scholarly journals Gibberellic acid, amino acids (glycine and L-leucine), vitamin B2 and zinc as factors affecting the production pigments by Monascus purpureus in a liquid culture using response surface methodology

2014 ◽  
Vol 13 (13) ◽  
pp. 1484-1490 ◽  
Author(s):  
Baneshi Fateme ◽  
Azizi Majid ◽  
Saberi Mohsen ◽  
Farsi Mohammad
Keyword(s):  
Amino Acids ◽  
Response Surface Methodology ◽  
Gibberellic Acid ◽  
Response Surface ◽  
Liquid Culture ◽  
Monascus Purpureus ◽  
Vitamin B2 ◽  
Factors Affecting

scholarly journals Analysis of Factors Affecting Miscanthus Pellet Production and Pellet Quality using Response Surface Methodology

BioResources ◽  
2014 ◽  
Vol 9 (2) ◽  
Author(s):  
Youn-Ho Moon ◽  
Jungwoo Yang ◽  
Bon-Cheol Koo ◽  
Jong-Woong An ◽  
Young-Lok Cha ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Pellet Quality ◽  
Factors Affecting ◽  
Pellet Production

Enhancement of protein production by microalgae Dunaliella salina under mixotrophic conditions using response surface methodology

RSC Advances ◽  
2015 ◽  
Vol 5 (48) ◽  
pp. 38141-38151 ◽  
Author(s):  
S. Kadkhodaei ◽  
S. Abbasiliasi ◽  
T. J. Shun ◽  
H. R. Fard Masoumi ◽  
M. S. Mohamed ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Transgene Expression ◽  
Protein Production ◽  
Dunaliella Salina ◽  
Schematic Diagram ◽  
Factors Affecting ◽  
Enhancement Of Protein Production ◽  
Mixotrophic Conditions

Schematic diagram of the upstream and downstream factors affecting transgene expression.

scholarly journals Optimization of Soybean Meal Fermentation for Aqua-Feed with Bacillus subtilis natto Using the Response Surface Methodology

Fermentation ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 306
Author(s):  
Yukun Zhang ◽  
Manabu Ishikawa ◽  
Shunsuke Koshio ◽  
Saichiro Yokoyama ◽  
Serge Dossou ◽  
...  
Keyword(s):  
Amino Acids ◽  
Response Surface Methodology ◽  
Bacillus Subtilis ◽  
Response Surface ◽  
Layer Thickness ◽  
Soybean Meal ◽  
Essential Amino Acids ◽  
Total Phenolic ◽  
Bacillus Subtilis Natto ◽  
Substrate Ratio

This study aimed to improve the nutritional value of soybean meal (SBM) by solid-state fermentation (SSF) using Bacillus subtilis natto (B. s. natto) to overcome the limitations of SBM usage in aquafeed. The response surface methodology (RSM) was employed to explore the relationships of fermentation conditions, such as temperature, time, water-substrate ratio, and layer thickness, on the degree of protein hydrolysis (DH) and the crude protein (CP) content. The optimum conditions for achieving the higher DH (15.96%) and CP (55.76%) were 43.82 °C, 62.32 h, 1.08 of water-substrate ratio, and a layer thickness of 2.02 cm. CP and DH in the fermented soybean meal (FSM) increased by 9.8% and 177.1%, respectively, and crude fiber decreased by 14.1% compared to SBM. The protein dispersibility index (PDI) decreased by 29.8%, while KOH protein solubility (KPS) was significantly increased by 17.4%. Flavonoids and total phenolic acid content in FSM were increased by 231.0% and 309.4%, respectively. Neutral protease activity (NPA) also reached a high level (1723.6 U g−1). Total essential amino acids (EAA) in FSM increased by 12.2%, higher than the 10.8% increase of total non-essential amino acids (NEAA), while the total free amino acids content was 12.76 times higher than that of SBM. Major anti-nutritional factors in SBM were significantly reduced during the process, and almost all SBM protein macromolecules were decomposed. Together with the cost-effectiveness of SSF, B. s. natto-fermented SBM products have great potential to improve the plant composition and replace high-cost ingredients in aquafeed, contributing to food security and environmental sustainability.

scholarly journals Optimization of the Production of Lovastatin from Aspergillus sclerotiorum PSU- RSPG178 under Static Liquid Culture using Response Surface Methodology

2019 ◽  
Vol 48 (1) ◽  
pp. 93-102
Author(s):  
Sudarat Suwannarat ◽  
Jutarut Iewkittayakorn ◽  
Yaowapa Sukpondma ◽  
Vatcharin Rukachaisirikul ◽  
Souwalak Phongpaichit ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Liquid Culture ◽  
Aspergillus Sclerotiorum

Performance Optimization of Cement-Fly Ash Grouting Material Based on Response Surface Methodology

2021 ◽  
Vol 1036 ◽  
pp. 337-344
Author(s):  
Lin Lin Wang ◽  
Xiang Bin Xu ◽  
Qing Song Zhang ◽  
Shi Yi Li
Keyword(s):  
Response Surface Methodology ◽  
Fly Ash ◽  
Response Surface ◽  
Performance Optimization ◽  
Reducing Agent ◽  
Sand Fly ◽  
Hydration Reaction ◽  
Factors Affecting ◽  
And Performance ◽  
Grouting Materials

Filling grouting is effective to control the overlying strata movement and surface subsidence in mining and tunnel engineering.Grouting material is used in grouting reinforcement projects. In this experiment,based on the mechanical properties of grouting materials, Expert Design and response surface methodology (RSM) is used to optimize the mix proportion of grout materials. The sand-fly ash ratio ,water reducing agent addition are researched as variables, and the 3D response surface is established between the factors and the performance indicators. Microstructure explains the mechanism of factors affecting performance indicators.The results show the relationship between factors and performance can be well fitted by RSM.The order of significance on compressive strength and solidification ratio is sand-fly ash ratio＞water reducing agent addition and the order of significant on viscosity is water reducing agent addition＞sand-fly ash ratio.Response surface methodology accurately describes the functional relationship between the target value and the design variables.Microstructure shows hydration reaction and the secondary hydration reaction of fly ash will be carried out after cement-fly ash mixed, and the addition of fly ash is especially important for grout material properties.

To Enhance the Production of Human-Like Collagen II by Amino Acid Addition Using Response Surface Methodology

2011 ◽  
Vol 393-395 ◽  
pp. 1054-1059
Author(s):  
Lei Guo ◽  
Yan E Luo ◽  
Dai Di Fan ◽  
Ru Xu
Keyword(s):  
Amino Acids ◽  
Response Surface Methodology ◽  
Response Surface ◽  
Fermentation Broth ◽  
Biological Activities ◽  
Basic Unit ◽  
Control Group ◽  
Cultivation Condition ◽  
Protein Molecules ◽  
Maximal Production

Amino acids, the basic unit of protein molecules, are closely related with biological activities. In order to enhance the expression of human-like collagen (HLC), amino acids were added into fermentation broth, and response surface methodology (RSM) to optimize the categories and the concentration of amino acids. The results of PB-design showed that only the dosage of alanine and glutamate had significant effects on the production of HLC. Quadratic polynomial models were established after analyzing the results of CCD-design. The optimal concentration of alanine and glutamate were 3.78gL-1、and 2.52g•L-1 respectively. Under the optimal cultivation condition the maximal production of human-like collagen could be up to 0.292g•L-1 which was 11.45% higher than that of the control group 0.262g•L-1 (the highest production of the former study).

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