scholarly journals Limberg flap as simplest solution for covering skin defects of different sizes and localizations

2020 ◽  
Vol 11 (2) ◽  
pp. 188-194
Author(s):  
Siniša Kojić ◽  
Zuhra Memić ◽  
Vera Sabljak ◽  
Helena Marić-Kujundžić ◽  
Bojan Kujundžić ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Late Complication ◽  
University Hospital ◽  
Limberg Flap ◽  
Lumbosacral Region ◽  
Transposition Flap ◽  
Basic Principles ◽  
The Face ◽  
Case Presentations ◽  
The University

Introduction. Whether it is a classic version of the flap or its modification, the Limberg flap is an appropriate solution for covering small and medium-sized defects, as well as for covering largesized defects where certain localizations are concerned. It represents a local, transposition flap that has proven to be a safe option. Methods. The defect coverage was achieved by marking a defect that was in the form of an equilateral rhombus by means of extending a shorter diagonal by the length of its side and drawing a parallel with the defect side, which created four different flaps. We included 50 patients surgically treated at the Varis Clinic for Plastic and Reconstructive Surgery in Belgrade and the University Hospital in Foca for the period 2018-2020. In all patients, we used the Limberg flap as a method for defect reconstruction. Case presentations. The sample was comprised of up to 50 patients, with an average respondent age of 60.3 years. According to etiology, the most common changes in the skin belonged to Basal cell carcinoma (58%), Squamous cell carcinoma (24%) and melanoma (8%), with the most common predilection sites associated with the face in 22 patients and with the lumbosacral region in 8 patients. A well-planned Limberg flap caused minor complications in terms of mild marginal infection in one patient, and mild marginal infection as an early complication and a stretched scar as a late complication in one patient as well. Other complications in the sample were not recorded. Conclusion. To obtain the best possible functional and esthetic result with minimal disruption of the region, respecting the anatomy and the basic principles in plastic surgery, the Limberg flap is an excellent solution for the reconstruction of defects of different sizes.

scholarly journals Advanced basal cell carcinomas of the face: A Moroccan series

2021 ◽  
Vol 12 (2) ◽  
pp. 135-139
Author(s):  
Sara Elloudi ◽  
Aida Oulehri ◽  
Hanane Baybay ◽  
Zakia Douhi ◽  
Fatima Zahra Mernissi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Rural Areas ◽  
University Hospital ◽  
Temporal Region ◽  
Dermatology Department ◽  
Skin Malignancy ◽  
The Face ◽  
The University

Background: Basal cell carcinoma (BCC) is the most common cutaneous skin malignancy. 85% of BCCs affect the face, a region particularly rich in noble organs. Although BCC progresses slowly, considerable local destruction and mutilation may be observed. Material and Methods: We performed a retrospective review of the database stored by our institution. All patients with histologically confirmed mutilating basal cell carcinoma of the face hospitalized at the dermatology department of the university hospital in Fez, Morocco, from 2015 through 2020 were evaluated. Results: Nine patients were included, with the tumors located in the lips, temporal region, orbital region, and cheeks, with sizes varying from 5 to 11 cm. Conclusion: In the series, we were able to highlight the high-risk character of the subpopulation living in rural areas and the role of smoking as a major risk factor.

scholarly journals Epidemiological, Clinical, and Paraclinic Aspect of Cutaneous Sarcoidosis in Black Africans

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Mamadou Kaloga ◽  
Ildevert Patrice Gbéry ◽  
Vagamon Bamba ◽  
Yao Isidore Kouassi ◽  
Elidjé Joseph Ecra ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
University Hospital ◽  
Time Interval ◽  
Cutaneous Sarcoidosis ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Dermatology Department ◽  
Respiratory Involvement ◽  
The Face ◽  
The University

The specific objectives were to identify the epidemiology of cutaneous sarcoidosis and describe the clinical and laboratory aspects of the disease.Materials and Methods. We performed a descriptive cross-sectional study involving 24 referred cases of cutaneous sarcoidosis in 25 years (1990–2014) collected at Venereology Dermatology Department of the University Hospital of Treichville (Abidjan) both in consultation and in hospitalization.Results. The hospital frequency was one case per year. The average age was 42 years, ranging from 9 to 64. The sex ratio was 1. The shortest time interval between the appearance of the skin lesion and consultation of Dermatology Department at CHU Treichville was 3 months. The elementary lesions were represented primarily by a papule (18 cases), placard (3 cases), and nodule (2 cases) and mainly sat on the face and neck in 8 cases (38%). Extra cutaneous lesions were dominated by ganglion and respiratory involvement with 5 cases each followed by musculoskeletal damage in 3 cases. Chest radiography showed abnormality in 13 cases (54%). The pulmonary function test performed in 13 patients found 7 cases (54%) having restrictive ventilatory syndrome and 6 cases (46%) being normal. A tuberculin anergy was found in 11 cases (61%).

A single institution retrospective analysis of basosquamous carcinoma of the head and neck

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 15530-15530 ◽  
Author(s):  
P. Clement ◽  
J. Verheezen ◽  
S. Nuyts ◽  
V. Vanderpoorten ◽  
R. Sciot
Keyword(s):  
Overall Survival ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Lymph Node Involvement ◽  
University Hospital ◽  
Base Of Tongue ◽  
Node Involvement ◽  
The University

15530 Background: Basosquamous Cell Carcinoma (BSCC) of the larynx, hypopharynx and base of tongue represents 1% of all head and neck tumours. It is considered a more aggressive disease than squamous cell carcinoma, based on higher incidence of advanced stage disease (60% lymph node-involvement and 40% metastases at diagnosis). Therefore, a treatment regimen including chemotherapy is often recommended in addition to surgery and/or radiotherapy in the literature. Methods: We retrospectively analyzed the data of all patients diagnosed with BSCC of the head and neck at the University Hospital of Leuven between 1993 and 2003, and report here the stage at diagnosis, treatment modality, disease evolution, progression free and overall survival. Results: Seven patients where diagnosed with BSCC in the head and neck region. Six patients were male. Three of the tumours were localised in the larynx, two at the base of tongue, and two in the oral cavity. The AJCC stages of disease ranged from I to IVa. Three patients had lymph node involvement at diagnosis. Six patients were treated with surgery in combination with radiotherapy. One patient was treated with cryotherapy before brachytherapy was applied. Five patients have no evidence of disease with a follow up of 4, 5, 6, 10 and 11 years, respectively. One patient died of an unknown cause 18 months after treatment. Only one of the seven patients, developed metastases during follow up. This patient had BSCC of the base of tongue, and was diagnosed with lungmetastases 16 months after surgery and radiotherapy. He was treated with the combination of Doxorubicine, Cisplatin and Fluorouracil. A partial response was confirmed after six cycles. Eight months after the last treatment cycle, there is still no evidence of disease progression. Conclusions: BSCC is a rare tumour of the head and neck. Seven patients were treated at the University hospital of Leuven in the period between 1993 and 2003 with a median progression free and overall survival of more than 5 years. Only one patient developed metastases, and was consequently treated with chemotherapy, inducing a continuing partial remission 8 months after treatment. In contrast to what is reported in the literature we do not confirm a high incidence of metastases at diagnosis nor a high mortality rate. No significant financial relationships to disclose.

scholarly journals Radiotherapy in Periocular Cutaneous Malignancies: A Retrospective Study

Dermatology ◽  
2019 ◽  
Vol 235 (3) ◽  
pp. 234-239 ◽  
Author(s):  
Diana Lazarevic ◽  
Egle Ramelyte ◽  
Reinhard Dummer ◽  
Laurence Imhof
Keyword(s):  
Cell Carcinoma ◽  
Therapeutic Response ◽  
University Hospital ◽  
X Rays ◽  
Lentigo Maligna ◽  
Safety And Efficacy ◽  
Time To Recurrence ◽  
Therapy Option ◽  
The University

Background: Due to the importance of function and cosmetics, periocular skin malignancies represent a therapeutic challenge. Objective: To evaluate the safety and efficacy of radiotherapy (RT) treating periocular skin tumors. Methods: Data of patients with periocular tumors treated with grenz or soft X-rays at the University Hospital Zurich, Switzerland, between 2009 and 2014 were reviewed. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) with associated in situ lesions, cutaneous melanoma, lentigo maligna (LM), cutaneous lymphoma and Kaposi’s sarcoma were included in the analysis. Results: We found 159 periocular lesions in 145 patients. Overall recurrence was highest for actinic keratosis and Bowen’s disease (27%), melanoma (17%) and LM (15%), whereas SCC and BCC showed recurrence in 11 and 10%, respectively. 45% of all recurrences occurred within 12 months after treatment, with a median time to recurrence of 13 months (range 3–73). Conclusion: RT, which provides a good therapeutic response with minimal adverse events, is a therapy option for periocular cutaneous malignancies.

GENETIC STUDIES ON THE CONGENITALLY HYPOTHYROID

PEDIATRICS ◽  
1961 ◽  
Vol 27 (2) ◽  
pp. 269-285
Author(s):  
James V. Neel ◽  
Edward A. Carr ◽  
William H. Beierwaltes ◽  
Ruth T. Davidson
Keyword(s):  
Congenital Hypothyroidism ◽  
Present Report ◽  
University Hospital ◽  
Endocrine Disorders ◽  
Genetic Studies ◽  
Thyroid Glands ◽  
Comprehensive Picture ◽  
The Face ◽  
The University ◽  
Index Cases

THE IMPORTANCE of congenital hypothyroidism as a cause of human disability varies greatly from one part of the world to another, bearing a well-known relationship to the availability of dietary iodine. However, even in areas where the iodine supply is adequate, or in areas of endemic cretinism where iodized salt has been introduced, severe hypothyroidism remains one of the important endocrine disorders of childhood. The present report is concerned with the genetic aspects of an attempt to obtain a comprehensive picture of congenital hypothyroidism in the state of Michigan at the present time. Recent advances in techniques for the study of thyroid disease, as well as the even earlier recognition and treatment of congenital hypothyroidism, have rendered obsolescent, in nonendemic areas, the traditional division of cretins into goitrous and nongoitrous or athyrotic. Thus, current techniques permit the recognition of minute or ectopic thyroid glands in the former "athyrotic" group while prompt recognition and treatment of congenital hypothyroidism may forestall, at least temporarily, the development of a goiter in a potentially "goitrous cretin," and even conceivably, in the face of long continued therapy, lead to the degeneration to a small remnant of a thyroid which in the absence of treatment would have assumed immense proportions. Further, as brought out in the summary of Wilkins et al. the goiter of a "goitrous cretin" not infrequently fails to appear before the second decade; a study at the age level of the present one accordingly cannot rely on physical examination alone for a classification. There is thus the need for an extremely careful use of both terms and techniques in any over-all approach to congenital hypothyroidism such as this purports to be. SUBJECTS The present report stems from genetic studies on 54 index cases (propositi) with severe hypothyroidism, representing 50 sibships. These persons were located in the following manner: 1) Through a review of the charts of all patients on whom the diagnosis of congenital hypothyroidism was made at the University Hospital between 1930 and 1959. This review yielded a total of 54 diagnosed cases, of whom 28 in 26 sibships are included in the present series. The remaining 26 cases are not included in the study for the following reasons: a) laboratory and other studies not yet complete on 14 patients, b) 5 patients either live out of state or cannot be located, c) diagnosis not confirmed in 2 cases, d) 2 patients deceased, and e) family unable to cooperate in 3 cases.

scholarly journals Giant Orbital Melanoma in a Heroin Abuser

2017 ◽  
Vol 8 (1) ◽  
pp. 288-293 ◽  
Author(s):  
Alena Furdova ◽  
Pavel Babal
Keyword(s):  
Biopsy Specimen ◽  
Histopathological Examination ◽  
Palliative Therapy ◽  
University Hospital ◽  
Solid Mass ◽  
Emergency Center ◽  
The Face ◽  
History Of ◽  
The Right ◽  
The University

Purpose: The aim of this report was to report a heroin abuser with nondiagnosed giant uveal melanoma infiltrating the orbit and prolapsing through the face. Methods: We conducted a case report of the patient with giant melanoma. Results: In March 2013, a 39-year-old male with bleeding from the right side of his face was taken to the Emergency Center of the University Hospital Bratislava by ambulance. The heroin abusing, homeless male who had never been treated before reported a 2-year history of a prolapsed, dark colored mass from his eye. Acute computed tomography confirmed a solid mass 20 × 20 cm prolapsing from the orbit. The patient rejected primary care, accepted only 1 transfusion and left the hospital. Two months later, he was admitted to the hospital due to anemia after many collapses. Liver metastasis was present. Surgical palliative therapy was not possible due to his general status. The patient started fractionated external radiotherapy with 8.0 Gy Co60. Histopathological examination of the biopsy specimen showed malignant melanoma of the epitheloid type G2–3. The patient died in December 2013. Conclusion: Extraorbital formation of a melanoma mass may progress to a giant volume, and without treatment, led to metastases in the liver and to death after 9 months in our patient with anemia.

scholarly journals Primitive Ocular Cancers in the University Hospital of Brazzaville

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Young Adults ◽  
Cell Carcinoma ◽  
Developed Countries ◽  
Sebaceous Carcinoma ◽  
Health Science ◽  
University Hospital ◽  
East African ◽  
Black Africa ◽  
Uveal Tract ◽  
The University

Introduction: With the exception of retinoblastoma and melanoma of the uveal tract, primitive ocular cancers originate from the accessory structures of the eye, especially the eyelids and the conjunctiva. While in developed countries these cancers are mostly encountered after 60 years, in black Africa their prevalence has increased in young adults. Objective: To determine the epidemiological, clinical and histological profile of these tumors in the University Hospital of Brazzaville. Methodology: Mini analysis of nine (9) of our publications, published between 2015 and 2017, in the journals: East African Medical Journal, Health Science and Diseases, EC Ophthalmology, and Revue de Médecine et de Pharmacie. HIV serology has been systematically requested except for cases of retinoblastoma. Histological evidence was made in all cases. Results: 86 patients had been seen. Average age 31.2 years (2 years - 75 years), sex ratio equal to 1.08. Reasons for consultation: exophthalmia (44), mass (35%), leucocoria (20%) and palpebral wounds (1%). Affected structures: conjunctiva (38%), retina (35%) and eyelid (27%). Histological types: squamous cell carcinoma (55.5%), retinoblastoma (25.9%), basal cell carcinoma (8.5%), sebaceous carcinoma (5.5%), Kaposia’s sarcoma (3.5%) and acral melanoma lentiginous (1.1%). HIV serology was positive in 38% overall, but in 100% of conjunctival cancers. Conclusion: Primitive ocular cancers are dominated in children by retinoblastoma. In young adults, these are essentially opportunistic cancers in the context of HIV / AIDS.

scholarly journals Osteomyelitis of the face: clinicopathological study of a 15 year old database at the University Hospital of Yaound

2021 ◽  
pp. 100097
Author(s):  
Ntep Ntep David Bienvenue ◽  
Bola Siafa Antoine ◽  
Kenna Ernest ◽  
Zilefac Ngokwe Brain ◽  
Nokam Kamdem Gimel Stéphane J ◽  
...  
Keyword(s):  
University Hospital ◽  
Clinicopathological Study ◽  
The Face ◽  
The University
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