scholarly journals Lateral retropharyngeal node metastasis from squamous cell carcinoma of the tongue

2012 ◽  
Vol 24 (4) ◽  
pp. 165-172
Author(s):  
Yukinori Kimura ◽  
Tomomi Hanazawa ◽  
Tomohiro Okano ◽  
Taro Irie ◽  
Kenji Mishima ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Node Metastasis ◽  
Retropharyngeal Node ◽  
Carcinoma Of The Tongue

scholarly journals Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue

2017 ◽  
Vol 22 (02) ◽  
pp. 136-140 ◽  
Author(s):  
Sadaf Ahmed ◽  
Montasir Junaid ◽  
Sohail Awan ◽  
Maliha Kazi ◽  
Hareem Khan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Early Stage ◽  
Cervical Lymph Node Metastasis ◽  
Nodal Metastasis ◽  
Tumor Thickness ◽  
Node Metastasis ◽  
Carcinoma Of The Tongue

Introduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors. However, for early-stage carcinomas of the tongue, the management remains controversial. Several studies have indicated that early-stage cancers have a high chance of occult cervical node metastasis, which, if left untreated, can greatly affect the prognosis. Certain parameters can help identify patients with occult cervical node metastases, and can avoid unnecessary neck dissection in node negative patients. Tumor thickness is one such objective parameter. Objective To estimate the frequency of cervical lymph node metastasis in patients with early-stage, node-negative (N0) squamous cell carcinoma of the tongue. Methods In-patient hospital data was reviewed from January 2013 until March 2014, and 78 patients who underwent primary resection of the tumor and neck dissection for biopsy-proven, early stage squamous cell carcinoma of the tongue were included. Data such as tumor thickness, tumor differentiation and presence of occult nodal metastasis in the surgical specimen were gathered from the histopathology reports. The frequency of subclinical cervical lymph node metastasis in patients with early-stage squamous cell carcinoma of the tongue was estimated. Results A total of 69% of the patients with tumor thicknesses > 5 mm had tumor metastases in the neck nodes, while 100% of the patients with tumor thicknesses < 5 mm had no neck nodal metastasis. Conclusion A tumor thickness > 5 mm is significantly associated with subclinical metastasis, and prophylactic neck dissection is warranted in such cases.

scholarly journals Use of NRP1, a novel biomarker, along with VEGF-C, VEGFR-3, CCR7 and SEMA3E, to predict lymph node metastasis in squamous cell carcinoma of the tongue

2016 ◽  
Vol 36 (5) ◽  
pp. 2444-2454 ◽  
Author(s):  
Hani Al-Shareef ◽  
Shin-Ichiro Hiraoka ◽  
Noriaki Tanaka ◽  
Yosuke Shogen ◽  
Atsushi-Doksa Lee ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Node Metastasis ◽  
Carcinoma Of The Tongue
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