The Effects of Raw Red Onion Consumption on Serum Levels of Adiponectin, Leptin, and hs-CRP in Overweight/Obese Females with Polycystic Ovarian Syndrome: A Randomized Controlled-Clinical Trial

2017 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maryam Saghafi-Asl ◽  
Mehranghiz Ebrahimi-Mameghani
Keyword(s):  
Clinical Trial ◽  
Polycystic Ovarian Syndrome ◽  
Serum Levels ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled ◽  
Hs Crp ◽  
Ovarian Syndrome

Effect of Prebiotic on Anthropometric Indices in Women with Polycystic Ovarian Syndrome: A Triple-Blind, Randomized, Controlled Clinical Trial

2018 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sevda Gholizadeh Shamasbi ◽  
Parvin Dehghan ◽  
Sakineh Mohammad-Alizadeh Charandabi ◽  
Akbar Aliasgarzadeh ◽  
Mojgan Mirghafourvand
Keyword(s):  
Clinical Trial ◽  
Polycystic Ovarian Syndrome ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Anthropometric Indices ◽  
Randomized Controlled ◽  
Ovarian Syndrome

scholarly journals Effect of N-acetylcysteine on remission maintenance in patients with ulcerative colitis: A Randomized controlled clinical trial

2020 ◽  
Author(s):  
Kourosh Masnadi Shirazi ◽  
Simin Sotoudeh ◽  
Arman Masnadi Shirazi ◽  
Seyyed-Yaghoub Moaddab ◽  
Zahra Nourpanah ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Clinical Trial ◽  
Placebo Group ◽  
Fecal Calprotectin ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Post Intervention ◽  
Randomized Controlled ◽  
Remission Maintenance ◽  
Hs Crp

Abstract Background: The use of antioxidant agents is suggested as a complementary therapy in UC patients for prevention of flares. Considering the potent antioxidant activity of N-acetylcysteine (NAC), in the present study we aimed to assess the effect of this supplement on remission maintenance in patients with ulcerative colitis (UC). Methods: In the present double-blind randomized controlled clinical trial, 168 volunteer UC patients who were on high dose corticosteroid for flare-up management, were recruited. The patients received 400 mg NAC or placebo twice daily for 16 weeks. Simultaneously, the prednisolone dose was tapered. The patients were followed up six more weeks post-intervention. The primary efficacy of the treatment was remaining in remission. The secondary outcomes were the endoscopic relapse, serum level of hs-CRP, hemoglobin, and fecal calprotectin level. Results: During 22 weeks follow up, 25 patients experienced relapses, six of them were in the NAC group and 19 of them were in the placebo group. There was a significant difference between the NAC and placebo groups regarding the relapse-free period (P=0.007). Compared with the NAC group, significantly more patients in the placebo group had an endoscopic relapse (p <0.001). At the end of the intervention period (16 weeks) and 6 weeks post-intervention, the mean fecal calprotectin, serum erythrocyte sedimentation rate, and hs-CRP levels were significantly lower in the NAC group compared with the placebo group (p<0.05). Conclusion: The findings indicated that NAC had a significantly more positive effect on the maintenance of remission compared with placebo in UC patients that were in the steroid-tapering phase of therapy.

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