scholarly journals Squamous Cell Carcinoma (SCC) and Chronic Radiation Dermatitis Associated with Childhood Ionizing Radiation Exposure: Case Report with Review of the Literature

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Kai-Lou C. Yue ◽  
Isabelle Lombardi ◽  
Lohit Sodagum ◽  
Dennis Porto

Introduction: Squamous cell carcinoma (SCC) is one of the most common types of skin cancer in Caucasians, but the role played by ionizing radiation (IR) exposure in its etiology is unclear. Case Presentation: This study presents a patient with SCC, actinic keratoses, and radiation dermatitis of the feet with a distant history of IR exposure from a shoe-fitting fluoroscope. It is likely the fluoroscope’s IR contributed to the etiology of these manifestations. Conclusions: Patients with a history of repeated IR exposure, particularly from older, unregulated sources such as a shoe-fitting fluoroscope, should be monitored with a high index of suspicion for skin cancer and other related problems.

Dermatology ◽  
2008 ◽  
Vol 217 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Cristina Renzi ◽  
Simona Mastroeni ◽  
Thomas J. Mannooranparampil ◽  
Francesca Passarelli ◽  
Alessio Caggiati ◽  
...  

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Makama Baje Salihu ◽  
Stephen Yusuf ◽  
Adogu Ibrahim Ogere

Squamous cell carcinoma of the kidney is a rare malignancy of the upper urothelium usually seen at advanced stage due to delay in diagnosis and or presentation. Mostly seen in patients with history of untreated chronic urolithiasis, chronic renal infection or analgesic abuse. A 46-years-old man who presented with right recurrent loin pain that radiates to the right groin of 10 years duration which worsened 2 weeks prior to presentation, he had history of recent haematuria, right loin pain, significant weight lost with associated history of untreated right renal calculi. General examination was not remarkable, ultrasound scan revealed a huge right renal mass with calculi. Intravenous urogram showed a non-functioning right kidney. Right radical nephrectomy was done, cut surface showed replacement of the renal parenchyma with greyish white tumour with stones in some blind calyxes. Histology revealed moderately differentiated squamous cell carcinoma of the right kidney. We report a case of moderately differentiated squamous cell carcinoma of the right kidney in a patient with a long history of untreated renal calculi. High index of suspicion for malignancy should be kept when seeing patients with long history of untreated renal calculi.


2021 ◽  
Vol 14 (1) ◽  
pp. e236477
Author(s):  
Subhash Soni ◽  
Poonam Elhence ◽  
Vaibhav Kumar Varshney ◽  
Sunita Suman

Squamous cell carcinoma (SCC) of the ampulla of Vater is a rare pathology and only few cases are reported in the literature. With limited experience of primary SCC in the ampulla of Vater, its biological behaviour, prognosis and long-term survival rates are not well known. A 38-year-old woman presented with a history of painless progressive jaundice for which self-expending metallic stent was placed 3 years back. She was evaluated and initially diagnosed as probably periampullary adenocarcinoma. She underwent pancreaticoduodenectomy and histopathology with immunohistochemistry was suggestive of SCC of ampulla of Vater. She received adjuvant chemotherapy and doing well with no recurrence after 1 year of follow-up. In conclusion, SCC of the ampulla is an unusual pathology that should be kept as a differential diagnosis for periampullary tumours. Surgical treatment with curative intent should be performed whenever feasible even in the setting of bulky tumour to improve the outcome.


2021 ◽  
pp. 912-917
Author(s):  
Zainub Ajmal ◽  
Abdul Moiz Khan ◽  
Lezah McCarthy ◽  
Allison Lupinetti ◽  
Syed Mehdi

Leiomyosarcoma (LMS) of the trachea is an extremely rare malignancy with only a few reported cases in English literature. As such the diagnosis can be frequently missed or delayed. We present a case of a 69-year-old male who underwent tracheostomy for airway obstruction secondary to glottic squamous cell carcinoma and treated definitely with radiation therapy. Subsequently, the patient developed LMS of the tracheostomy site. The case further details multiple risk factors that could contribute to development of LMS including radiation exposure, prior malignancy, and chronic inflammation. These risk factors have been well established for LMS in other sites but less so in the head and neck region, which is the subject of our discussion. We also review the current guidelines for head and neck as well as limb sarcomas and discussed role of surgery or radiation and their accompanying challenges in management of this rare malignancy.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110330
Author(s):  
Atsushi Musha ◽  
Nobuteru Kubo ◽  
Naoko Okano ◽  
Hidemasa Kawamura ◽  
Yuhei Miyasaka ◽  
...  

A 50-year-old woman with a long history of nasopharyngeal cancer (T2N2M0, squamous cell carcinoma) underwent chemoradiotherapy and surgery. In the past, to prevent tumor recurrence or metastasis, she underwent concurrent chemoradiotherapy or neck dissection. However, during a follow-up 10 years after the surgery, intense F-18 fluorodeoxyglucose uptake was detected in the oral area (SUVmax 6.0). A biopsy of the area with F-18 fluorodeoxyglucose uptake revealed pathological inflammation. Radiography showed the presence of a wisdom tooth, located at the F-18 fluorodeoxyglucose accumulation site, and pericoronitis of this tooth was detected. Our findings indicate the importance of considering the effect of inflammatory conditions, such as periodontal disease, in using F-18 fluorodeoxyglucose positron emission tomography/computed tomography during follow-up after head and neck cancer treatment.


2011 ◽  
Vol 36 (4) ◽  
pp. 384-388 ◽  
Author(s):  
J.-P. Jeannon ◽  
E. Ofu ◽  
A. Balfour ◽  
J. Bowman ◽  
R. Simo

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