scholarly journals Comparing the efficacy of intralesional triamcinolone acetonide with verapamil in treatment of keloids: A randomized controlled trial

2019 ◽  
pp. 4-9 ◽  
Author(s):  
Nasrin Saki ◽  
Raya Mokhtari ◽  
Farnoosh Nozari
Keyword(s):  
Controlled Trial ◽  
Randomized Study ◽  
Clinical Problem ◽  
Study Groups ◽  
Sufficient Evidence ◽  
Single Group ◽  
Randomized Controlled ◽  
Alternative Modality ◽  
Single Blind

Background: Keloid management remains a challenging clinical problem despite numerous therapies reported until now. The efficacy of corticosteroids in the treatment of keloids has been well established. The most commonly used corticosteroid is intralesional triamcinolone. Sporadic reports on the use of intralesional verapamil suggest its efficacy. Aim: Since there is not sufficient evidence to support the role of intralesional verapamil as an effective alternative modality, it was decided to undertake a randomized study to determine its efficacy as a treatment for keloids. Methods: A randomized, single-blind, single-group comparison with 15 patients (30 scars) was carried out to compare the effects of intralesional triamcinolone with verapamil injections. Injections were scheduled every 3 weeks accompanied by cryotherapy until complete flattening of the scar or maximum 8 sessions, whichever came earlier. Scar evaluation at each stage was done by serial photographic records as well as by Vancouver scar scale. Statistical analysis was done by Wilcoxon and Mann-Whitney U tests using SPSS version 19. Results: In both study groups there was a reduction in height and pliability at the end of the study. Better improvement in height and pliability was seen with triamcinolone in comparison with verapamil. However, a desired change in vascularity and pigmentation was not seen with either of the drugs. Conclusion: Verapamil is not as effective as triamcinolone in the treatment of keloids.

scholarly journals School girls and childbearing motives: A randomized clinical trial through hidden curriculum

2019 ◽  
Author(s):  
Zeinab Oshrieh ◽  
Afsaneh Keramat ◽  
Mohammad Shariati ◽  
Najmeh Tehranian ◽  
Elham Ebrahimi ◽  
...  
Keyword(s):  
Maternal Education ◽  
Hidden Curriculum ◽  
Controlled Trial ◽  
Government Schools ◽  
Fertility Decisions ◽  
Randomized Controlled ◽  
School Girls ◽  
Age Range ◽  
Single Blind

Background: Childbearing motives are considered as the primary stimulus of fertility and the importance of making fertility decisions in humans. Objective: The aim of this study is to determine the effect of a new form of interactional program on the childbearing motives of students. Materials and Methods: According to a well-defined, single-blind randomized controlled trial, we selected eight government schools in Tehran. Students in the age range of 7-12 yr and 16-18 yr (130 students in each school with a total number of 260) were selected for a series of intervention from storytelling to free discussion on a special subject through the concept of hidden curriculum. We evaluate the outcome with pretest-posttest based on the Miller childbearing motives questionnaire. One month after the last intervention, final evaluation took place. Results: The findings showed that after an intervention conducted in the best way, all positive scores were promoted while the negative ones declined. One the other hand, no matter what really the participant’s groups were, their total intention score got better. In this way, the total positive scores were significantly increased in the intervention groups (p = 0.000) Also, the students in high school significantly improved in positive scores and the negative score decreased in them. Conclusion: This study showed that the fundamental childbearing motives even with small interventions can be improved. Our intervention could improve the positive childbearing motives among school girls. In this regard, the role of some confounding factor such as the role of some confounding factors such as religious beliefs in family, maternal education is most important. Key words: Childbearing, Motive, School, Adolescents, Intention.

Role of preoperative pregabalin in reducing inhalational anesthetic requirements in abdominal hysterectomy: randomized controlled trial

2020 ◽  
Vol 86 (1) ◽  
Author(s):  
Nesrine A. El-Refai ◽  
Jehan H. Shehata ◽  
Ahmed Lotfy ◽  
Ahmed M. Elbadawy ◽  
Reham A. Abdel Rahman ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Abdominal Hysterectomy ◽  
Randomized Controlled ◽  
Inhalational Anesthetic

scholarly journals Patient Activation, Depressive Symptoms, and Self-Rated Health: Care Management Intervention Effects among High-Need, Medically Complex Adults

2021 ◽  
Vol 18 (11) ◽  
pp. 5690
Author(s):  
Cynthia F. Corbett ◽  
Kenn B. Daratha ◽  
Sterling McPherson ◽  
Crystal L. Smith ◽  
Michael S. Wiser ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Care Management ◽  
Controlled Trial ◽  
Patient Activation ◽  
Study Groups ◽  
Telephone Intervention ◽  
Management Intervention ◽  
Self Rated Health ◽  
Randomized Controlled ◽  
Complex Population

The purpose of this randomized controlled trial (n = 268) at a Federally Qualified Health Center was to evaluate the outcomes of a care management intervention versus an attention control telephone intervention on changes in patient activation, depressive symptoms and self-rated health among a population of high-need, medically complex adults. Both groups had similar, statistically significant improvements in patient activation and self-rated health. Both groups had significant reductions in depressive symptoms over time; however, the group who received the care management intervention had greater reductions in depressive symptoms. Participants in both study groups who had more depressive symptoms had lower activation at baseline and throughout the 12 month study. Findings suggest that patients in the high-need, medically complex population can realize improvements in patient activation, depressive symptoms, and health status perceptions even with a brief telephone intervention. The importance of treating depressive symptoms in patients with complex health conditions is highlighted.

Role of Chewing Gum in Reducing Postoperative Ileus after Reversal of Ileostomy: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Samiullah Bhatti ◽  
Yusra Jahangir Malik ◽  
Shabbar Hussain Changazi ◽  
Usman Ali Rahman ◽  
Awais Amjad Malik ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Postoperative Ileus ◽  
Controlled Trial ◽  
Chewing Gum ◽  
Randomized Controlled
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