scholarly journals Production of novel antifungal compounds from actinomycetes isolated from waste dump soil in Western Uganda

2017 ◽  
Vol 11 (30) ◽  
pp. 1200-1210 ◽  
Author(s):  
Almustapha Aliero Adamu ◽  
Ntulume Ibrahim ◽  
Odda John ◽  
Angela Okech Matilda
Keyword(s):  
Antifungal Compounds ◽  
Waste Dump ◽  
Western Uganda

Antibacterial Activity of Actinomycetes Isolated from Waste Dump Soil from Western Uganda

2017 ◽  
Vol 21 (5) ◽  
pp. 1-14
Author(s):  
Adamu Aliero ◽  
Eilu Emmanue ◽  
Maniga Josephat ◽  
Sambo Aliyu ◽  
Matilda Okech ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Waste Dump ◽  
Western Uganda

The phytotoxicity of waste dump coal mines under effect of stone powder and vermihumate

2017 ◽  
Vol 9 (1) ◽  
pp. 138-143
Author(s):  
Y Shpak ◽  
◽  
V Baranov ◽  
I Zapisotska ◽  
O Terek ◽  
...  
Keyword(s):  
Coal Mines ◽  
Waste Dump

The Effect of Onchocerciasis Elimination on Onchocerciasis-Associated Epilepsy in a Hyper-Endemic Focus of Western Uganda

2019 ◽  
Author(s):  
Nolbert Gumisiriza ◽  
C. Kaiser ◽  
G. Asaba ◽  
H. Onen ◽  
F. Mubiru ◽  
...  
Keyword(s):  
Endemic Focus ◽  
Western Uganda

Alternative Host Models for Testing Anti-Protozoal or Antifungal Compounds and Fungal Infection

2018 ◽  
Vol 18 (4) ◽  
pp. 300-311
Author(s):  
Ana Claudia Torrecilhas ◽  
Patricia Xander ◽  
Karen Spadari Ferreira ◽  
Wagner Luiz Batista
Keyword(s):  
Fungal Infection ◽  
Neglected Tropical Diseases ◽  
Alternative Methods ◽  
Laboratory Animals ◽  
Antifungal Compounds ◽  
Alternative Host ◽  
Control And Prevention ◽  
New Compounds ◽  
Invertebrate Models ◽  
Alternative Drugs

The neglected tropical diseases (NTDs) are caused by several parasites, fungi, bacteria and viruses and affect more than one billion people in the world. The control and prevention against NTDs need implementation of alternative methods for testing new compounds against these diseases. For the implementation of alternative methods, it is necessary to apply the principles of replacement, reduction and refinement (the 3Rs) for the use of laboratory animals. Accordingly, the present review addressed a variety of alternative models to study the infections caused by protozoa and fungi. Overall, vertebrate and invertebrate models of fungal infection have been used to elucidate host-pathogen interactions. However, until now the insect model has not been used in protozoal studies as an alternative method, but there is interest in the scientific community to try new tools to screen alternative drugs to control and prevent protozoal infections.

scholarly journals Care and support for youth living with HIV/AIDS in secondary schools: perspectives of school stakeholders in western Uganda

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Emmanuel Kimera ◽  
Sofie Vindevogel ◽  
Didier Reynaert ◽  
Anne-Mie Engelen ◽  
Kintu Mugenyi Justice ◽  
...  
Keyword(s):  
Secondary Schools ◽  
Qualitative Inquiry ◽  
Resource Limited ◽  
Care And Support ◽  
Gradual Process ◽  
Youth Living With Hiv ◽  
Living With Hiv ◽  
Western Uganda ◽  
Hiv Aids ◽  
School Stakeholders

Abstract Background Although schools have been identified as significant settings in the response to the HIV/AIDS pandemic, limited research is available on how they can accommodate Youth Living with HIV/AIDS (YLWHA), especially in resource limited countries. In this study, we explored strategies by school stakeholders (school staff, parents/caretakers, and students) in western Uganda to care for and support YLWHA in their schools. Methods The article utilizes data collected between May and October, 2019 from a qualitative inquiry based on focus group discussions and interviews with 88 school stakeholders purposively selected from 3 secondary schools in western Uganda. Textual data was analyzed thematically involving both inductive and deductive coding. Results We identified 7 overarching interrelated themes in which participants reported strategies to care for and support YLWHA: counselling and guidance; social support networks and linkages; knowledge and skills; anti-stigma and anti-discrimination measures; disclosure of HIV status; treatment and management of HIV/AIDS; and affirmative actions for YLWHA. Stakeholders’ strategies often differed regarding what was considered appropriate, the approach and who to take lead in supporting YLWHA. Conclusions Despite the limited care and support strategies specific for YLWHA currently available in schools, our study points to optimism and high potential given stakeholders’ identified avenues for improvement. We posit that promoting HIV/AIDS-care and support in schools is a gradual process requiring each school to develop a strong knowledge base about HIV/AIDS and support needs of YLWHA, develop a coherent and school-wide approach, and collaborate extensively with external stakeholders who are significant in supporting YLWHA.

scholarly journals Diffusible Compounds Produced by Hanseniaspora osmophila and Gluconobacter cerinus Help to Control the Causal Agents of Gray Rot and Summer Bunch Rot of Table Grapes

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 664
Author(s):  
Matías Olivera ◽  
Ninoska Delgado ◽  
Fabiola Cádiz ◽  
Natalia Riquelme ◽  
Iván Montenegro ◽  
...  
Keyword(s):  
Mycelial Growth ◽  
Inhibitory Effect ◽  
Biocontrol Agents ◽  
Environmental Cost ◽  
Antifungal Compounds ◽  
Table Grapes ◽  
Dual Cultures ◽  
Bunch Rot ◽  
Direct Bioautography

Gray and summer bunch rot are important diseases of table grapes due to the high economic and environmental cost of their control with synthetic fungicides. The ability to produce antifungal compounds against the causal agents Botrytis, Aspergillus, Penicillium, and Rhizopus of two microorganisms isolated from table grapes and identified as Hanseniaspora osmophila and Gluconobacter cerinus was evaluated. In dual cultures, both biocontrol agents (together and separately) inhibited in vitro mycelial growth of these pathogens. To identify the compounds responsible for the inhibitory effect, extractions were carried out with organic solvents from biocontrol agents separately. Through dual cultures with pathogens and pure extracts, only the hexane extract from H. osmophila showed an inhibitory effect against Botrytis cinerea. To further identify these compounds, the direct bioautography technique was used. This technique made it possible to determine the band displaying antifungal activity at Rf = 0.05–0.2. The compounds present in this band were identified by GC-MS and compared to the NIST library. The most abundant compounds, not previously reported, corresponded to alkanes, ketones, alcohols, and terpenoids. H. osmophila and G. cerinus have the potential to control the causal agents of gray and summer bunch rot of table grapes.

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