Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women with ureteral stones and hydronephrosis

2012 ◽  
Vol 6 (12) ◽  
Author(s):  
Murat Atar
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Drug Susceptibility ◽  
Ureteral Stones ◽  
Susceptibility Pattern ◽  
Drug Susceptibility Pattern

scholarly journals Urinary Tract Infection and Drug Susceptibility Pattern in Patients of a Medical College Hospital in Bangladesh

2014 ◽  
Vol 4 (1) ◽  
pp. 21-25
Author(s):  
Rafiul Alam Khan ◽  
Md Fazhul Karim
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Isolation And Identification ◽  
College Hospital ◽  
Klebsiella Species ◽  
Medical College ◽  
Single Organism

Background: Urinary tract infection (UTI) is a common and frequently encountered serious morbidity that afflicts the tool not only to all segments of human population but also results in increasing antibiotic resistance due to persistence and mismanagement of the ailment. The present study aimed to ascertain the current situation of antimicrobial resistance of urinary tract infection. Objectives: To find out pyuria by direct microscopy, isolation and identification of the organisms by culture and to know the susceptibility pattern of organisms causing urinary tract infection. Materials and Methods: A total of 180 midstream urine samples were subjected to aerobic bacteriologic culture in the department of Microbiology, Cox’s Bazar Medical College and 250-bedded Sadar Hospital, Cox’s Bazar during the period of March to October 2012. Specimens were collected from hospitalized and outdoor patients of different age and sex groups. All specimens were examined by routine microscopy to find out significant pyuria (>5 pus cells/HPF). Strict aseptic precautions were taken all through the culture system. Results: Out of 180 specimens, 101 (56.11%) culture yielded significant growth of single organism and 79 (43.89%) yielded no growth. The isolated organisms were E. coli 74.26%, Klebsiella species 12.87%, Enterococci 4.95%, Staphylococcus saprophyticus 3.96%, Pseudomonas species 1.98% and Proteus species 1.98%. The highest sensitivity was shown by imipenem (100%) followed by ceftriaxone (65%), azithromycin (65%), ciprofloxacin (60%) and less sensitive to amoxycillin, cotrimoxazole, cephradine and nalidixic acid ranging 15–30%. Conclusion: The findings of the present study recommends that UTI should be treated by selective antibiotics obtained from culture and sensitivity test to minimize increasing trend of drug resistance. DOI: http://dx.doi.org/10.3329/jemc.v4i1.18064 J Enam Med Col 2014; 4(1): 21-25

scholarly journals Drug Susceptibility Pattern and Associated Factors of Bacteria Isolated from Urinary Tract Infection among Pregnant Women Attending Antenatal Care in Teaching Hospital, Southeast Ethiopia

2021 ◽  
Author(s):  
Eshetu Nigussie ◽  
Meseret Mitiku ◽  
Alelign Tasew ◽  
Biniyam sahiledengel ◽  
Damtew Solomon ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Previous History ◽  
Urine Samples ◽  
P Value ◽  
Susceptibility Pattern ◽  
Southeast Ethiopia ◽  
Significant Bacteriuria

Abstract Background: Urinary tract infection is caused by bacteria from the digestive tract which climbs the opening of the urethra and begins to multiply to cause infection. This study aimed to assess the bacterial profile and antibiotic susceptibility pattern and associated risk factors among pregnant women in Madda Walabu University Goba Referral Hospital, Southeast Ethiopia. Methods: An institution-based cross-sectional study was conducted from June-August, 2019. A total of 234 pregnant women were enrolled; data were collected using a structured questionnaire by a trained interviewer. Urine samples were collected from all pregnant women and culture on cysteine lysine electrolytes deficiency medium. Data were analyzed using SPSS 20.0. Descriptive statistics were used to explain the study participants with relevant variables. Logistic regression was used for data comparison. P-value <0.05 was accepted as statistically significant. Results: The overall prevalence of UTI was 23.9% among both asymptomatic and symptomatic groups. Of this screened midstream urine samples showed that 16% and 32.2%, had significant bacteriuria in the asymptomatic and symptomatic groups respectively. The prevalence of UTI was significantly associated with previous history of catheterization and urinary tract infection. E. coli was the most frequently isolated organism (42.9%) followed by coagulase-negative Staphylococcus (26.8%), and S. aureus (12.5%). Gram-negative and Gram-positive bacteria accounted for (59%) and (41%) respectively.Conclusion: Significant bacteriuria has been observed from both symptomatic and asymptomatic pregnant women. The majority of the isolates were resistant to commonly prescribed antibiotics. This calls for an early screening of all pregnant women for UTI and those found to be infected need treatment.

scholarly journals Etiology and prevalence of urinary tract infections among pregnant women in Kerala

2018 ◽  
Vol 5 (8) ◽  
pp. 3298
Author(s):  
Srinath M. P. ◽  
Shajina M. ◽  
Fasalu Rahiman O. M.
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Drug Susceptibility ◽  
Premature Delivery ◽  
Fetal Mortality ◽  
Microbiological Analysis ◽  
Tract Infections ◽  
In Pregnancy

Background: Infectious disease such as urinary tract infection was found very commonly during all pregnancies. Chronic renal failure, pyelonephritis, preeclampsia, anemia, fetal mortality and premature delivery are the common complication associated with UTI in pregnancy. Hence the management and prevention of UTI in pregnancy is the crucial factor for the sustained pregnant period. It is more important for a clinician to recognize the pathogenic factor for UTI and its sensitivity profile for planning an effective treatment for infected patients. Hence the present study was designed to identify the pathogenic agents of UTI among pregnant women and to find out the drug susceptibility patterns of the isolated organism against commonly prescribed antibioticsMethods: A prospective analysis was carried out by collecting urine from the 210 patients, the sample was also processed for antimicrobial drug susceptibility testing.Results: A positive report was seen in 26 cases with 13.4% of incident rate. Escherichia coli 14 (53.8%), Klebsiella species 23.07%, Enterococcus species 7.69%, Staphylococcus aureus 3.84%, Proteus 3.84%, Pseudomonas aeroginosa 3.84%, Streptococcus pyogenes 3.84% were the most common isolate found in the present population. The isolated pathogens were sensitive to Ceftazidime, Cefotaxime, Ciprofloxacin, Gentamicin, and Amikacin.Conclusions: It is there for recommended that routine microbiological analysis and antibiotic sensitivity test of urine samples of pregnant women must be carried out before the administration of drugs for better treatments and managements of urinary tract infection.

scholarly journals Prevalence and Antimicrobial Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Hargeisa Group Hospital, Hargeisa, Somaliland

2021 ◽  
Author(s):  
Abdikhaliq Hussein Ali ◽  
Dawit Yihdego Reda ◽  
Moges Desta Ormago
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Previous History ◽  
Susceptibility Pattern ◽  
Cross Sectional ◽  
Antimicrobial Susceptibility Pattern ◽  
History Of

Abstract The aim of this study was to determine the prevalence, antimicrobial susceptibility pattern and associated factors of urinary tract infection (UTI) among pregnant women attending Hargeisa Group Hospital (HGH), Hargeisa, Somaliland. A cross-sectional study was conducted at HGH, Hargeisa, Somaliland and participants were selected by systematic random sampling technique. Clean catch midstream urine samples were collected from 422 participants and cultured and antimicrobial susceptibility pattern was determined for the isolates. Univariable and multivariable logistic regression analyses were utilized to identify the independent risk factors for UTI The prevalence of UTI was 16.4 % (95% CI: 13.3–19.9). The predominant bacteria isolate was E. coli (43.5%). Gram negative bacteria were resistant to ampicillin (96%) and tetracycline (71.4%) and Gram-positive bacteria were also resistant to ampicillin (90%), tetracycline (55%). Multidrug resistance was observed in 89.9% of bacterial isolated. No formal education participants were 3.18 times, previous history of catheterization had 3.22 times and previous history of UTI had 3.73 times more likely to develop UTI than their counterparts respectively. Culture and susceptibility test is vital for appropriate management of UTI in the study area.

scholarly journals Bacterial Profile and Antibiotic Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Antenatal Care at a Tertiary Care Hospital in Southern Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Ashenafi Tula ◽  
Abraham Mikru ◽  
Tsegaye Alemayehu ◽  
Beyene Dobo
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Klebsiella Pneumoniae ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Southern Ethiopia ◽  
Susceptibility Pattern ◽  
Gram Negative

Background. Urinary tract infection is one of the most common bacterial infections encountered in pregnant women with significant morbidity. This study aimed to determine the bacterial profile and its antimicrobial susceptibility pattern of urinary tract infection among pregnant women attending antenatal care (ANC) at a Hawassa University Comprehensive Specialized Hospital (HUCSH), Southern Ethiopia. Method. A cross-sectional study was conducted in which consecutive pregnant women enrolled in the study from March to June 2019. The structured questionnaire used to collect sociodemographic and clinical data in a face-to-face interview. Midstream urine was collected from pregnant women using sterile containers. Culture and sensitivity were performed using a standard operating procedure of the microbiology laboratory. Data entry and analysis were conducted using the statistical package for social sciences (SPSS) version 20. Descriptive and logistic regression was used to conduct the output of the data. The odds ratio at 95% confidence interval was considered as a statistically significant association with a p value <0.05. Result. The overall magnitude of urinary tract infection in this study was 7.8% (4.7–10.8%). Escherichia coli was found to be the most frequently isolated (47.8%), followed by Klebsiella pneumoniae (17.4%), Staphylococcus aureus (8.7%), Klebsiella ozaenae, Klebsiella rhinoscleromatis, Citrobacter spp., Salmonella group A, Staphylococcus saprophyticus, and Enterobacter cloacae each (4.3%). Gram-negative bacteria were sensitive to 78.3%, 91.3%, and 100% of ciprofloxacin, gentamicin, and nitrofurantoin, respectively. Gram-positive bacteria were sensitive to clindamycin (100%), gentamicin (100%), and nitrofurantoin (100%) and fully resistant to ceftriaxone (100%) and cefuroxime (100%). There is no statistically significant association (p < 0.05) between the risk factor of urinary tract infection and UTI. Conclusion. The overall prevalence of urinary tract infection among pregnant women attending antenatal care was 7.8%. Escherichia coli were the dominant isolate followed by Klebsiella pneumoniae. Gram-negative isolates are highly sensitive to ciprofloxacin, gentamicin, nitrofurantoin, and ceftriaxone and Gram-positive isolates to gentamicin, clindamycin, and nitrofurantoin. Most of the bacteria are resistant to cotrimoxazole and cefuroxime. There is no statistically significantly associated variable. Screening for the presence of urinary tract infection during pregnancy will improve the quality of antenatal care further reducing complication. The above antibiotics can be prescribed based on the side effect to pregnant women in case empirical treatment is mandatory in the study area.

scholarly journals Drug Susceptibility Pattern and Associated Factors of Bacteria Isolated from Urinary Tract Infection among Pregnant Women Attending Antenatal Care in Teaching Referral Hospital, Southeast Ethiopia

2021 ◽  
Vol 5 (2) ◽  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Southeast Ethiopia ◽  
Significant Bacteriuria ◽  
In Pregnancy

Background: Urinary tract infection (UTI) is caused by bacteria from the digestive tract which climbs the opening of the urethra and begins to multiply to cause infection. UTI in pregnancy is associated with significant morbidity for both mother and baby. In most developing countries including Ethiopia, screening for UTI in pregnancy is not considered an essential part of Antenatal Care. This study aimed to assess the bacterial profile and antibiotic susceptibility pattern and associated risk factors among pregnant women in Madda Walabu University Goba Referral Hospital, Southeast Ethiopia. Methods: An institution-based cross-sectional study was conducted from June-August, 2020 . A total of 234 pregnant women were enrolled; data were collected using a structured questionnaire by a trained interviewer. Urine samples were collected from all pregnant women and culture on cysteine lysine electrolytes deficiency medium. Data were analyzed using SPSS 20.0. Descriptive statistics were used to explain the study participants with relevant variables. Logistic regression was used for data comparison. P-value <0.05 was accepted as statistically significant. Results: The overall prevalence of UTI was 23.9% among both asymptomatic and symptomatic groups. Of this screened midstream urine samples showed that 16% and 32.2%, had significant bacteriuria in the asymptomatic and symptomatic groups respectively. The prevalence of UTI was significantly associated with previous history of catheterization and urinary tract infection (p<0.05). E. coli was the most frequently isolated organism (42.9%) followed by coagulase-negative Staphylococcus (26.8%), and S. aureus (12.5%). Gram-negative and Gram-positive bacteria accounted for (59%) and (41%) respectively. Gram-negative isolates showed resistance to ampicillin, naldixic acid and trimethoprim/sulfamethoxazole. Also, all Gram-negative bacterial isolates revealed a high level of resistance against trimethoprim/sulfamethoxazole. Conclusion: Significant bacteriuria has been observed from both symptomatic and asymptomatic pregnant women. The majority of the isolates were resistant to commonly prescribed antibiotics. This calls for an early screening of all pregnant women for UTI and those found to be infected need treatment with an appropriate drug to avoid complications.

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