Molecular Characterization and Distribution of Class 1 Integron-Bearing Methicillin Resistant Staphylococcus aureus Strains in Burn Patients, Tehran, Iran

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Hossein Goudarzi ◽  
Sima Sadat Seyedjavadi ◽  
Edet E Udo ◽  
Elham Beiranvand ◽  
Maryam Fazeli ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Characterization ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Burn Patients ◽  
Class 1 Integron ◽  
Methicillin Resistant ◽  
Class 1

scholarly journals Molecular Characterization of Community-Associated Methicillin-Resistant Staphylococcus aureus in Iranian Burn Patients

2019 ◽  
Vol 14 (4) ◽  
pp. 284-289 ◽  
Author(s):  
Samira Tajik ◽  
Shahin Najar Peerayeh ◽  
Bita Bakhshi ◽  
Reza Golmohammadi
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Characterization ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Significant Proportion ◽  
Burn Patients ◽  
Burn Wound ◽  
Methicillin Resistant ◽  
Pfge Typing ◽  
Mrsa Strains

Background & Objective: Methicillin-resistant Staphylococcus aureus (MRSA) is reported as one of the important bacterial causes of burn wound infections. This study was carried out to investigate molecular characterization of community-associated MRSA (CA-MRSA) isolated from Iranian burn patients. Methods: A total of 31 isolates of S. aureus were collected fromthe Motahari Burns Hospital (Tehran, Iran) in 2016. All isolates were collected from outpatients and inpatients within 48 hours of admission. The mecA, pvl, tsst-1, hla-α, and psmα genes detecting, SCCmec, agr and PFGE typing were done. Results: A total of 13 (41.9%) isolates were cefoxitin-resistant and mecA-positive, which were considered as MRSA. The SCCmec typing MRSA strains revealed type II in 1 (7.7%), type III in 9 (69.2%), and other types in 3 isolates (23.7%) cases. The agrtyping of all 31 isolates showed that 14 (45.2%), 1 (3.2%), 6 (19.4%), and 10 (32.3%) strains belonged to agr groups 1, 3, 4, and unknown type, respectively. The pvl, tsst-1, hla-α, and psmα genes were positive in 3 (9.7%), 4 (12.9%), 21 (67.7%), and 31 (100%) isolates, respectively. Considering the cut-off values of ≥50%, 3 groups of related isolates (cluster A1, B1, and C1) in PFGE study were observed. Conclusion: The MRSA strains of this study were initially isolated as Community-associated S. aureus (CA-MRSA); however molecular characterization showed that a significant proportion of them had hospital-associated MRSA (HA-MRSA) features. Therefore, it is likely that the HA-MRSA strains are spread among the community.

scholarly journals Molecular characterization of the first community-acquired methicillin-resistant Staphylococcus aureus strains from Central Iran

2013 ◽  
Vol 17 (11) ◽  
pp. e949-e954 ◽  
Author(s):  
Alireza Japoni-Nejad ◽  
Mohsen Rezazadeh ◽  
Hamid Kazemian ◽  
Nasimeh Fardmousavi ◽  
Alex van Belkum ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Characterization ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Central Iran ◽  
Methicillin Resistant

Epidemiology and Risk Factors for Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Among Burn Patients

2011 ◽  
Vol 32 (3) ◽  
pp. 429-434 ◽  
Author(s):  
Meghann L. Kaiser ◽  
Deborah J. Thompson ◽  
Darren Malinoski ◽  
Christopher Lane ◽  
Marianne E. Cinat
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Burn Patients ◽  
Methicillin Resistant ◽  
Hospital Acquired
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