scholarly journals Formulation and antianaemic evaluation of the tablets containing Telfairia occidentalis aqueous leaf extract

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Aisha Daburi ◽  
Christianah Yetunde Isimi ◽  
Olubunmi Jumoke Olayemi
2019 ◽  
Vol 2 (2) ◽  
pp. 14-29
Author(s):  
B.C. Eze ◽  
D.N. Ezejindu ◽  
E.C. Ogbodo ◽  
I.P. Ezeugwunne ◽  
A.K. Amah ◽  
...  

Aim: Telfairia occidentalis has been reported to possess numerous health benefits. This study assessed the histomorphological effect of aqueous leaf extract of Tefairia occidentalis on the liver architecture of wistar rats. Methodology: Sixteen adult female rats weighing between 140-240g were divided into four groups (I-IV) comprising of four (4) rats each. Group I, the control, was given normal rat feed with water, while group II, III, and IV were administered with 150mg/kg, 300mg/kg and 600mg/kg body weight of aqueous leaf extract of Telfairia occidentalis orally respectively via intubation method for 28 days. Thereafter, the experimental animals were sacrificed and their respective liver harvested for histomorphological examination using haematoxylin and eosin (H and E) standard laboratory method. Results: Results showed that there was a significant decrease in the relative weight of the liver in groups II-IV when compared to group I respectively (p<0.05). Photomicrographic section of the liver showed normal hepatic tissue architecture with central vain (CV), portal triad (PT) and hepatocyte (H) in the control animals while photomicrograph section of the liver administered with 150mg/kg aqueous extract of Telfairia occidentalis showed hepatic tissue with focal aggregate inflammatory cell (FAIC) and normal tissue architecture with portal triad (PT) but photomicrograph of liver administered with 300mg/kg and 600mg/kg aqueous extract of Telfairia occidentalis showed alterations. Conclusion: This study revealed that the aqueous leaf extracts of Telfairia occidentalis may possess hepatoprotective effects although it may enhance some physiological changes such as mild hemolysis, infiltration of some inflammatory cells and intra-hepatic hemorrhage detected in this study. Key Words: liver, histomorphology, Telfairia occidentalis, weight, hepatoprotective effect.


2015 ◽  
Vol 14 (2) ◽  
pp. 88 ◽  
Author(s):  
SakpaLucky Christopher ◽  
Onovughakpo-SakpaOriseseyigbemi Ejuoghanran ◽  
OkhimamheAkhalumhe Festus

2020 ◽  
Vol 7 (1) ◽  
pp. 39-42
Author(s):  
Emmanuel Chukwuemeka Ogbodo ◽  
Damian Nnabuihe Ezejindu ◽  
Ifeoma Priscilla Ezeugwunne ◽  
Rosemary Adamma Analike ◽  
Blessing Chiamaka Eze

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381 ◽  
Author(s):  
S Sarshar ◽  
MR Asadi Karam ◽  
M Habibi ◽  
S Bouzari ◽  
X Qin ◽  
...  

2019 ◽  
Vol 35 (1) ◽  
pp. 145-153
Author(s):  
O. Uyi, ◽  
I.G. Amolo ◽  
A.D. Adetimehin

Several studies have demonstrated the biological efficacy of leaf, stem and root powders or extracts of Chromolaena odorata (L.) King and Robinson against insect pests but those that are focused on the biological efficacy of aqueous leaf extracts against Macrotermes species are scanty. Current management of termites with synthetic insecticides is being discouraged due to human and environmental hazards. Therefore, the insecticidal effectiveness of aqueous leaf extract C. odorata against Macrotermes species was investigated. Five concentrations (0, 2.5, 5.0, 7.5 and 10.0% (w/v)) of the aqueous extract of C. odorata plant were evaluated for repellency and toxicity on the worker caste of Macrotermes species following standard procedures. The filter paper impregnation technique was used for the bioassay. Percentage repellency was monitored for 30 minutes and mortality recorded at 12, 24 and 36 hours post exposure. The leaf extract of C. odorata significantly repelled 95% of Macrotermes species at the highest concentration of 10% (w/v) after 30 minutes post treatment exposure. Mortality of Macrotermes species was independent of treatment concentration, but dependent on duration of exposure. All treatment concentrations of aqueous leaf extract of C. odorata caused significant mortality against Macrotermes species ranging between 94% and 98% compared to the control; indicating very great potential for adoption and use in the management of Macrotermes species.


Author(s):  
M. Linga Rao ◽  
Bhumi G ◽  
Savithramma N

Silver nanoparticles (SNPs) exhibit tremendous applications in medicine as antimicrobial agent.  The use of different parts of plants for the synthesis of nanoparticles is considered as a green technology as it does not involve any harmful chemicals.  In the present study, we report a rapid biosynthesis of silver nanoparticles from aqueous leaf extract of medicinal plant Allamanda cathartica.  The active phytochemicals present in the plant were responsible for the quick reduction of silver ion to metallic silver nanoparticles. The reduced silver nanoparticles were characterized by using UV-Vis spectrophotometry, Scanning Electron Microscope (SEM), Energy Dispersive Analysis of X-ray (EDAX) and Atomic Force Microscopy (AFM).  The spherical shaped silver nanoparticles were observed and it was found to 19-40 nm range of size.  These phytosynthesized SNPs were tested for their antimicrobial activity and it analyzed by measuring the inhibitory zone. A. cathartica aqueous leaf extract of SNPs showed highest toxicity to Pseudomonas followed by Klebsiella, Bacillus and E. coli and lowest toxicity towards Proteus. In fungal species, highest inhibition zone was noted against Rhizopus followed by Curvularia, Aspergillus flavus and Aspergillus niger and minimum inhibition zone was observed against Fusarium species.  These results suggest a promising potential of Indian plant-based green chemistry for production of SNPs for biomedical and nanotechnology applications.


2021 ◽  
pp. 111335
Author(s):  
Mathiyazhagan Narayanan ◽  
Paramasivam Vigneshwari ◽  
Devarajan Natarajan ◽  
Sabariswaran Kandasamy ◽  
Mishal Alsehli ◽  
...  

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