scholarly journals Recent Trends of Syndromic Sexually Transmitted Infections at a Tertiary Care Center in Maharashtra, India: A Retrospective Analysis

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Ravindranath Brahmadeo Chavan ◽  
Vasudha Abhijit Belgaumkar ◽  
Nitika S. Deshmukh ◽  
Ranjitha Krishnegowda
Keyword(s):  
Abdominal Pain ◽  
Sexually Transmitted Infections ◽  
Vaginal Discharge ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Genital Ulcer ◽  
Care Hospital ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease

Background: Sexually transmitted infections (STIs) constitute a major public health problem in both developed and developing countries. Human immunodeficiency virus (HIV) and STIs are linked in their similar mode of transmission, with STIs facilitating the acquisition and transmission of HIV. The prevalence pattern of individual STIs may evolve over time necessitating a corresponding change in management strategies. Objectives: The study was conducted to determine the burden and any change in the etiological trend among attendees of an STIs clinic at a tertiary care hospital. Methods: This retrospective study analyzed data retrieved from consecutive patients attending an STIs clinic over two years (July 2018 to July 2020). Results: Overall, 1916 patients were diagnosed with STIs. The predominant age group was 25 - 44 years (59.23%). Genital ulcer disease was the foremost syndrome (1213, 63.3%). Overall, herpetic genital ulcer was the most common (682, 35.6%), followed by non-herpetic ulcers (531, 27.7%). Vaginal discharge, lower abdominal pain, and urethritis were found in 461 (24%), 219 (11.43%), and 23 (1.27%) of the patients, respectively. Amongst 237 (12.36%) In HIV seropositive attendees, genital ulcer disease (herpetic) was the most common syndrome (179, 75.53%), followed by vaginal discharge (42, 17.72%), lower abdominal pain (9, 3.8%), and urethritis (7, 2.9%). Conclusions: A definite change in the profile of STIs was observed with ulcerative STIs (particularly herpes genitalis) constituting the major burden against a discernible back drop of decreasing non-herpetic STIs. A systematic, regional, periodic synopsis would not only help to follow and document the dynamic trends, but also can help to assess the effectiveness of control programs.

scholarly journals Pattern of Sexually Transmitted Infections: A Retrospective Study from a Tertiary Care Hospital in Central India

2021 ◽  
Author(s):  
Sushil Rathi ◽  
Sumit Ashok Hajare ◽  
Saurabh Jaiswal ◽  
Sandip Agrawal ◽  
Abhijit Kherde ◽  
...  
Keyword(s):  
Sexually Transmitted Infections ◽  
Vaginal Discharge ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Care Hospital ◽  
Cross Sectional ◽  
Adequate Treatment ◽  
Major Health ◽  
Sexually Transmitted

Introduction: Sexually Transmitted Infections (STIs) pose a major health, social and economic problem worldwide, predominantly in developing countries like India. It is essential to understand the current patterns of STIs in the various regions of the country in order to plan and implement strategies to control the spread of infection. Aim: To study the pattern of STIs among patients attending the STI clinic. Materials and Methods: This was a cross-sectional study of data obtained retrospectively from case records over last seven years (January 2013-December 2019) from STI clinic at a tertiary care hospital at Nagpur. The demographic details, detailed history, clinical findings were noted and relevant investigations were performed. The patients were diagnosed as per syndromic approach and subjected to serologic tests for syphilis and Human Immunodeficiency Virus (HIV). The data was analysed by using MS Excel and Epi Info software, and percentage, mean, standard deviation and proportions were calculated. Results: Out of the total 4471 cases, 2807 (62.8%) were males and 1664 (37.2%) were females. The most commonly observed STI was balanoposthitis, followed by cervico-vaginal discharge, Genital Ulcerative Disease- Herpetic (GUD-H), anogenital warts, molluscum contagiosum, GUD-nonherpetic, urethral discharge, lower abdominal pain and inguinal bubo. The proportion of viral STIs was 33.5% (1495 cases) and bacterial STIs were 4.3% (191 cases). The most commonly observed STI was balanoposthitis in males and cervico-vaginal discharge in females. Newly diagnosed cases of HIV were 1.4% (61 cases) of total cases. Conclusion: The proportion of viral STIs was higher compared to bacterial STIs. The prevalence of HIV among study population was 3.9%. Since STIs are indicators of high risk sexual behaviour in the community and a major health burden with risk of development of HIV, prompt diagnosis and adequate treatment of STIs is necessary.

scholarly journals Prevalence of sexually transmitted infections in a tertiary care centre of North India

2021 ◽  
Vol 8 (11) ◽  
pp. 5404
Author(s):  
Amarbir Singh Boparai ◽  
Jatinderpal Singh ◽  
B. K. Brar ◽  
Sukhpreet Kaur Gill
Keyword(s):  
Herpes Simplex ◽  
Sexually Transmitted Infections ◽  
Fungal Infections ◽  
Tertiary Care ◽  
North India ◽  
Genital Ulcer ◽  
World Knowledge ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease

Background: Sexually transmitted infections (STI’s) are most common notifiable infectious diseases in the world. Knowledge of prevalence of STI’s is important to implement appropriate control strategies. This study is undertaken to see any changing trends in prevalence of STI’s by comparing with previous studies.Methods: All the patients who attended STI clinic from July 2019 to June 2020 were included in the study. Diagnosis was made on basis of history, clinical examination and laboratory investigations.Results: The 2188 patients were seen from July 2019 to June 2020 in STI clinic. Mean age group of patients is 25-44 years. Scabies (31.6%) was the commonest STI seen in outpatient department followed by balanoposthitis (16.4), vaginal discharge (12.5%), human immunodeficiency virus (HIV) (11.4%), herpetic genital ulcer disease (7.9%), genital warts (5.8%), molluscum contagiosum (2.4%), syphilis (2.4%), urethral discharge (1.7%), non-herpetic genital ulcer disease (0.4%), non-gonococcal urethritis (0.4%).Conclusions: Scabies was the most common STI reported in our study followed by balanoposthitis and vaginal/cervical discharge. Among the viral STI’s, HIV is showing alarmingly rising trends and is most common viral STI seen in the study followed by herpes simplex virus (HSV). May be there is less reporting of genital herpes simplex infection due to its self-resolution. As compared to previous studies, rising trends of fungal infections are seen which can be due to syndromic management of bacterial STI’s, rising incidence of diabetes mellitus as well as illicit use of over-the-counter broad-spectrum antibiotics given by the local practitioners.

scholarly journals Per-vaginal Findings among the Women with Pelvic Inflammatory Diseases at a Tertiary Care Hospital in Dhaka City

2018 ◽  
Vol 8 (2) ◽  
pp. 90-93
Author(s):  
Tahamina Khanum ◽  
Nasima Begum ◽  
Kazi Mobina Akhter
Keyword(s):  
Vaginal Discharge ◽  
Inflammatory Diseases ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Care Hospital ◽  
Perineal Tear ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Cervical Motion ◽  
Cervical Motion Tenderness

Background: Pelvic inflammatory disease (PID) is a major health problem for adult female. Women presented with pelvic inflammatory diseases give different per-vaginal findings. So we designed this study to assess the per-vaginal findings among the women presented with pelvic inflammatory diseases.Objective: The purpose of the present study was to measure the pervaginal findings among the women with PID.Materials and Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynaecology at Dhaka Medical College & Hospital, Dhaka during January to June 2007. Women in the age group of 15−45 years presented with lower abdominal pain, tenderness, per-vaginal discharge and cervical motion tenderness were included in this study. After taking verbal consent from the patients, a pre-designed data collection sheet was filled in after per-vaginal examination.Results: The study was done on 50 cases, of which 20% patients had 1st degree perineal tear, 6% had utero-vaginal prolapse and 24% had foul-smelling vaginal discharge. Majority (90%) patients had healthy vagina. Ninety percent patients had anteverted uterus; and uterus was mobile in 60% cases. Cervical motion tenderness was present in 44% cases, tenderness of fornix was found in 34% cases and thickening of fornix was found in 22%.Conclusion: In this study first degree perineal tear, foul smelling vaginal discharge and cervical motion tenderness are the commonest findings among the women presented with pelvic inflammatory diseases.J Enam Med Col 2018; 8(2): 90-93

scholarly journals VAGINAL DISCHARGE

2011 ◽  
Vol 18 (04) ◽  
pp. 598-603
Author(s):  
SHAHIDA SHAIKH ◽  
SALEEM AKHTER SHAIKH ◽  
INAYAT MAGSI
Keyword(s):  
Vaginal Discharge ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Internally Displaced ◽  
Syndromic Management ◽  
Sexually Transmitted ◽  
Medical College ◽  
Abnormal Growth ◽  
History Of

Objective: To observe the results of syndromic management in women living in IDPs camps complaining of chronic vaginal discharge. Design: Descriptive study. Setting: Medical Camps at Larkana set by Chandka Medical College Hospital for Internally Displaced Persons (IDPs) due to floods. Period: 1st September 2010 to 31st December 2010. Material and Methods: Total 200 symptomatic patients aged from 20 to 50 years suffering from chronic vaginal discharge having history of more than 6 months duration were included in the study. Asymptomatic as well as pregnant women and patients with abnormal cervix and having abnormal growth on cervix were excluded from the study. A detailed history and examination (including speculum and vaginal) was done and a proforma was filled. All these patients were given empirical treatment recommended by WHO as syndromic management consisting of stat doses of antifungal along with antibiotics, where no laboratory tests are required before treatment. Results: Next to vaginal discharge which was main symptom in all patients, the other symptoms like dusparunia, dysuria, itching ,lower abdomen pain and low backache was reported 9%, 16%, 20%, 24% and 31% respectively. Also 8% patients reported post coital bleeding. All patients were married and the mean age of the patients was 28+0.2 years and 15% of them were over 40 years. Mean parity was 4±1.Vaginal infection improved in 65% of the patients excellently with a first line single course of antibiotic and percentage raised up to 88% with second course. 19(9.5%) patients couldn’t be followed as they left that camp and 5(2.5%) patients who did not improve with two courses of antibiotics had big cervical erosions, referred to nearby tertiary care hospital for further management. Conclusions: IDPs live in poor conditions in camps without basic facilities and where it is difficult to perform bedside tests like microscopy, Potassium Hydroxide, wet mount films and tests for Sexually transmitted diseases like Chlamydia and gonorrhea are not available, syndromic management there is a rational way of treating cases of chronic vaginal discharge to get quicker response in such desperate women. 

Etiology of Genital Ulcer Disease in Dakar, Senegal, and Comparison of PCR and Serologic Assays for Detection of Haemophilus ducreyi

2000 ◽  
Vol 38 (1) ◽  
pp. 268-273
Author(s):  
Patricia A. Totten ◽  
Jane M. Kuypers ◽  
Cheng-Yen Chen ◽  
Michelle J. Alfa ◽  
Linda M. Parsons ◽  
...  
Keyword(s):  
Transmitted Disease ◽  
Haemophilus Ducreyi ◽  
Genital Ulcer ◽  
Serological Tests ◽  
Past Infection ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Pcr Assays ◽  
Simplex Virus

ABSTRACT We used PCR assays to determine the etiology of genital ulcers in patients presenting to a sexually transmitted disease clinic in Dakar, Senegal, and evaluated the ability of two PCR tests ( groEL and recD ) and two serological tests (adsorption enzyme immunoassay [EIA] and lipooligosaccharide [LOS] EIA) to detect current Haemophilus ducreyi infection. We found that in this population, H. ducreyi , T. pallidum , and herpes simplex virus HSV DNA were detected in 56, 15, and 13% of 39 genital ulcer specimens, respectively, and H. ducreyi DNA was detected in 60% (3 of 5) of samples from ulcerated bubos. Among 40 consecutive patients with genital ulcer disease and with sufficient sample for both PCR assays, the recD and groEL H. ducreyi PCR assays were 83% concordant, with the recD PCR assay detecting six (15%) additional positive specimens and the groEL assay detecting one (3%) additional positive specimen. Compared to PCR, the adsorption EIA and LOS EIA tests had sensitivities of 71 and 59% and specificities of 57 and 90%, respectively, for the diagnosis of current H. ducreyi infection. While these differences in specificity could be due either to previous infection with H. ducreyi or to the detection of cross-reacting antibodies, only 6% of patients from a nearby family planning clinic gave a positive reaction in both the adsorption EIA and LOS EIA assays, indicating that cross-reacting antibodies are not prevalent among clinic attendees in this city. Our studies indicate that the adsorption EIA detects both current and past infection, while the LOS EIA assay is more specific for current infection with H. ducreyi in this population.

scholarly journals Clinico-Epidemiological Profile of Viral Sexually Transmitted Infections in Seropositive Patients Attending a Tertiary Care Hospital in North India

2017 ◽  
Vol 16 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Shikha Chugh ◽  
Vijay Kumar Garg ◽  
Rashmi Sarkar ◽  
Kabir Sardana
Keyword(s):  
Sexually Transmitted Infections ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Developed Countries ◽  
North India ◽  
Major Public Health Problem ◽  
Care Hospital ◽  
Sexually Transmitted ◽  
Hiv Seropositive

Sexually transmitted diseases are a major public health problem both in developing and in developed countries, and especially with the co-synergy with HIV infection, there is an increasing need to have a proper understanding of the clinicodemographic patterns of sexually transmitted infections (STIs) for planning and implementing control strategies. Worldwide, there is an increased preponderance of viral STIs. Increasing incidence and altered clinical presentation of viral STIs in patients with HIV pose a diagnostic challenge; thereby, we studied the demographic profile of HIV-seropositive patients and compared clinical manifestations of viral STIs in HIV-seropositive patients to those in seronegative individuals. Twenty-seven HIV-seropositive patients with viral STI (herpes/molluscum/warts) and same number of age-, sex-, and STI-matched seronegative patients were studied for variability in clinical profile. There were significant differences in the demographic factors (education, income, and migration) and sexual practices (number of contacts and source of infection) in the 2 groups. Lesional symptoms, increased extent of lesions, and resistance to treatment were significantly more common in HIV-seropositive patients.

scholarly journals Sexually transmitted infections among men who have sex with men: a retrospective study in a tertiary care hospital

2017 ◽  
Vol 5 (7) ◽  
pp. 3222
Author(s):  
Prabahar P. ◽  
Ranganathan T. ◽  
Vijayabhaskar C. ◽  
S. Kalaivani ◽  
Balamurugan L. ◽  
...  
Keyword(s):  
Sexually Transmitted Infections ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Heterosexual Men ◽  
High Risk Population ◽  
Care Hospital ◽  
Serum Samples ◽  
Sexually Transmitted ◽  
Urethral Discharge ◽  
Sex With Men

Background: Men who have sex with Men (MSM) have a higher prevalence of HIV and other sexually transmitted infections (STI) than the heterosexual men. In India, NACP recommendations to reduce HIV prevalence among MSM include early detection of HIV and other STI by screening and treatment. We conducted a study of STIs among MSM attending our OPD. The aim of the study was to assess the prevalence of STIs in MSM attending our OPD.Methods: 1215 MSM among 9008 patients who attended our OPD between June 2015 and May 2016 were included in the study. Detailed history was taken and clinical examination carried out. Urethral discharge and urine samples were tested for Gonococcal infection. Smears from ulcers were tested for Syphilis, Chancroid, Herpes and Donovanosis. Serum samples were tested for HIV and other STIs like Syphilis and Herpes.Results: Among 1215 MSMs, 55 (4.5%) tested positive for VDRL and TPHA and 33 (2.7%) tested positive for HIV. 24 (2%) had urethritis (10 GU and 14 NGU), 15 (1.25%) had Balanophosthitis, 12 (1%) had genital herpes, 9 (0.75%) had genital scabies, 6 (0.5%) had Genital Wart and 2 (0.16%) had Molluscum contagiosum. Prevalence of these STIs were far higher in MSMs than in heterosexual men.Conclusions: This study highlights the higher prevalence of STIs among MSMs and the need for early intervention and treatment in this high-risk population.

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