scholarly journals Antimicrobial susceptibility pattern of Gram-negative bacilli isolated from a Teaching Hospital in Jeddah, Saudi Arabia

2015 ◽  
Vol 9 (41) ◽  
pp. 2145-2158 ◽  
Author(s):  
M Zaman Razina ◽  
M Aly Magda ◽  
R Helmi Noof
Keyword(s):  
Saudi Arabia ◽  
Teaching Hospital ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern

scholarly journals Evaluation of Antimicrobial Susceptibility Pattern of Pathogenic Bacteria Causing Urinary Tract Infection in A Teaching Hospital

2021 ◽  
Vol 10 (9) ◽  
pp. 456-463
Author(s):  
Pradha Velu Ramya Rengaraj ◽  
Hemalatha Gurumurthy Saleem Mohamed Ali
Keyword(s):  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Teaching Hospital ◽  
Antimicrobial Susceptibility ◽  
Pathogenic Bacteria ◽  
Susceptibility Testing ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern ◽  
Klebsiella Spp

Aims: To determine the prevalence of pathogenic bacteria causing urinary tract infections and their antibiotics susceptibility pattern from patients reporting in a tertiary care teaching hospital. Study design: Retrospective study. Place and duration of the study: Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, January 2017 to December 2019. Methodology: 7825Mid-stream urine (MSU) samples collected for culture and sensitivity testing, sent to the laboratory during the period of study were included in this study. The samples were inoculated onto blood agar and MacConkey agar, incubated at 37°C for 24 hours. Identification of organisms by biochemical tests and antibiotic susceptibility testing were done by standard microbiological methods. Results: Out of 7825 samples, 3832 showed significant bacteriuria, of which 50% (1924/3832) were females. Escherichia coli was the most common pathogen isolated, which accounts for 41% followed by Klebsiella spp. (27%), Staphylococcus aureus (7%), Proteus spp. (7%), Acinetobacter spp. (5%), Pseudomonas spp. (4%), Enterobacter spp. (4%), Citrobacter spp.(4%), and Serratia spp. (0.9%). The antimicrobial susceptibility testing of Staphylococcus aureus showed 33% were Methicillin Resistant Staphylococcus aureus. The antimicrobial susceptibility pattern of gram negative bacilli showed high resistance to cephalosporins followed by carbapenems. Among gram negative bacilli, Klebsiella spp. showed 36% extended spectrum beta lactamases (ESBL) production. Conclusions: This study determines the trends in antimicrobial sensitivity patterns of uropathogens. It is helpful in the formulation of local antibiotic policy for the hospital and assist clinicians in the rational choice of antibiotic therapy to prevent misuse or overuse of antibiotics so as to prevent emergence of multi drug resistant pathogens.

scholarly journals Antimicrobial susceptibility pattern of Gram negative bacteria isolated from intensive care units in Al-Ahsa, Kingdom of Saudi Arabia

2018 ◽  
Vol 12 (31) ◽  
pp. 747-753 ◽  
Author(s):  
Badger-Emeka Lorina ◽  
Abdulhadi Al-Sultan Abdulrahman ◽  
Sami Alrashed Abdullatif ◽  
Sami Alhaddad Mohammed ◽  
Khalifah Al-Barjas Afnan
Keyword(s):  
Saudi Arabia ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Antimicrobial Susceptibility ◽  
Gram Negative Bacteria ◽  
Susceptibility Pattern ◽  
Kingdom Of Saudi Arabia ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern

AEROBIC BACTERIOLOGICAL PROFILE WITH ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF PUS SAMPLES AT A TERTIARY CARE HOSPITAL IN JAIPUR

2021 ◽  
pp. 65-67
Author(s):  
Hemendra K Sharma ◽  
Niketa Gupta ◽  
Mahesh Yadav ◽  
Aruna Vyas ◽  
Rajni Sharma
Keyword(s):  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Diffusion Method ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Gram Positive ◽  
Gram Negative ◽  
Inappropriate Use ◽  
Antimicrobial Susceptibility Pattern

Background: Pyogenic infections can be caused by various microorganisms and may co-exist as poly microbial infections which require antibiotic therapy. The inappropriate use of antibiotics has led to major problems of MDRO's contributing to morbidity and mortality. Even though the bacteriological prole of pus samples in many studies remain the same, antimicrobial susceptibility pattern of these isolates has shown a lot of variation. This study was conducted to assess bacteriological prole of pus samples and their antimicrobial susceptibility pattern Materials and Methods:Aretrospective study was carried out from April to June 2021. 540 pus culture aerobic bacterial isolates were included. The samples were cultured on Blood and MacConkey agar. After aerobic incubation at 37oC for 18-24 hrs, organisms were identied by conventional bacteriology methods as per laboratory protocol and antimicrobial susceptibility was tested by Kirby Bauer disc diffusion method as per CLSI 2020 guideline. Results: Out of 540 pus isolates , 452(83.7%)were gram negative bacili and 88(16.3%) were gram positive cocci Pseudomonas spp. 173(31.9%), was most common gram negative isolate while S.. aureus 66(12.19%) was most common Gram positive isolate. Most of gram negative isolates were susceptible to Imipenem and Polymyxin and gram positive isolates to vancomycin and linezolid . Conclusion: To combat resistance irrational use of antibiotics should be avoided. Also regular surveillance helps in implementing better therapeutic strategies to reduce morbidity and mortality

Antibiogram of Gram Negative Uropathogens in a Tertiary Care Hospital

2021 ◽  
Vol 8 (2) ◽  
pp. 80-84
Author(s):  
Milind Davane ◽  
Sanjivani Mundhe
Keyword(s):  
Urinary Tract ◽  
Antimicrobial Susceptibility ◽  
Hospitalized Patients ◽  
Health Concern ◽  
Diffusion Method ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern ◽  
Tract Infections ◽  
Klebsiella Spp

Background: Globally, urinary tract infection (UTI) is considered a major public health concern and the second most common bacterial infection affecting individuals of different ages worldwide. Urinary tract infections (UTIs) are caused by multiplicity of microorganisms. The chronicity of different bacterial isolates and their propensity to various antibiotics may differ widely, particularly in hospitalized patients, that makes the study of susceptibility pattern mandatory for a proper selection of antibiotics. Objective: To evaluate antimicrobial susceptibility pattern of the Gram negative organisms isolated from urine cultures of hospitalized patients. Material and Methods: A total of 500 urine samples from hospitalized patients which showed significant bacteriuria were studied. Samples were inoculated on Blood agar and MacConckey agar. Further identification and study of organisms was done by standard Microbiological methods. Antimicrobial Susceptibility pattern was studied by Modified Kirby- Bauer’s disc diffusion method with the panel of 15 drugs as per Clinical Laboratories Standard Institute (CLSI) guidelines. Results: UTIs were found more common in females 290 (58%). Commonest organism found was Escherichia coli 260 (52%) followed by Klebsiella spp. 120 (24%), Pseudomonas spp. 40 (8%), Proteus spp. 38 (7.6%), Citrobacter spp. 25 (5%) and Acinetobacter spp. 17 (3.4%). Majority of the strains were found sensitive to nitrofurantoin followed by amikacin, piperacillin-tazobactam and cotrimoxazole. Commonly prescribed fluroquinolones were found least effective for treatment of UTI. All the strains were found sensitive to imipenem. Extended spectrum beta lactamase (ESBL) was noted in E.coli and in Klebsiella spp. Conclusion: To discourage the indiscriminate use of antibiotics and to prevent further development of bacterial drug resistance, proper knowledge of susceptibility pattern of uropathogens in particular area is very important before prescribing any empirical antibiotic therapy.

Sign in / Sign up

Export Citation Format

Share Document