scholarly journals Nutrition as risk factor for development of chronic non-communicable diseases

2020 ◽  
Vol 11 (1) ◽  
pp. 44-53
Author(s):  
Vesna Lazić ◽  
Biljana Mijović ◽  
Miloš Maksimović

Chronic non-communicable diseases are diseases that arise as a response of the human body to a number of factors, the most important of which are ecological and socio-economic factors. According to the World Health Organization, their classification is based on mortality and morbidity statistics. The top four leading causes of death are as follows: cardiovascular diseases, malignancies, chronic respiratory diseases and diabetes. Non-communicable diseases (NCDs) present a global public health problem, leading to over 40 million deaths a year, whereby the population aged 30 to 69 years account for one third of the total number of deaths. Risk factors for the development of chronic NCDs can be divided into metabolic and environmental ones. Metabolic risk factors include hypertension, hyperglycemia, hyperlipidemia and obesity. Environmental risk factors include: alcohol and tobacco consumption, followed by physical inactivity and unhealthy diet. Unhealthy diet, apart from posing a risk for the development of NCDs, is also the cause of metabolic risk factor development, namely hypertension and obesity. The world nutritional authorities are focused on making dietary recommendations to prevent the rising trend and subsequently reduce morbidity from NCDs.

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e049565
Author(s):  
Tilahun Tewabe Alamnia ◽  
Wubshet Tesfaye ◽  
Solomon Abrha ◽  
Matthew Kelly

ObjectivesNon-communicable diseases (NCDs) are causing a new and yetsignificant health challenge in low-income countries. In Ethiopia, although 39% of deaths are NCD related, the health system remains underprepared, highlighting the clear need for evidence on risk factor distributions to inform resource planning and the health response. Therefore, this review investigates prevalence distributions and sex and age variations of metabolic risk factors among Ethiopian adults.Research design and methodsThis systematic review used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies published until 6 January 2021 were searched from PubMed, Scopus, ProQuest and Web of Science databases, reference lists of selected studies and grey literature. Studies reporting prevalence of metabolic risk factors: overweight/obesity, hypertension, impaired glucose homoeostasis and metabolic syndrome among Ethiopian adults were eligible for this systematic review and meta-analysis. Two authors independently extracted data and used the Joanna Briggs Institute tool for quality appraisal. The random effects model was used to conduct meta-analysis using Stata V.16. Subgroup analyses examined prevalence differences by region, study year, sample size and settings.ResultsFrom 6087 records, 74 studies including 104 382 participants were included. Most showed high prevalence of metabolic risk factors. Meta-analysis revealed pooled prevalence of metabolic risk factors from 12% to 24% with the highest prevalence observed for overweight/obesity (23.9%, 95% CI 19.9% to 28.0%) and hypertension (21.1%, 95% CI 18.7% to 23.5%), followed by metabolic syndrome (14.7%, 95% CI 9.8% to 19.6%) and impaired glucose tolerance (12.4%, 95% CI 8.7% to 16.1%). The prevalence of overweight/obesity was higher in women. All metabolic risk factors were higher among people aged above 45 years.ConclusionsA signficant proportion of Ethiopian adults have at least one metabolic risk factor for NCDs. Despite heterogeneity of studies limiting the certainty of evidence, the result suggests the need for coordinated effort among policymakers, healthcare providers, non-governmental stakeholders and the community to implement appropriate preventive measures to reduce these factors.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0253605
Author(s):  
Bihungum Bista ◽  
Meghnath Dhimal ◽  
Saroj Bhattarai ◽  
Tamanna Neupane ◽  
Yvonne Yiru Xu ◽  
...  

Background The World Health Organization (WHO) recommends ongoing surveillance of non-communicable diseases (NCDs) and their risk factors, using the WHO STEPwise approach to surveillance (STEPS). The aim of this study was to assess the distribution and determinants of NCD risk factors in Nepal, a low-income country, in which two-thirds (66%) of annual deaths are attributable to NCDs. Methods A nationally representative NCD risk factors STEPS survey (instrument version 3.2), was conducted between February and May 2019, among 6,475 eligible participants of age 15–69 years sampled from all 7 provinces through multistage sampling process. Data collection involved assessment of behavioral and biochemical risk factors. Complex survey analysis was completed in STATA 15, along with Poisson regression modelling to examine associations between covariates and risk factor prevalence. Results The most prevalent risk factor was consumption of less than five servings of fruit and vegetables a day (97%; 95% CI: 94.3–98.0). Out of total participants, 17% (95% CI: 15.1–19.1) were current smoker, 6.8% (95% CI: 5.3–8.2) were consuming ≥60g/month alcohol per month and 7.4% (95% CI:5.7–10.1) were having low level of physical activity. Approximately, 24.3% (95% CI: 21.6–27.2) were overweight or obese (BMI≥25kg/m2) while 24.5% (95% CI: 22.4–26.7) and 5.8% (95% CI: 4.3–7.3) had raised blood pressure (BP) and raised blood glucose respectively. Similarly, the prevalence of raised total cholesterol was 11% (95% CI: 9.6–12.6). Sex and education level of participants were statistically associated with smoking, harmful alcohol use and raised BP. Participants of age 30–44 years and 45–69 years were found to have increased risk of overweight, raised BP, raised blood sugar and raised blood cholesterol. Similarly, participants in richest wealth quintile had higher odds of insufficient physical inactivity, overweight and raised blood cholesterol. On average, each participant had 2 NCD related risk factors (2.04, 95% CI: 2.02–2.08). Conclusion A large portion of the Nepalese population are living with a variety of NCD risk factors. These surveillance data should be used to support and monitor province specific NCD prevention and control interventions throughout Nepal, supported by a multi-sectoral national coordination mechanism.


2016 ◽  
Vol 3 (1) ◽  
pp. 24
Author(s):  
Ranka Jaćimović

The world today is faced with a growing increase in chronic non-communicable diseases (CNB), which become the leading cause of death. In 2012, the CNB were responsible for 38 million (68%) of all the 56 million deaths. Of that number, more than 40% died were younger than 70 years, and more than 82% of deaths were in underdeveloped and developing countries.The main risk factors in the development of the CNB are hypertension, hyperlipidemia, hyperglycemia, obesity and smoking. Reducing risk factors and timely detection and treatment is the least expensive way to solve the non-communicable diseases. The depletion of CNB has guiding public policy to promote the prevention, early detection and treatment of these diseases. In order to evaluate how successful strategies to combat rate for the Republica Srpska we examined the prevalence of risk factors for CNB at 1,454 patients older than 18 years in a team of family medicine DZ Banja Luka.The results indicate that high blood pressure is present in 40% of patients, dyslipidemia in 60%, with a high presence of hyperglycemia 23.5%. Smoking as a risk factor is present in 41% of subjects. One in five respondents were obese (BMI> 30).Our results suggest that the measures in the Republica Srpska invest in the prevention and treatment of CNB are not successful and are similar to those in the least developed countries.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
G Grosso

Abstract Background modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention of chronic non-communicable diseases (NCD). Among various risk factors, poor nutrition quality has been identified as a leading determinant of NCD. Methods The Global Burden of Diseases (GBD) Study provided a comprehensive comparative risk assessment (CRA) of risk factor for NCD, quantifying the impact of behavioural, environmental and occupational, and metabolic risk-outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. Special focus on nutritional risk factors will be dedicated, discussing the proportion of disease-specific burden attributable to each dietary risk factor and the level of intake associated with the lowest risk of mortality. Results In 2017, over 30 million deaths were attributable to risk factors. When ranked, high systolic blood pressure was the leading risk factor, accounting for more than 10 million deaths, followed by, high fasting plasma glucose, and high body-mass index. A total of 11 million deaths were attributable to dietary risk factors. High intake of sodium, low intake of whole grains, and low intake of fruits were the leading dietary risk factors for deaths globally. However, important differences between regions and outcome (i.e., cardiovascular disease vs. cancer) have been registered. Besides the major aforementioned factors, underrated dietary risk factors, such as low calcium intake, have been found important contributors to cancer burden in certain developed countries. Interpretation The combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in NCD at the global level. These data provide a comprehensive picture of the potential impact of suboptimal diet on NCD mortality and morbidity, highlighting the need for improving diet across nations.


2020 ◽  
Author(s):  
Sphamandla Josias Nkambule ◽  
Indres Moodley ◽  
Desmond Kuupiel ◽  
Tivani P. Mashamba-Thomson

Abstract BackgroundIn previous studies, food insecurity has been hypothesised to promote the prevalence of metabolic risk factors on the causal pathway to diet-sensitive non-communicable diseases (NCDs). This prevalence has been shown to differ between gender and populations. However, evidence of this association in resources-limited settings with high levels of food insecurity such as sub-Saharan African countries remains elusive.PurposeWe aimed to identify the association between food insecurity and key metabolic risk factors on the causal pathway to diet-sensitive NCDs in sub-Saharan African population.MethodsWe did a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Relevant studies published between January 2015 and October 2019 were searched in PubMed, Web of Science (SCiELO Citation Index), and five other databases followed by explicit and reproducible hand-searches of included studies which were peer-reviewed epidemiological studies conducted in sub-Saharan Africa, directly measured food insecurity, and compared food insecurity to a metabolic risk factor outcome. Two reviewers extracted all the necessary data from individual studies independently and employed the Mixed Methods Appraisal Tool (MMAT) – Version 2018 to evaluate the risk of bias. Prevalence estimates from individual studies were pooled using the random-effect model.ResultsThe initial searches yielded 11 803 articles, 22 were eligible for inclusion, presenting data from 26 609 food-insecure participants and 11 545 incident of metabolic risk factor cases. Most studies confirmed an adverse association between food insecurity and key metabolic risk factors for diet-sensitive NCDs. The Meta-analysis showed a significantly high pooled prevalence estimate of key metabolic risk factors at 41.8 per cent (95% CI: 33.2% to 50.8%, I2 = 99.5% p-value < 0.00). The most prevalent type of metabolic risk factors was dyslipidaemia 27.6 per cent (95% CI: 6.5% to 54.9%), hypertension 24.7 per cent (95% CI: 15.6% to 35.1%), and overweight 15.8 per cent (95% CI: 10.6% to 21.7%). Notably, the prevalence estimates of these metabolic risk factors were considerably more frequent in females than males.ConclusionThis study is the first to systematically review or meta-analyse the association between food insecurity and key metabolic risk factors for diet-sensitive non-communicable diseases (NCDs) in sub-Saharan African countries, in order to generate an integrated, evidence-based, comprehensive summary of how key metabolic risk factors are patterned by food insecurity. Further high-quality longitudinal data and mediation analysis are warranted to understand the basis of this findings to support targeted prevention and control strategies for those confronted with food insecurity.PROSPERO registration number: PROSPERO 2019 CRD42019136638


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Yuliaji Siswanto ◽  
Ita Puji Lestari

Non-communicable diseases (NCDs) including the most causes of death in the world including Indonesia.  Adolescence is one of the periods that determine the pattern of formation of health status in adulthood. Risk behaviors generally begin in the teenage period. Risk factors for unhealthy lifestyles in adolescents are caused by many factors, one of which is knowledge. Knowledge or cognitive is a domain that is very influential on a person's actions or behavior. The objective of the study was to assesknowledge about NCDs and behavioural risk factors in adolescents. This research uses descriptive method with cross sectional approach and data collection is done by using a questionnaire. The sample in this study was taken purposively from SMAN 2 Ungaran, SMAN 1 Bergas, and SMA Muhammadiyah Sumowono as many as 146 students. The data obtained were then analyzed using descriptive analysis. The results showed that the most percentage were respondents who had good knowledge about non-communicable diseases that was equal to 46.3%. Nevertheless there are still many respondents who have a fairly good knowledge of 41.8% and as many as 11.0% of respondents still have poor knowledge. Therefore, efforts are needed to increase the knowledge of high school adolescents about non-communicable diseases from schools through collaboration with relevant parties.


Author(s):  
Jacqueline Pitchforth ◽  
Dougal Hargreaves

Four non-communicable diseases (NCDs): cardiovascular disease, cancer, diabetes, and chronic respiratory conditions, are responsible for 63% of deaths worldwide. Most of these deaths (86%) occur in low and middle-income countries, where the highest proportion of adolescents live. Four shared behavioural risk factors for NCDs (tobacco use, unhealthy diet, physical inactivity, and harmful use of alcohol) are usually acquired during adolescence and persist throughout life. For example, globally 100,000 young people start smoking each day and over 90% of adults who smoke started during childhood or adolescence. This chapter will explore each of these risk factors, the impact on adolescent health and what steps are being taken to address these problems, as well as the contribution of chronic disease to the NCDs.


A key outcome in medical education is the training of doctors to acquire the knowledge and understanding of the basic science that underpins clinical practice. The graduate will be able to apply to medical practice biomedical scientific principles, method and knowledge relating to: anatomy, biochemistry, cell biology, genetics, immunology, microbiology, molecular biology, nutrition, pathology, pharmacology and physiology .’ (Tomorrow’s Doctors 2009, GMC, UK). In this, the last of the themed chapters of questions that map to the Oxford Handbook of Medical Sciences, we will test knowledge of infectious diseases and the host immune responses that counteract them. Despite the shift of the world health problem to non-communicable diseases in recent times (Global status report on non-communicable diseases 2010, World Health Organization), infectious diseases remain a major health problem in many parts of the world. Even in developed countries, epidemics and outbreaks of infections are not infrequent events, pandemics sporadically crop up at the least expected times. In addition, microorganisms constantly evolve to escape the host immune response and to develop resistance to treatments that have been developed. Therefore, we have no choice but to keep up our knowledge and to develop new treatments.


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