scholarly journals Effect of diabetan on blood glucose, glycosylated hemoglobin, lipid profile, liver and kidney function tests of diabetic patients: A clinical, double blind, randomized trial

2013 ◽  
Vol 7 (2) ◽  
pp. 50-53 ◽  
Author(s):  
Behradmanesh Mohammad-Saeed
Keyword(s):  
Blood Glucose ◽  
Randomized Trial ◽  
Lipid Profile ◽  
Kidney Function ◽  
Glycosylated Hemoglobin ◽  
Diabetic Patients ◽  
Kidney Function Tests ◽  
Double Blind ◽  
Function Tests ◽  
Liver And Kidney

Measurements of Kidney Function Tests in Diabetic Patients Type 2

2019 ◽  
Vol 105 (6) ◽  
Author(s):  
Hassan AB ◽  
Merza FA ◽  
AL-Msaid HLF ◽  
Mushattat SJ
Keyword(s):  
Kidney Function ◽  
Diabetic Patients ◽  
Kidney Function Tests ◽  
Function Tests

scholarly journals In vivo and in vitro antidiabetic properties of alkaloids extract from Salvia chudaei

2021 ◽  
pp. 45-53
Author(s):  
Mohammed Tlili ◽  
Roukia Hammoudi ◽  
Mahfoud Hadj-Mahammed
Keyword(s):  
Blood Glucose ◽  
Lipid Profile ◽  
Kidney Function ◽  
Inhibitory Effect ◽  
Diabetic Rats ◽  
Albino Rats ◽  
Liver And Kidney ◽  
Mean Blood Glucose

The aim of this study was to evaluate, for the first time, the antidiabetic effect of the alkaloids extract of Salvia chudaei Batt. & Trab. (Lamiaceae) on alloxan-induced diabetic rats. The alkaloids extract was prepared, and the in vitro inhibitory effect of key digesting enzymes related to postprandial hyperglycemia were determined. After acute toxicity test, the Swiss albino rats were induced with alloxan to get experimental diabetes animals. The fasting mean blood glucose, lipid profile, different liver and kidney function biomarkers and antioxidant biomarkers levels, after treatment for 30 days, diabetic untreated and diabetic rats treated with alkaloids extract were estimated. The alkaloids displayed remarkable in inhibiting ?-glucosidase (IC50 = 248.25?2.61 ?g/ml) than ?-amylase (IC50 = 262.96?9.64 ?g/ml) activities. In vivo, the results proved that alkaloids extract at dose of 500 mg/kg bw decreased significantly the blood glucose, lipid profile levels and improved the liver and kidney function biomarkers and increased the activities of antioxidant enzymes (superoxide dismutase and gluthatione reductase). This study demonstrates, that alkaloids are effective in inhibiting hyperglycemia and oxidative stress caused by diabetes.

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