scholarly journals Basal serum cortisol and adrenocorticotropic hormone levels in patients with atopic dermatitis

2017 ◽  
Vol 7 (4) ◽  
pp. 25-29 ◽  
Author(s):  
Zohreh Tehranchinia ◽  
Hoda Rahimi ◽  
Sara Lofti
2008 ◽  
pp. S193-S199
Author(s):  
K Šimůnková ◽  
L Stárka ◽  
M Hill ◽  
L Kříž ◽  
R Hampl ◽  
...  

The objective of this study was to evaluate the influence of low-dose combined oral contraception (COC) on basal and stimulated (1 microg ACTH test) levels of serum and salivary cortisol (F), cortisone and on basal serum cortisol binding globulin (CBG), adrenocorticotropic hormone (ACTH), dehydroepiadrosterone (DHEA) and calculated free cortisol in healthy young women. Three-month administration of COC resulted in 1) significant increase of basal (454.0+/-125.0 to 860.9+/-179.7 nmol/l) and ACTH-stimulated serum cortisol in 30th min (652.3+/-60.5 to 1374.1+/-240.6 nmol/l); 2) no significant change of basal (15.4+/-7.3 to 18.9+/-8.5 nmol/l) and ACTH-stimulated salivary cortisol at the 30th min (32.4+/-8.8 to 32.9+/-9.0 nmol/l); 3) no significant change of basal serum cortisone (38,8+/-7.68 to 45.2+/-24.2 nmol/l) and ACTH-stimulated cortisone at the 30th (34.8+/-10.9 to 47.0+/-35.7 nmol/l); 4) significant increase of basal ACTH (17.2+/-9.0 to 38.2+/-29.4 ng/l), CBG (991.0+/-161.0 to 2332.0+/-428.0 nmol/l), and 5) no significant change of basal DHEA (24.6+/-15.7 to 22.6+/-11.7 micromol/l) and calculated basal value for free cortisol (22.8+/-14.9 to 19.2+/-6.9 nmol/l). In conclusions, higher basal and ACTH-stimulated serum cortisol were found after three-month administration of COC, while basal and stimulated salivary cortisol were not significantly affected. Therefore, salivary cortisol can be used for assessment of adrenal function in women regularly using COC.


2007 ◽  
Vol 156 (5) ◽  
pp. 979-985 ◽  
Author(s):  
I.M. Haeck ◽  
L. Timmer-de Mik ◽  
E.G.W.M. Lentjes ◽  
E. Buskens ◽  
D.J. Hijnen ◽  
...  

2010 ◽  
Vol 14 (1) ◽  
pp. 13-18 ◽  
Author(s):  
F. Sule Afsar ◽  
Figen Isleten ◽  
Nihal Sonmez

Background: The hypothalamic-pituitary-adrenal axis has an important immunoregulatory role under stress, and stressmediated anxiety has been reported to be associated with alterations in immune functions and attenuated cortisol levels in atopic dermatitis (AD) patients. Objective: We investigated serum basal cortisol and anxiety levels in pediatric AD patients and compared them with those of controls. Methods: Basal serum cortisol levels were measured in 36 pediatric AD patients (aged 9–16 years) and 36 control subjects (aged 9–15 years). Anxiety was assessed by the trait anxiety subscale (TAI-C) of the State-Trait Anxiety Inventory for Children. The severity of AD was assessed by the objective severity scoring of AD (SCORing Atopic Dermatitis [SCORAD]). Results: Data analysis showed no statistical difference for the basal serum cortisol levels ( p = .383) and the TAI-C ( p = .730) between the two groups. No significant correlation was found between the basal cortisol values and the TAI-C scores in the AD group ( p = .290). The SCORAD index was correlated with the TAI-C scores ( p < .05) but not correlated with the basal serum cortisol values in AD patients ( p = .06). Conclusion: Children with AD do not have more anxiety or different cortisol levels when compared with normal children, but the severe symptomatology of AD itself may cause anxiety levels to increase in children with AD.


Dermatitis ◽  
2008 ◽  
Vol 19 (4) ◽  
pp. 218-238
Author(s):  
Carla A. F. M. Bruijnzeel-Koomen ◽  
Inge Marjet Haeck ◽  
Linda Timmer-de Mik ◽  
Everardus G. W. M. Lentjes ◽  
Erik Buskens ◽  
...  

2010 ◽  
Vol 88 (2) ◽  
pp. 599-603 ◽  
Author(s):  
D. T. Yates ◽  
T. T. Ross ◽  
D. M. Hallford ◽  
L. J. Yates ◽  
R. L. Wesley

Sign in / Sign up

Export Citation Format

Share Document