scholarly journals Palmoplantar Pustulosis and Allergies: A Systematic Review

2019 ◽  
pp. 105-110 ◽  
Author(s):  
Alexandra M.G. Brunasso Vernetti ◽  
Matteo Puntoni ◽  
Cesare Massone

Background: In 2007 the International Psoriasis Council considered palmoplantar pustulosis (PPP) a condition separate from psoriasis, and several authors maintain that PPP is a reactive process to metal contact allergies independent from psoriasis. Objectives: To evaluate the frequency of allergies and psoriasis in patients with PPP and to determine the role of allergens in PPP. Methods: A systematic search of the English databases (PubMed and Web of Science) from January 1964 to August 2018 to identify all patients affected by PPP and allergies and/or psoriasis. Results: In total, 16 publications describing a total of 519 patients with PPP were evaluated and 122 cases of concomitant PPP and metal allergy were found. The frequency of allergies among patients with PPP was 22.7%; between the identified allergens, 84.3% of cases correspond to metal allergies. In 65.1% of metal allergies, an improvement in PPP was seen after withdrawal of contact. The concomitant presence of psoriasis was recorded in 18% of the cases. Conclusion: There is some evidence to support the association of PPP with metal allergies but also with psoriasis, suggesting the role of metal allergens as a trigger factor in patients with PPP.

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3872
Author(s):  
Małgorzata Styczewska ◽  
Małgorzata A. Krawczyk ◽  
Ines B. Brecht ◽  
Konrad Haug ◽  
Ewa Iżycka-Świeszewska ◽  
...  

Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a very rare pediatric neoplasm of neural crest origin. In most cases, it develops in infants as a localized tumor of the maxilla, and surgery is usually curative. In less than 10% of patients with inoperable, metastatic or persistently recurring MNTI, chemotherapy (CHT) may be considered; however, its role is still unclear. The aim of our study was to assess the efficacy of CHT in children with large, inoperable, metastatic and/or recurrent MNTI. Four such infants, treated with CHT in Polish and German centers of pediatric oncology, were presented. Additionally, a systematic literature search of the PubMed/MEDLINE, Scopus and Web of Science databases was performed, yielding 38 similar cases within the last 42 years. Neoadjuvant CHT, based mainly on the protocols for neuroblastoma, was often effective, allowing for complete delayed surgery in most cases. However, the role of adjuvant CHT in preventing recurrences after incomplete resection of MNTI remains unclear. Disseminated inoperable MNTI was almost universally associated with poor response to CHT and unfavorable outcome. Further investigations to elaborate standards of management in patients with inoperable, metastatic or persistently recurring MNTIs are necessary to improve outcomes.


Author(s):  
Fernanda Leite-Pereira ◽  
Filipa Brandao ◽  
Rui Costa

Purpose Diverse factors may influence travelers when choosing a hotel. Even though breakfast is often commented on in hotel and booking sites, its relative role in hotel selection is rarely studied. This paper aims to determine which attributes clients consider essential regarding the option towards a hotel and their hierarchy namely of breakfast. Design/methodology/approach A systematic review was performed in Scopus, ISI-Web of Science and Google Scholar, including relevant original manuscripts published in all languages between 1998 and 2018. Findings Out of 337 initial references, 25 manuscripts were included. Features related to facilities and services were considered in most manuscripts with 21 and 20 citations, respectively, as being the more relevant factors in hotel selection. Room and accommodation were ranked first as the most important characteristic regarding the option for a hotel, whereas breakfast was only referred to in two articles, published in 2015 and 2017, rated in the tenth and fourth positions, respectively. Research limitations/implications Breakfast seems to be addressed in recent published manuscripts, what may reflect a trend toward its evaluation in travelling experiences. More studies should address the relevance of breakfast and food to (diverse type of) costumers, and managers should also consider these factors when advertising their hotels. Originality/value To the best of the authors’ knowledge, this is the first systematic approach to this question, emphasizing the apparent contradiction of breakfast being often cited in booking sites and not adequately studied in tourism research.


2013 ◽  
Vol 47 (4) ◽  
pp. 799-812 ◽  
Author(s):  
Alexandre Emidio Ribeiro Silva ◽  
Ana Maria Baptista Menezes ◽  
Flavio Fernando Demarco ◽  
Fabiana Vargas-Ferreira ◽  
Marco Aurelio Peres

OBJECTIVE Identifying, through a systematic literature review, evidence of a possible association between obesity and dental caries. METHODS A search of articles published between 2005 and January 2012 was performed in the Medline/PubMed, LILACS and Web of Science databases. The quality of scientific evidence of the selected articles was assessed by the items proposed for observational studies in the Downs & Black instrument. RESULTS Initially, 537 references were found; after checking the titles and abstracts by two independent researchers, twenty-eight articles were selected for complete reading. Ten of them that assessed the primary and/or permanent dentition observed a positive association between obesity and dental caries and one study found an inverse association. According to the Downs & Black classification, thirteen articles with good scientific evidence were found. CONCLUSIONS The present review did not find sufficient evidence regarding the association between obesity and dental caries, and it did not clarify the possible role of diet and other possible effect modifiers on this association.


2019 ◽  
Vol 20 (2) ◽  
pp. 293 ◽  
Author(s):  
Milad Bastami ◽  
Jalal Choupani ◽  
Zahra Saadatian ◽  
Sepideh Zununi Vahed ◽  
Yaser Mansoori ◽  
...  

Recently extensive focus has been concentrated on the role of miRNAs in the initiation and progression of cardio-cerebrovascular diseases (CCDs) which constitute a range of conditions including cardiovascular diseases (CVDs, especially coronary artery disease (CAD)), congenital heart disease (CHD) and cerebrovascular diseases (CBVDs, especially the ischemic stroke (IS)). An increasing number of studies are evaluating the association between different miRNA polymorphisms and risk of CCDs, but results have been inconclusive. This study represents a comprehensive systematic review and meta-analysis of the association between miRNA polymorphisms and risk of CCDs. PubMed, Embase, Scopus, and Web of Science were queried to identify eligible articles. Odds ratios and 95% confidence intervals were used to assess the association of miRNA polymorphisms with CCD susceptibility. A total of 51 eligible articles evaluating the association of 31 miRNA polymorphisms were identified. Meta-analysis was performed for six miRNA polymorphisms. miR-146a rs2910164 (30 studies: 13,186 cases/14,497 controls), miR-149 rs2292832 (Nine studies: 4116 cases/3511 controls), miR-149 rs71428439 (Three studies: 1556 cases/1567 controls), miR-196a2 rs11614913 (20 studies: 10,144 cases/10,433 controls), miR-218 rs11134527 (Three studies: 2,322 cases/2,754 controls) were not associated with overall CCD. miR-499 rs3746444 was associated with CCD (20 studies: 9564 cases/8876 controls). In the subgroups, rs2910164 and rs3746444 were only associated with CVDs, especially CAD. In conclusion, the results support the existence of a role for miR-146a rs2910164 and miR-499 rs3746444 in determining susceptibility to CCDs, especially CAD.


2020 ◽  
Vol 10 (1) ◽  
pp. 43-60
Author(s):  
Piotr Teodorowski ◽  
Ruth Woods ◽  
Catriona Kennedy

Moving to a new country impacts on migrants’ mental health and wellbeing. There are over 3.6 million European Union citizens living in the United Kingdom. We conducted a systematic review of the qualitative literature to explore what is known about their mental health and wellbeing at the post-migration stage in pre-Brexit period. We searched five databases from 1st January 2009 to 19th February 2019; Web of Science, MEDLINE, CINAHL, SocIndex and Scopus for studies. Ten papers reporting nine studies were included in this review. Two themes were constructed; a narrative of adjustment and of employment realities. The former focuses on the process of settling in and the role of social connectedness. The latter concerns employment realities with included studies exploring the financial position and employment experiences of migrants. Findings indicate that we still know relatively little about the range of post-migration experiences among EU citizens and their implications for mental health


2021 ◽  
Vol 11 (9) ◽  
pp. 464
Author(s):  
Martín García-Parra ◽  
Francisca Negre ◽  
Sebastià Verger

Resilience is understood as interactive processes that strengthen the individual and the family in the face of the demands of adversity or vulnerable situation. Resilience is fostered from a psychopedagogical approach when practices are developed that assist in facing challenges positively, having life projects and developing academic potentialities. Thus, the objective of this systematic review of the literature is cartography programs that promote resilience in children, adolescents, or youths who are facing a challenging condition, such as a disease or disability. The PRISMA declaration was used to guide this systematic search. The databases consulted were Web of Science, Scopus, EBSCOhost, ERIC and Dialnet Plus. Open access articles were selected between 2016 and 2021. The selection resulted in 15 educational programs. The results indicate that there are several models for building resilience, such as ecosystem, family, community, and academic models. In conclusion, interdisciplinarity is a cross-cutting axis for enhancing resilience in vulnerable settings.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e20535-e20535
Author(s):  
Zahoor Ahmed ◽  
Shaha Nabeel ◽  
Arafat Ali Farooqui ◽  
Hassan Imtiaz ◽  
Aqsa Ashraf ◽  
...  

e20535 Background: In multiple myeloma (MM), translocation t(11;14) has shown higher expression of B Cell Lymphoma 2 protein (BCL2)- a target for Venetoclax (VEN). This review highlights the role of precision therapy with VEN in t(11;14) MM. Methods: A systematic search of PubMed, Cochrane, Web of Science and Clinicaltrials.gov was performed for use of VEN in MM from inception to 1/2/20. 5 out of 183 studies were finalized (N = 512). Results: Out of 500 relapsed refractory (R/R) MM patients, 97 had t(11;14) and 168 had high BCL2. VEN as monotherapy had encouraging responses in t(11;14) MM patients with high BCL2:BCL2L1 (Kumar 2017). VEN when combined with proteasome inhibitors (PIs) achieved promising results. VEN achieved superior results with carfilzomib and dexamethasone (d) (ORR 100%) in t(11;14) MM patients (Costa 2018) as compared to bortezomib (B) and d (ORR 94%) (Moreau 2017). With high BCL2, VEN-Bd achieved ORR of 84% (CR 35%, VGPR 73%) versus placebo (ORR 83%; VGPR 33%) (Bellini 2019). Conclusions: Venetoclax achieved superior responses in RRMM pts with t(11;14) and high BCL2 expression. Further studies are warranted. [Table: see text]


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Alejandro Lara-Bocanegra ◽  
M. Rocío Bohórquez ◽  
Jerónimo García-Fernández

PurposeThe main aim of this study was to analyze and establish the state of the question about entrepreneurship and intrapreneurship in sport, identify the role of innovation in both of them, as well as to determine the latest study trends and detect possible research niches.Design/methodology/approachA systematic review of the Web of Science, Scopus, PsycINFO, ERIC, SPORTDiscus and Dialnet databases was performed. The analysis of the selected texts allowed categorizing the entrepreneurship articles into subthemes: precursors of entrepreneurship, intention/orientation of entrepreneurship, different perspectives of entrepreneurship in sport and social entrepreneurship in sport. Of the 49 texts included in the review, only seven articles dealt with intrapreneurship, and they could not be classified into subtopics because the studies are scarce, diverse and with disparate themes.FindingsThe main findings show deficiencies in research on precursors/antecedents of entrepreneurial and intrapreneurial behavior, especially in relation to innovation, the importance of the political perspective on entrepreneurship in sport and formulation of behavior training programs for intrapreneurs.Originality/valueThis paper provides valuable and global information about entrepreneurship and intrapreneurship in sport, of which there were scattered or grouped data in some reviews.


2019 ◽  
Vol 11 (4) ◽  
pp. 1091 ◽  
Author(s):  
Sanchita Bansal ◽  
Isha Garg ◽  
Gagan Sharma

Social entrepreneurship has been recognized as a tool to attain sustainable development. This paper highlights the role of social entrepreneurship in triggering social change and attaining sustainable development. The paper contributes significantly to the existing literature by conducting a systematic review of extant works. To this end, we analyzed and reviewed 173 research papers from the Web of Science database. The results are presented in the form of descriptive findings and thematic discussion. The paper concludes by setting up the agenda for future researchers in the field.


2021 ◽  
Vol 17 ◽  
pp. 174480692110161
Author(s):  
Mari Aaroe Mannerak ◽  
Aslan Lashkarivand ◽  
Per Kristian Eide

Trigeminal neuralgia (TN) is a severe facial pain disease of unknown cause and unclear genetic background. To examine the existing knowledge about genetics in TN, we performed a systematic study asking about the prevalence of familial trigeminal neuralgia, and which genes that have been identified in human TN studies and in animal models of trigeminal pain. MedLine, Embase, Cochrane Library and Web of Science were searched from inception to January 2021. 71 studies were included in the systematic review. Currently, few studies provide information about the prevalence of familial TN; the available evidence indicates that about 1–2% of TN cases have the familial form. The available human studies propose the following genes to be possible contributors to development of TN: CACNA1A, CACNA1H, CACNA1F, KCNK1, TRAK1, SCN9A, SCN8A, SCN3A, SCN10A, SCN5A, NTRK1, GABRG1, MPZ gene, MAOA gene and SLC6A4. Their role in familial TN still needs to be addressed. The experimental animal studies suggest an emerging role of genetics in trigeminal pain, though the animal models may be more relevant for trigeminal neuropathic pain than TN per se. In summary, this systematic review suggests a more important role of genetic factors in TN pathogenesis than previously assumed.


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