scholarly journals The antitumor effects of Araloside A extracted from the root bark of Aralia elata on human kidney cancer cell lines

2011 ◽  
Vol 5 (4) ◽  
pp. 462-467 ◽  
Author(s):  
Liu Yu
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Kidney Cancer ◽  
Human Kidney ◽  
Cancer Cell Lines ◽  
Root Bark ◽  
Antitumor Effects ◽  
Aralia Elata

scholarly journals Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro

2016 ◽  
Vol 11 (6) ◽  
pp. 4224-4234 ◽  
Author(s):  
GIOVANNI VANNI FRAJESE ◽  
MONICA BENVENUTO ◽  
MASSIMO FANTINI ◽  
ELENA AMBROSIN ◽  
PAMELA SACCHETTI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ascorbic Acid ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Antitumor Effects

scholarly journals Analyzing Cytotoxic and Apoptogenic Properties ofScutellaria litwinowiiRoot Extract on Cancer Cell Lines

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Zahra Tayarani-Najaran ◽  
Seyed Ahmad Emami ◽  
Javad Asili ◽  
Alireza Mirzaei ◽  
Seyed Hadi Mousavi
Keyword(s):  
Flow Cytometry ◽  
Cell Lines ◽  
Cancer Cell ◽  
Methylene Chloride ◽  
Apoptotic Cell ◽  
Malignant Cell ◽  
Cancer Cell Lines ◽  
Dependent Manner ◽  
Antitumor Effects ◽  
Mcf 7

TheScutellariaspecies (Lamiaceae) is used as a source of flavonoids to treat a variety of diseases in traditional medicine. In spite of many reports about the cytotoxic and antitumor effects of some species of this genus, anticancer researches on one of the Iranian speciesS. litwinowiihave not yet been conducted.The cytotoxic properties of total methanol extract ofS. litwinowiiand its fractions were investigated on different cancer cell lines including AGS, HeLa, MCF-7, PC12 and NIH 3T3. Meanwhile, the role of apoptosis in this toxicity was explored. The cells were cultured in DMEM medium and incubated with different concentrations of herb plant extracts. Cell viability was quantitated by MTT assay. Apoptotic cells were determined using propidium iodide staining of DNA fragmentation by flow cytometry (sub-G1 peak).Scutellaria litwinowiiinhibited the growth of malignant cells in a dose-dependent manner. Among solvent fractions ofS. litwinowii, the methylene chloride fraction was found to be more toxic compared to other fractions. The IC50values of this fraction against AGS, HeLa, MCF-7 and PC12 cell lines after 24 h were determined, 121.2 ± 3.1, 40.9 ± 2.5, 115.9 ± 3.5 and 64.5 ± 3.4μg/ml, respectively.Scutellaria litwinowiiinduced a sub-G1 peak in the flow cytometry histogram of treated cells compared to control cells indicating that apoptotic cell death is involved inS. litwinowiitoxicity.Scutellaria litwinowiiexerts cytotoxic and proapototic effects in a variety of malignant cell lines and could be considered as a potential chemotherapeutic agent in cancer treatment.

ANTITUMOR EFFECTS OF SCUTELLARIAE RADIX AND ITS COMPONENTS BAICALEIN, BAICALIN AND WOGONIN ON BLADDER CANCER CELL LINES

1999 ◽  
pp. 115
Author(s):  
Shinichi Ikemoto ◽  
Kazunobu Sugimura ◽  
Tatsuya Nakatani ◽  
Keisuke Yamamoto ◽  
Taketoshi Kishimoto
Keyword(s):  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Antitumor Effects ◽  
Scutellariae Radix

scholarly journals Antitumor Effects of Eribulin Mesylate in Gemcitabine-resistant Pancreatic Cancer Cell Lines

2016 ◽  
Vol 36 (11) ◽  
pp. 6077-6082 ◽  
Author(s):  
YUKA TAKEZAKI ◽  
TSUTOMU NAMIKAWA ◽  
TSUYOSHI KOYAMA ◽  
ERI MUNEKAGE ◽  
MASAYA MUNEKAGE ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Pancreatic Cancer Cell ◽  
Cancer Cell Lines ◽  
Antitumor Effects ◽  
Eribulin Mesylate

Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines

Urology ◽  
2000 ◽  
Vol 55 (6) ◽  
pp. 951-955 ◽  
Author(s):  
Shinichi Ikemoto ◽  
Kazunobu Sugimura ◽  
Naomasa Yoshida ◽  
Ryouji Yasumoto ◽  
Seiji Wada ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Bladder Cancer Cell ◽  
Antitumor Effects ◽  
Scutellariae Radix

Antiproliferative Activity of Protopine Extract from Fumaria agraria Against Human Lung Cancer Cell Lines

2021 ◽  
Author(s):  
K. Bougoffa-Sadaoui ◽  
F. Maiza-Benabdesselam ◽  
H. Ouadid-Ahidouch
Keyword(s):  
Lung Cancer ◽  
Cell Line ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Lung ◽  
Cancer Cell Lines ◽  
Human Lung Cancer ◽  
Lung Cancer Cell ◽  
Antitumor Effects ◽  
Fumaria Agraria

Little information is reported on the antitumor effects of isoquinoline alkaloids, particularly protopine, a major component of Fumaria agraria, on lung cancer. The purpose of our study is to determine the cytotoxic effect of protopine from an extraction by fractionation of the aerial part of Fumaria agraria on two lung cancer cell lines, NCI-H23 and NCI-H460. The basic fraction containing protopine (60.7%) has cytotoxicity to the two lung cancer cell lines studied here. The cell line NCI-H460 is more sensitive after 72 h of treatment by protopine with an IC50 of 08.5 ± 0.09 μMthan the cell line NCI-H23 (IC50 = 14.8 ± 0.03 μM).

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