scholarly journals Banding ligation or beta-blockers for primary prevention of variceal bleeding?

Medwave ◽  
2016 ◽  
Vol 16 (Suppl5) ◽  
pp. e6564-e6564 ◽  
Author(s):  
Petre Cotoras Viedma ◽  
Roberto Candia
Keyword(s):  
Primary Prevention ◽  
Variceal Bleeding ◽  
Beta Blockers ◽  
Banding Ligation

scholarly journals Is banding ligation for primary prevention of variceal bleeding as effective as beta-blockers, and is it safe?

Hepatology ◽  
2005 ◽  
Vol 43 (1) ◽  
pp. 196-197 ◽  
Author(s):  
Christos Triantos ◽  
Jiannis Vlachogiannakos ◽  
Spilios Manolakopoulos ◽  
Andrew Burroughs ◽  
Alec Avgerinos
Keyword(s):  
Primary Prevention ◽  
Variceal Bleeding ◽  
Beta Blockers ◽  
Banding Ligation

Banding ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children

2013 ◽  
Author(s):  
Juan Cristóbal Gana ◽  
Lorena I Cifuentes ◽  
Jaime Cerda ◽  
Luis A Villarroel del Pino ◽  
Alfredo Peña ◽  
...  
Keyword(s):  
Variceal Bleeding ◽  
Beta Blockers ◽  
Primary Prophylaxis ◽  
Banding Ligation

scholarly journals Meta-analysis: beta-blockers versus banding ligation for primary prophylaxis of esophageal variceal bleeding

2012 ◽  
Vol 11 (3) ◽  
pp. 369-383 ◽  
Author(s):  
Natalie Funakoshi ◽  
Yohan Duny ◽  
Jean-Christophe Valats ◽  
Frédérique Ségalas-Largey ◽  
Nicolas Flori ◽  
...  
Keyword(s):  
Variceal Bleeding ◽  
Beta Blockers ◽  
Meta Analysis ◽  
Primary Prophylaxis ◽  
Esophageal Variceal ◽  
Esophageal Variceal Bleeding ◽  
Banding Ligation

scholarly journals Comparison of endoscopic variceal ligation and beta-blocker (carvedilol) plus nitrate for the primary prevention of variceal bleeding

2017 ◽  
Vol 4 (4) ◽  
pp. 1053
Author(s):  
Anilesh Kumar Singh Yadav ◽  
Priyadarshi B. P. ◽  
Gupta A. C. ◽  
Mahendra Singh ◽  
Ashok Kumar Verma ◽  
...  
Keyword(s):  
Primary Prevention ◽  
Combination Therapy ◽  
Beta Blocker ◽  
Variceal Bleeding ◽  
Beta Blockers ◽  
Isosorbide Mononitrate ◽  
P Value ◽  
Endoscopic Sclerotherapy ◽  
Endoscopic Variceal Ligation ◽  
Promising Alternative

Background: Esophageal variceal bleed is a major problem in patients with cirrhosis. Endoscopic sclerotherapy and variceal ligation are effective in stopping bleeding in up to 90% of patients. Beta-blocker (Carvedilol) + Isosorbide Mononitrate are promising alternative to other nonselective beta blocker or endoscopic band ligation for the prevention of first variceal bleeding of medium to large varices, which needs to be further explored.Methods: The present study was an observational study in 200 patients at LLR and Associated Hospitals PG Department of Medicine GSVM Medical College, Kanpur. After randomization 120 patients underwent for Endoscopic Variceal ligation and 80 patients were put on beta-blocker (Carvedilol) + Isosorbide Mononitrate therapy for the primary prevention of variceal bleeding.Results: Most common cause of portal hypertension was liver cirrhosis (in carvedilol plus isosorbide mononitrate group 70%, and it was 85%. in EVL group. Bleeding in patients of carvedilol plus isosorbide mononitrate was significantly lower (23.75%) than patients of EVL (60%) group. Reduction in bleeding was statistically highly significant (p value < 0.05). Mortality among patients receiving combination therapy with carvedilol plus isosorbide mononitrate was (12.5%) comparison to EVL (21.66%). Reduction in mortality was statistically not significant. (p value >0.05). Adverse effects were significantly lower among patients receiving combination therapy with carvedilol plus isosorbide mononitrate (38.75%) than patients of EVL (86.66%) group.Conclusions: Both EVL and beta-blockers may be considered first-line treatment to prevent first variceal bleeding, whereas beta-blockers (carvedilol) plus isosorbide mononitrate may be the best choice for the prevention of re-bleeding.

Sign in / Sign up

Export Citation Format

Share Document