scholarly journals Biological and biochemical responses of infected Biomphalaria alexandrina snails with Schistosoma mansoni post exposure to the pesticides Basudin and Selecron and the phytoalkaloid Colchicine

2012 ◽  
Vol 4 (2) ◽  
pp. 24-32 ◽  
Author(s):  
M. Mohamed
Keyword(s):  
Schistosoma Mansoni ◽  
Biomphalaria Alexandrina ◽  
Post Exposure ◽  
Biochemical Responses

scholarly journals Molecular approach for detecting early prepatent Schistosoma mansoni infection in Biomphalaria alexandrina snail host

2014 ◽  
Vol 40 (3) ◽  
pp. 805-812 ◽  
Author(s):  
Adel Farghaly ◽  
Ayman A. Saleh ◽  
Soad Mahdy ◽  
Dalia Abd El-Khalik ◽  
Naglaa F. Abd El-Aal ◽  
...  
Keyword(s):  
Schistosoma Mansoni ◽  
Snail Host ◽  
Molecular Approach ◽  
Biomphalaria Alexandrina

scholarly journals Efficacy of Miltefosine and Artemether on infected Biomphalaria alexandrina snails with Schistosoma mansoni: immunological and histological studies

2020 ◽  
Vol 57 (4) ◽  
pp. 335-343
Author(s):  
H. H. Abdel-Azeem ◽  
G. Y. Osman ◽  
M. F. El Garhy ◽  
K. S. Al Benasy
Keyword(s):  
Electron Microscopy ◽  
Schistosoma Mansoni ◽  
Light And Electron Microscopy ◽  
Post Treatment ◽  
Sublethal Dose ◽  
Biomphalaria Alexandrina ◽  
Histological Studies ◽  
Morphological Abnormalities ◽  
Medical Importance

SummaryBiomphalaria alexandrina snails have received much attention due to their great medical importance as vectors for transmitting Schistosoma mansoni infection to humans. The main objective of the present work was to assess the efficacy of miltefosin a synthetic molluscicidal drug and artemether a natural molluscicidal drug. The correlation between immunological and histological observations from light and electron microscopy of the hemocytes of B. alexandrina post treatment with both drugs was also evaluated. LC50 and LC90 values were represented by 13.80 ppm and 24.40 ppm for miltefosine and 16.88 ppm and 27.97 ppm for artemether, respectively. The results showed that the treatment of S. mansoni-infected snails and normal snails with sublethal dose of miltefosine (LC25=8.20 ppm) and artemether (LC25=11.04 ppm) induced morphological abnormalities and a significant reduction in hemocytes count.

scholarly journals Spirostanol Saponins from Asparagus sprengeri and Their Molluscicidal Activity

2007 ◽  
Vol 2 (7) ◽  
pp. 1934578X0700200 ◽  
Author(s):  
Mona A. Mohamed
Keyword(s):  
Schistosoma Mansoni ◽  
Intermediate Host ◽  
Spectroscopic Data ◽  
Dry Powder ◽  
Biomphalaria Alexandrina ◽  
Butanol Extract ◽  
Spirostanol Saponins ◽  
Molluscicidal Activity ◽  
C Nmr

Two new spirostane saponins namely (25 R)-6α-[(β-D-glucopyranosyl)oxy]-5α-spirostan-3β-yl β-D-galactopyranoside (1) and (25 R)-6α-[(β-D-glucopyranosyl)oxy]-27-hydroxy-5α-spirostan-3β-yl β-D-glucopyranoside (2), together with three known metabolites (25 S)-5β-spirostan-3-β-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (3), (25 R)-5α-spirostan-3-β-yl O-β-D-galactopyranosyl-(1→2)- O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside (4) and (25 R)-5α-spirostan-3-β-yl O-β-D-glucopyranosyl-(1→3)- O-[β-D-xylopyranosyl-(1→2)]- O-β-D-glucopyranosyl-(1→4)-β-D-glactopyranoside (5) were identified from the leaves of Asparagus sprengeri Regel (Asparagaceae). Determination of the structures was based on chemical and spectroscopic data (HRESI-MS/MSn, 1H, DEPT 13C NMR, 1H-1H COSY, HSQC and HMBC). The dry powder, the 1-butanol extract of the leaves, and the isolated compounds (3–5) exhibited molluscicidal properties against Biomphalaria alexandrina snails (the intermediate host of Schistosoma mansoni) [LC90 = 150, 40, 7, 10 and 13 ppm, respectively], while compounds 1 and 2 were molluscicidally inactive.

Heavy metal concentrations in the freshwater snail Biomphalaria alexandrina uninfected or infected with cercariae of Schistosoma mansoni and/or Echinostoma liei in Egypt: the potential use of this snail as a bioindicator of pollution

2013 ◽  
Vol 88 (4) ◽  
pp. 411-416 ◽  
Author(s):  
O.M.S. Mostafa ◽  
A.-T.H. Mossa ◽  
H.M.A. El Einin
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Schistosoma Mansoni ◽  
Total Concentration ◽  
Parasitic Infection ◽  
Absorption Spectrometry ◽  
Freshwater Snail ◽  
Biomphalaria Alexandrina ◽  
Flame Atomic Absorption ◽  
The Status

AbstractIn spite of using aquatic snails as bioindicators for water pollution, little attention has been paid to the effect of parasitism upon the concentration of heavy metals (Al, Cd, Cu, Fe, Mn, Pb and Zn) in these organisms. The present study therefore aimed to compare the concentrations of heavy metals in trematode-infected Biomphalaria alexandrina collected from Kafer Alsheikh and Menofia provinces, Egypt, with uninfected snails from the same sites, in order to assess the effect of parasitism on the use of these snails as bioindicators. The concentrations of heavy metals in the soft parts and shells of snails were measured by flame atomic absorption spectrometry. The results showed that the heavy metal profile in snails infected with Echinostoma liei was very different from that in snails infected with Schistosoma mansoni. The total concentration of heavy metals in E. liei-infected snails collected from Kafer Alsheikh or Menofia province was greater than in uninfected snails. In contrast, the total concentration of heavy metals in S. mansoni-infected snails was reduced compared with uninfected snails. In conclusion, the status of snails with respect to parasitic infection must be taken into consideration when these snails are used as bioindicators.

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