scholarly journals Antispermatogenic effects of aqueous ethanolic extract of Hymenocardia acida stem bark in Wistar rats

2010 ◽  
Vol 4 (23) ◽  
pp. 2495-2502 ◽  
Author(s):  
A H Abu ◽  
C N Uchendu
Keyword(s):  
Wistar Rats ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Aqueous Ethanolic Extract

Pharmacognostic Evaluation of Bambusa vulgaris Var. vulgaris Leaf and its Toxicity Studies in Male Wistar Rats

2015 ◽  
Vol 19 ◽  
pp. 106-114
Author(s):  
GO Alade ◽  
KK Ajibesin ◽  
OR Omobuwajo
Keyword(s):  
Wistar Rats ◽  
Histopathological Examination ◽  
Ethanolic Extract ◽  
Calcium Oxalate Crystals ◽  
Blood Cell Count ◽  
Bambusa Vulgaris ◽  
Anomocytic Stomata ◽  
Male Wistar Rats ◽  
Aqueous Ethanolic Extract ◽  
Low Toxicity

The study evaluated the pharmacognostic characters and toxicity of the aqueous ethanolic extract of Bambusa vulgaris leaf in male wistar rats. The microscopy of the leaf revealed diagnostic characters such as anomocytic stomata, sinuous epidermal cells, numerous prisms of calcium oxalate crystals and covering trichomes. Histopathological examination revealed no significant adverse effects on the lungs, kidneys and the spleens after fourteen days oral administration of the extract at 250 and 500 mg/kg doses. Haematological evaluation however revealed a significant 31% reduction (p<0.05) in packed cell volume and a significant 31% increase (p<0.05) in white blood cell count at 500 mg/kg. The results suggest that administration of B. vulgaris extract may possess low toxicity when used.Keywords: Bambusa vulgaris, Toxicity, Microscopy, Standardization, Histology

scholarly journals Toxicity profile of ethanolic extract of Azadirachta indica stem bark in male Wistar rats

2012 ◽  
Vol 2 (10) ◽  
pp. 811-817 ◽  
Author(s):  
Anofi Omotayo Tom Ashafa ◽  
Latifat Olubukola Orekoya ◽  
Musa Toyin Yakubu
Keyword(s):  
Azadirachta Indica ◽  
Wistar Rats ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Toxicity Profile ◽  
Male Wistar Rats

scholarly journals THE ROLE OF ETHANOLIC EXTRACT OF SYZYGIUM CUMINI STEM BARK ON FEMALE REPRODUCTIVE SYSTEM IN WISTAR RATS

2020 ◽  
Vol 8 (4.2) ◽  
pp. 7835-7840
Author(s):  
Mergu Prasad ◽  
◽  
Satya Prasad Venugopal ◽  
Keyword(s):  
Body Weight ◽  
Reproductive System ◽  
Wistar Rats ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Treated Group ◽  
The Body ◽  
Syzygium Cumini ◽  
Female Reproductive System ◽  
Traditional Practitioners

Background: The medicinal plant's role is well established in folklore medicine in India. Among numerous health complications, infertility is a crucial condition that bothers modern society. The traditional practitioners are using various parts of plants to overcome infertility in women. One such plant is Syzygium cumini (stem bark), used by traditional practitioners for pro-fertility in females without the scientific literature endorsing the fact. Material and Methods: Wistar rats approximately six months age and weighing 190-210 g were used for the experimental study. The rats were treated with 500 mg/kg body weight of Syzygium cumini stem bark ethanol extract with a vehicle through oral administration. The ether anaesthesia was given on the day of sacrifice and noted the body weight. The ovaries were carefully dissected, cleaned, weighed and processed for histological studies. Results: The body and ovarian weights were slightly increased in the treated group but not statistically significant. The microscopic structure of the ovary showed a normal histo-architecture. The ovarian corpora lutea number increased and was statistically significant in the treated group when compared to control. Conclusions: So, from the present study, it can be concluded that the ethanolic extract of stem bark of Syzygium cumini brings about the pro-fertility effect on the female reproductive system in Wistar rats. KEY WORDS: Estrous cycle, Hormones, Reproductive system, Syzygium cumini.

scholarly journals Comparative effects of ethanol leaf and stem bark extracts of Irvingia gabonensis (BUSH MANGO) on sodium arsenite-induced lipid profile perturbtions in wistar rats

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Efosa Godwin Ewere ◽  
Ngozi Paulinus Okolie ◽  
Erhunmwunsee Dalton Avan ◽  
Patience Edet Umoh
Keyword(s):  
Lipid Profile ◽  
Wistar Rats ◽  
Sodium Arsenite ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Stem Bark ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Irvingia Gabonensis

Abstract Background Exposure to arsenic orchestrates a myriad of noxious health effects, including cancer. Different parts of Irvingia gabonensis are used as herbal remedies in traditional medicine. In this study, the comparative effects of the ethanol leaf (ELEIG) and stem bark extracts (ESEIG) of Irvingia gabonensis on sodium arsenite (SA)-induced lipid profile disturbances in Wistar rats were investigated. Methods Fifty five Wistar rats weighing between 100 g and 179 g were distributed into eleven groups (n=5). Group 1 (control) received feed and water ad libitum. Group 2 received SA at a dose of 4.1 mg/kg body weight (kgbw) for 14 days. Groups 3–11 were treated with the extracts with or without SA. Treatment was done by oral intubation for 14 days. Serum concentrations of total cholesterol (TC), triacylglycerol (TAG), high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c), total lipids (TL) and atherogenic index of plasma (AIP) were used to determine the lipid profile effects of the extracts. Results Exposure to SA caused significant (p ˂ 0.05) increases in all assayed parameters, relative to control. Post-treatment and simultaneous treatment with ELEIG and ESEIG mitigated the effects of SA. In addition, ELEIG alone at various doses produced results comparable with control values. However, ESEIG alone caused significant (p ˂ 0.05) increases in all assayed parameters, relative to control. Conclusion These results show that ELEIG and ESEIG ameliorate SA-induced lipid profile disturbances in Wistar rats. However, long-term administration of ESEIG alone may be discouraged.

Sign in / Sign up

Export Citation Format

Share Document