scholarly journals Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures

2020 ◽  
Author(s):  
Juan Tornin Cavielles ◽  
Cédric Pierre Labay ◽  
Francesco Tampieri ◽  
Maria Pau Ginebra Molins ◽  
Cristina Canal Barnils
Keyword(s):  
Cancer Cell ◽  
Cell Cultures ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma

scholarly journals Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures

2021 ◽  
Author(s):  
Juan Tornin ◽  
Cédric Labay ◽  
Francesco Tampieri ◽  
Maria-Pau Ginebra ◽  
Cristina Canal
Keyword(s):  
Cancer Cell ◽  
Cell Cultures ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma

scholarly journals Mismatch of frequencies of ac voltage and streamers propagation in cold atmospheric plasma jet for typical regimes of cancer cell treatment

2021 ◽  
Vol 2100 (1) ◽  
pp. 012020
Author(s):  
I Schweigert ◽  
A Alexandrov ◽  
D Zakrevsky ◽  
E Milakhina ◽  
E Patrakova ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cancer Cell ◽  
Plasma Jet ◽  
Plasma Source ◽  
Atmospheric Plasma ◽  
Modes Of Operation ◽  
Cold Atmospheric Plasma ◽  
Mode Of Operation ◽  
Voltage Frequency

Abstract Cold atmospheric plasma (CAP) jet generated by the plasma source at 2-6 kV ac voltages with frequencies of 10-50 kHz demonstrate the different modes of operation. Depending on the voltage frequency and amplitude, some streamers in the plasma jet are short and decay before they approach the treated surface. In this case, the effect on the viability of cancer cells when exposed to CAP jet strongly depends on the mode of operation of the discharge or, in other words, on how many times the streamers hit the bio-target during the treatment. The effect on different modes on cancer cells A549 viability is reported.

scholarly journals NO2-and NO3-enhance cold atmospheric plasma induced cancer cell death by generation of ONOO-

AIP Advances ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. 105219 ◽  
Author(s):  
Dehui Xu ◽  
Qingjie Cui ◽  
Yujing Xu ◽  
Zhijie Liu ◽  
Zeyu Chen ◽  
...  
Keyword(s):  
Cell Death ◽  
Cancer Cell ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma ◽  
Cancer Cell Death

scholarly journals Cold Atmospheric Plasma Induces ATP-Dependent Endocytosis of Nanoparticles and Synergistic U373MG Cancer Cell Death

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Zhonglei He ◽  
Kangze Liu ◽  
Eline Manaloto ◽  
Alan Casey ◽  
George P. Cribaro ◽  
...  
Keyword(s):  
Cell Death ◽  
Cancer Cell ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma ◽  
Cancer Cell Death

Physical and chemical enhancement of cancer cell death induced by cold atmospheric plasma

2021 ◽  
Vol 60 (3) ◽  
pp. 030501
Author(s):  
Mati Ur Rehman ◽  
Paras Jawaid ◽  
Qing-Li Zhao ◽  
Takashi Kondo ◽  
Jun-ichi Saitoh ◽  
...  
Keyword(s):  
Cell Death ◽  
Cancer Cell ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma ◽  
Cancer Cell Death ◽  
Chemical Enhancement ◽  
Physical And Chemical

scholarly journals Cold Atmospheric Plasma Attenuates Breast Cancer Cell Growth Through Regulation of Cell Microenvironment Effectors

2022 ◽  
Vol 11 ◽  
Author(s):  
Christos A. Aggelopoulos ◽  
Anna-Maria Christodoulou ◽  
Myrsini Tachliabouri ◽  
Stauros Meropoulis ◽  
Maria-Elpida Christopoulou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Atmospheric Plasma ◽  
Stem Cell Marker ◽  
Cancer Cell Growth ◽  
Cold Atmospheric Plasma ◽  
Breast Cancer Cell Growth ◽  
The Impact

Breast cancer exists in multiple subtypes some of which still lack a targeted and effective therapy. Cold atmospheric plasma (CAP) has been proposed as an emerging anti-cancer treatment modality. In this study, we investigated the effects of direct and indirect CAP treatment driven by the advantageous nanosecond pulsed discharge on breast cancer cells of different malignant phenotypes and estrogen receptor (ER) status, a major factor in the prognosis and therapeutic management of breast cancer. The main CAP reactive species in liquid (i.e. H2O2, NO2−/NO3−) and gas phase were determined as a function of plasma operational parameters (i.e. treatment time, pulse voltage and frequency), while pre-treatment with the ROS scavenger NAC revealed the impact of ROS in the treatment. CAP treatment induced intense phenotypic changes and apoptosis in both ER+ and ER- cells, which is associated with the mitochondrial pathway as evidenced by the increased Bax/Bcl-2 ratio and cleavage of PARP-1. Interestingly, CAP significantly reduced CD44 protein expression (a major cancer stem cell marker and matrix receptor), while differentially affected the expression of proteases and inflammatory mediators. Collectively, the findings of the present study suggest that CAP suppresses breast cancer cell growth and regulates several effectors of the tumor microenvironment and thus it could represent an efficient therapeutic approach for distinct breast cancer subtypes.

scholarly journals Investigation of Cold Atmospheric Plasma induce Apoptosis in Cancer Cell

2018 ◽  
Vol 1144 ◽  
pp. 012025
Author(s):  
Wasin Nupangtha ◽  
Chakkrapong kuensaen ◽  
Sureeporn Sarapirom ◽  
Dheerawan Boonyawan
Keyword(s):  
Cancer Cell ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma
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