scholarly journals Drug-development Strategy for Undruggable Targets Using a Novel Target Degradation Technology CANDDY

2022 ◽  
Vol 22 (0) ◽  
pp. 19-24
Author(s):  
Etsuko Miyamoto-Sato ◽  
Satoshi Imanishi ◽  
Lijuan Huang
Keyword(s):  
Drug Development ◽  
Development Strategy ◽  
Novel Target

Drug development in IBD: from novel target identification to early clinical trials

Gut ◽  
2016 ◽  
Vol 65 (8) ◽  
pp. 1233-1239 ◽  
Author(s):  
Silvio Danese ◽  
Claudio Fiocchi ◽  
Julián Panés
Keyword(s):  
Clinical Trials ◽  
Drug Development ◽  
Target Identification ◽  
Novel Target

Human pregnane X receptor: a novel target for anticancer drug development

2014 ◽  
Vol 19 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Vijay Rathod ◽  
Sumit Jain ◽  
Prajwal Nandekar ◽  
Abhay T. Sangamwar
Keyword(s):  
Drug Development ◽  
Anticancer Drug ◽  
Pregnane X Receptor ◽  
Novel Target ◽  
Anticancer Drug Development

scholarly journals Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy

2015 ◽  
Vol 28 (10) ◽  
pp. 1914-1925 ◽  
Author(s):  
Bie M. P. Verbist ◽  
Geert R. Verheyen ◽  
Liesbet Vervoort ◽  
Marjolein Crabbe ◽  
Dominiek Beerens ◽  
...  
Keyword(s):  
Image Analysis ◽  
Drug Development ◽  
Development Strategy ◽  
High Dimensional ◽  
Proof Of Concept ◽  
Analysis Tools ◽  
Early Drug

scholarly journals Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?

2018 ◽  
Vol 13 (2) ◽  
pp. 224 ◽  
Author(s):  
Jérôme Braudeau ◽  
Benoit Souchet ◽  
Mickael Audrain ◽  
Baptiste Billoir ◽  
Laurent Lecanu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Development ◽  
Development Strategy ◽  
Silent Phase

scholarly journals Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development

Virology ◽  
2017 ◽  
Vol 507 ◽  
pp. 32-39 ◽  
Author(s):  
Nopporn Chutiwitoonchai ◽  
Takafumi Mano ◽  
Michinori Kakisaka ◽  
Hirotaka Sato ◽  
Yasumitsu Kondoh ◽  
...  
Keyword(s):  
Drug Development ◽  
Nuclear Export ◽  
Influenza A ◽  
Antiviral Drug ◽  
Nuclear Export Protein ◽  
Novel Target ◽  
Export Protein
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