
Cell Populations ◽  
Round Cell ◽  
Dense Granules ◽  
The Family ◽  
Cutaneous Mast Cell ◽  
Metachromatic Granules

Mast cell tumours (MCTs) are common in dogs and cats, but are only rarely reported in reptiles. This case documents the clinical and pathomorphological results from a Boa imperator with multiple cutaneous nodules, diagnosed as MCT based on histopathology, immunohistochemistry and electron microscopy approaches. Grossly, there were multifocal, poorly demarcated, mostly ulcerated nodules ~3 cm in diameter on the skin. Histologically, the dermis and the subcutaneous tissue were infiltrated by round cell populations with eosinophilic granules. Toluidine blue and Giemsa stain revealed metachromatic granules. Using immunohistochemistry, some cells exhibited cytoplasmic immunostaining positive for tryptase. Ultrastructurally, variable quantities of intracytoplasmic, spherical and electron-dense granules were also detected. The MCT literature on snakes is scarce, especially for the family Boidae, but MCTs should be considered a differential diagnosis for nodular skin lesions in reptiles.

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