scholarly journals Singapore's biomedical science sector development strategy: Is it sustainable?

10.5912/jcb93 ◽  
2004 ◽  
Vol 10 (4) ◽  
Author(s):  
Lisa P L Lim ◽  
Michael J Gregory
Keyword(s):  
Development Strategy ◽  
Early Stage ◽  
Biomedical Science ◽  
Small Country ◽  
Development Models ◽  
The Past ◽  
Science Area ◽  
The Uk ◽  
Economic Size

This paper outlines the strategic efforts undertaken by Singapore to establish its national capability in the biomedical science sector, reviews the commercial base as a result of these efforts and compares Singapore's approach with the UK and US development models, discusses the challenges that Singapore faces and raises some questions on the long-term sustainability of the sector.Although Singapore is a small country in terms of geographical size, its economic size is significant, with gross domestic product (GDP) and GDP per capita of US$112bn and US$25,200 respectively in 2002. For the past 40 years, the country has achieved an average annual GDP growth of 8.4 per cent by focusing on manufacturing and productivity improvements. Biotechnology has been earmarked as the next wave of technology that will sustain the country's economic growth. For almost two decades, Singapore has focused its efforts on building capabilities in the biomedical science area to exploit biotechnology and traditional chemistry-based technologies in drug discovery, development and production. The main principle of Singapore's strategy is to locate a sector targeted for growth and then to focus its efforts on building the key pillars to support the sector; identified in this case to be research, early stage funding and specialised infrastructure.

The Britannia Field, Blocks 15/29, 15/30, 16/26 and 16/27, UK North Sea

2020 ◽  
Vol 52 (1) ◽  
pp. 664-678 ◽  
Author(s):  
M. Camm ◽  
L. E. Armstrong ◽  
A. Patel
Keyword(s):  
Continental Shelf ◽  
Development Strategy ◽  
North Sea ◽  
Lower Cretaceous ◽  
Near Field ◽  
Field Development ◽  
Infill Drilling ◽  
To Come ◽  
The Uk

AbstractThe Lower Cretaceous Britannia Field development is one of the largest and most significant undertaken on the UK Continental Shelf. Production started in 1998 via 17 pre-drilled development wells and was followed by a decade of intensive drilling, whereby a further 40 wells were added. In 2000 Britannia's plateau production of 800 MMscfgd supplied 8% of the UK's domestic gas requirements.As the field has matured, so too has its development strategy. Initial near-field development drilling targeting optimal reservoir thickness was followed by extended reach wells into the stratigraphic pinchout region. In 2014 a further strategy shift was made, moving from infill drilling to a long-term compression project to maximize existing production. During its 20-year history the Britannia Platform has undergone numerous changes. In addition to compression, production from five satellite fields has been routed through the facility: Caledonia (2003), Callanish and Brodgar (2008), Enochdhu (2015) and Alder (2016). A new field, Finlaggan, is due to be brought through Britannia's facilities in 2020, helping to maximize value from the asset for years to come.As Britannia marks 20 years of production it has produced c. 600 MMboe – surpassing the original ultimate recoverable estimate of c. 570 MMboe – and is still going strong today.

Worker and Community Ownership as an Economic Development Strategy: Innovative Rebirth or Tired Retread of a Failed Idea?

2020 ◽  
Vol 34 (4) ◽  
pp. 325-342
Author(s):  
Jason S. Spicer
Keyword(s):  
Economic Development ◽  
Development Strategy ◽  
Early Stage ◽  
Historical Analysis ◽  
Popular Education ◽  
Community Capacity ◽  
Community Ownership ◽  
The Past ◽  
Education Community ◽  
State And Local

A generation ago, American state and local experiments with worker and community ownership appeared unsuccessful. Does their current revival offer anything new to the field of economic development or is this merely a tired retread of a failed idea? Using historical analysis, case studies, and interview data from three U.S. regions, the author analyzes the current range of initiatives that seek to remove impediments, stimulate development, and provide direct technical and financial support to worker and community-owned enterprises. The author also identifies how these efforts differ from those in the past, with respect to scope, scale, and success orientation. Collectively, these differences suggest a focus on engaging with, rather than escaping from, market-based economic development. Key challenges are also identified: popular education, community capacity, competitive pressure, early-stage financing, and managing political content. While too early to assess outcomes, these differences suggest the possibility of more substantial results than in the past.

No Margin for Error: Fifteen Years in the Working Lives of Lone Mothers and their Children

2018 ◽  
Vol 49 (1) ◽  
pp. 1-17 ◽  
Author(s):  
JANE MILLAR ◽  
TESS RIDGE
Keyword(s):  
Low Income ◽  
Security Policy ◽  
Qualitative Research Study ◽  
The Past ◽  
Lone Mothers ◽  
Working Lives ◽  
The Uk ◽  
Social Security Policy ◽  
Over Time

AbstractOver the past two decades, the emphasis on paid work has become one of the defining features of social security policy in the UK. Lone mothers and their families have been one of the key groups affected. In this article we focus on the working and family lives of lone mothers and their children over time, drawing on material from a long-term qualitative research study, and setting this in the context of policy developments. We explore the long-term consequences of trying to sustain work, and manage low-income family life as children grow up and needs change over time. This highlights some of the tensions and limitations in family support and relationships when resources are limited. We reflect on the links between insecurity, legacies and the state.

scholarly journals Prevalence of long-term oral glucocorticoid prescriptions in the UK over the past 20 years

Rheumatology ◽  
2011 ◽  
Vol 50 (11) ◽  
pp. 1982-1990 ◽  
Author(s):  
L. Fardet ◽  
I. Petersen ◽  
I. Nazareth
Keyword(s):  
Oral Glucocorticoid ◽  
The Past ◽  
The Uk

Trends underlying early-stage drug discovery and development collaborations from October 2002 to September 2004

2005 ◽  
Vol 11 (4) ◽  
Author(s):  
Mark J Belsey ◽  
Alex K Pavlou
Keyword(s):  
Drug Discovery ◽  
Early Stage ◽  
Target Identification ◽  
New Wave ◽  
Fully Integrated ◽  
Drug Discovery And Development ◽  
The Past ◽  
Initial Stage ◽  
Increasing Demand

As part of Datamonitor's alliance and licensing strategic analysis, the authors have completed a two year survey of the trends underlying early-stage drug discovery and development collaborations between October 2002 and September 2004, which included 524 early-stage deals. Deal analysis shows that the leading pharma and biotech companies (fully integrated players) are the principal collaboration seekers, and that target and product innovation is driving the new wave of 21st century deals. These deals cover all phases of early-stage drug development, with lead product/target identification/validation accounting for the greatest proportion of collaborations. This represents a shift away from initial-stage collaborations, which are primarily focused on technologies such as genomics, as a result of the lack of tangible results that such technologies have delivered in the past. Following the continuously increasing demand for late-stage high-value products, the aim of the money and time invested in these early-stage collaborations is to reverse the pipeline productivity crisis currently affecting the industry's leaders over the mid to long term.

The success of the Rapid Diagnostic Clinic (RDC) detecting new cancers in patients with non-localizing symptoms.

2020 ◽  
Vol 38 (29_suppl) ◽  
pp. 303-303
Author(s):  
Jan Sindhar ◽  
Sabine Martin ◽  
Loay Rahman ◽  
Sifan Zheng ◽  
Yaseen Mukadam ◽  
...  
Keyword(s):  
Primary Care ◽  
Cancer Diagnosis ◽  
Primary Care Physicians ◽  
Early Stage ◽  
Recovery Phase ◽  
Referral Criteria ◽  
Anti Cancer ◽  
Set Up ◽  
The Uk

303 Background: Rapid Diagnostic Clinics (RDC) are being set up across the UK allow primary care physicians to refer patients with symptoms concerning for cancer that do not fulfil tumour-specific two week wait urgent referral criteria. Guy’s RDC was established to address the high cancer related mortality in our network. There is little data assessing the effectiveness of RDC models is available in a British population. Methods: We evaluated all patients referred to Guy’s RDC pilot scheme between December 2016-June 2019 (n=1,341) to assess the rate and type of cancer diagnosed and clinical outcomes. Results: Of 1341 patients, 96 cancers were diagnoses (7.2%). Most common were lung (16%), haematological (13%) and colorectal (12%). A third were at early stage (I-II) and 40% received radical treatment. Median time to cancer diagnosis 28 days (IQR 15-47) and treatment 56 days (IQR 32-84). 75% of patients were suitable for anti-cancer treatment: surgery (26%), systemic (24%) and radiotherapy (14%). We plan to present updated data on > 2000 patients referred until June 2020. Overall 6% of patients were diagnosed with pre-malignant conditions. Conclusions: RDCs provide a streamlined pathway for complex vague symptoms patients which are challenging for primary care. The 7% rate of cancer diagnosis exceeds many tumour specific urgent pathways which supports the need for rapid tailored diagnostics. The detection of pre-malignant conditions in 6% allows surveillance and intervention to potentially improve long-term outcomes. RDCs are likely to be pivotal in the cancer recovery phase of the COVID-19 pandemic.

Average Wage Prediction Based on Logistic Model

2013 ◽  
Vol 483 ◽  
pp. 615-618
Author(s):  
Zheng Xi Wei ◽  
Jin Ming Liang ◽  
Pan Zhao
Keyword(s):  
Development Strategy ◽  
Logistic Model ◽  
Prediction Method ◽  
Reference Value ◽  
Provincial Government ◽  
Average Wage ◽  
Growth Trend ◽  
The Past ◽  
National Economic

In this paper, data mining technology is applied to analyze the average wage of staff and workers in urban of Sichuan Province, China. The salary data in the past 22-year is sourced from Sichuan Provincial Government to publish during 1991 to 2012. Combined with Chinese national economic-development strategy, the Logistic Prediction Model is established by our much research. The future average wage from 2013 to 2020 year of staff and workers in urban is predicted and its growth trend in the long term is pointed out. The macro analysis to predicting data from Logistic model proves the prediction method and its conclusion is of certain reference value.

scholarly journals Workfare – a Blast from the Past? Contemporary Work Conditionality for the Unemployed in Historical Perspective

2014 ◽  
Vol 14 (3) ◽  
pp. 329-339 ◽  
Author(s):  
Del Roy Fletcher
Keyword(s):  
Historical Analysis ◽  
Historical Review ◽  
Work Activity ◽  
Economic Theories ◽  
The Past ◽  
British Labour ◽  
Contemporary Work ◽  
The Uk ◽  
The Unemployed

During 2011, the UK Government introduced the Mandatory Work Activity scheme, which requires JSA claimants to work in order to continue receiving benefit. Workfare has been viewed as a radical departure in the evolution of British labour market policy. However, an historical review of workfare in inter-war Britain reveals that the most recent proposals merely resuscitate a heritage of compelling the long-term unemployed to work for their benefit. Both then and now workfare has flourished in times of economic crisis, and particularly where Governments have pursued economic theories which exalt the market. Historical analysis reveals important continuities and changes in the nature of contemporary workfare.

scholarly journals Optimising social mixing strategies achieving COVID-19 herd immunity while minimising mortality in six European countries

2020 ◽  
Author(s):  
Romain Ragonnet ◽  
Guillaume Briffoteaux ◽  
Bridget M. Williams ◽  
Julian Savulescu ◽  
Matthew Segal ◽  
...  
Keyword(s):  
Time Horizon ◽  
Herd Immunity ◽  
Mitigation Strategies ◽  
Social Contacts ◽  
The Past ◽  
Social Mixing ◽  
The Uk ◽  
The Impact ◽  
Related Mortality

AbstractStrategies are needed to minimise the impact of COVID-19 in the medium-to-long term, until safe and effective vaccines can be used. Using a mathematical model in a formal optimisation framework, we identified contact mitigation strategies that minimised COVID-19-related mortality over a time-horizon of 15 months while achieving herd immunity in six or 12 months, in Belgium, France, Italy, Spain, Sweden, and the UK. We show that manipulation of social contacts by age can reduce the impact of COVID-19 considerably in the presence of intense transmission. If immunity was persistent, the optimised scenarios would result in herd immunity while causing a number of deaths considerably lower than that observed during the March-April European wave in Belgium, France, Spain and Sweden, whereas the numbers of deaths required to achieve herd immunity would be comparable to somewhat larger that the past epidemics in Italy and the UK. Our results also suggest that countries’ herd immunity thresholds may be considerably lower than first estimated for SARS-CoV-2. If post-infection immunity was short-lived, ongoing contact mitigation would be required to prevent major epidemic resurgence.

scholarly journals Youth transitions, unemployment and underemployment

2011 ◽  
Vol 47 (4) ◽  
pp. 427-444 ◽  
Author(s):  
Robert MacDonald
Keyword(s):  
Social Change ◽  
Youth Policy ◽  
Youth Studies ◽  
The Past ◽  
Economic Marginality ◽  
Youth Research ◽  
Theoretical Significance ◽  
The Uk ◽  
Youth Transitions

What is youth studies for? One answer to this question points to the valuable, possibly unique, position youth research has as a window on processes of social change and of social continuity. Based on the author’s long-term engagement in youth research, from the early 1980s to now, this article reflects on how youth transitions to the labour market – and the way that they are thought about in youth studies and youth policy – have changed and stayed the same over the past 30 years. While the main empirical focus is on the UK, the article notes the wider relevance of many of the trends that are discussed. As well as looking backward, the article considers possibilities and challenges for the future; for youth, for youth research and for youth policy. In terms of young adults’ lives, the spreading shadow of unemployment, economic marginality and precariousness is described. In terms of research, it argues that, in order to achieve greater theoretical significance and impact for youth studies – and to better understand processes of social change and continuity – further strides need to be taken to overcome the enduring divide between youth cultural and youth transitions studies. Finally, on the basis of these reflections from youth studies, the article raises important questions for current and coming social and economic policy. Here the local – and global – significance of underemployment and the ‘myth of the skills economy’ are discussed.

Sign in / Sign up

Export Citation Format

Share Document