Comparing Intravenous Phenylephrine and Ephedrine for Hypotension During Spinal Anesthesia for Elective Cesarean Section: A Randomized Double-Blind Clinical Trial

2017 ◽  
Vol 19 (10) ◽  
Author(s):  
Hedayatollah Vakili ◽  
Hasan Enayati ◽  
Alireza Dashipour
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Elective Cesarean Section ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Elective Cesarean

scholarly journals The impact of mechanical cervical dilatation during elective cesarean section on postpartum scar integrity: a randomized double-blind clinical trial

2019 ◽  
Vol Volume 11 ◽  
pp. 23-29 ◽  
Author(s):  
Ayman Shehata Dawood ◽  
Adel Elgergawy ◽  
Ahmed Elhalwagy ◽  
Waleed M. Ataallah ◽  
Shereen B. Elbohoty ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Cervical Dilatation ◽  
Elective Cesarean Section ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Elective Cesarean ◽  
The Impact

scholarly journals An Investigation Into the Effects of Magnesium Sulfate on the Complications of Succinylcholine Administration in Nulliparous Women Undergoing Elective Cesarean Section: A Double-Blind Clinical Trial

2019 ◽  
Vol 7 (4) ◽  
pp. 520-525
Author(s):  
Davoud Aghamohamadi ◽  
Mehdi Khanbabayi Gol
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Magnesium Sulfate ◽  
Statistical Tests ◽  
Elective Cesarean Section ◽  
Double Blind ◽  
Nulliparous Women ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Elective Cesarean

Objectives: Controlling the complications of anesthetics (e.g., succinylcholine) seems necessary since they are greater for nulliparous women who undergo elective cesarean section (C-section). The present study aimed to investigate the effects of magnesium sulfate on the complications of succinylcholine administration in nulliparous women undergoing elective C-section. Materials and Methods: This double-blind clinical trial was conducted on 60 nulliparous women during 2012-2013. The women were randomly assigned to A and B groups. Before inducing the rapid anesthesia with succinylcholine, patients in the intervention group received 30 mg/kg of magnesium sulfate within 10 minutes and then the hemodynamic status and the side effects of succinylcholine were recorded in a special form. Statistical tests were performed using repeated-measures ANOVA, chi-square test, and one-way ANOVA tests and the level of significance was determined to be P<0.05. Results: There was no significant difference between the two groups in terms of demographic data (P>0.059). However, the results indicated that there was a significant difference between the 2 groups regarding the myoglobin level (P=0.010). Contrarily, the results showed that most patients in the intervention (n=23) and control (n=15) groups experienced no or mild and severe fasciculation, respectively (P<0.001). Conclusions: In general, magnesium sulfate can greatly control and reduce the complications of succinylcholine administration, including fasciculation.

scholarly journals Spinal anesthesia for elective cesarean section. Bupivacaine associated with different doses of fentanyl. Randomized clinical trial

2021 ◽  
Author(s):  
Wesla Packer Pfeifer Ferrarezi ◽  
Angélica de Fátima de Assunção Braga ◽  
Valdir Batista Ferreira ◽  
Sara Quinta Mendes ◽  
Maria José Nascimento Brandão ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Randomized Clinical Trial ◽  
Elective Cesarean Section ◽  
Elective Cesarean ◽  
Different Doses

Effect of Ondansetron on Blood Pressure during Elective Cesarean Section under Spinal Anesthesia at Baghdad Teaching Hospital

2021 ◽  
Vol 1 ◽  
pp. 36-41
Author(s):  
Mustafa Adnan Abdalrahman ◽  
Hassan Mohammed Abbas ◽  
Iyad Abbas Salman
Keyword(s):  
Placebo Group ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Teaching Hospital ◽  
Vital Signs ◽  
Elective Cesarean Section ◽  
Double Blind ◽  
Severe Hypotension ◽  
Medical City ◽  
Elective Cesarean

Background: Hypotension is a very common consequence of the sympathetic vasomotor block caused by spinal anesthesia for caesarean section. Maternal symptoms such as nausea, vomiting and dyspnea frequently accompany severe hypotension, and adverse effects on the fetus, including depressed Apgar scores and umbilical acidosis, have been correlated with severity and duration of hypotension. Aim: To investigate the effect of Ondansetron use on the prevention of hypotension and the amount of vasopressor needed to control the hypotension after spinal anesthesia. Methods: This is a prospective double blind, randomized trial carried out in Obstetric Operation room of Baghdad Teaching Hospital, Medical city, Iraq from November, 2018 to August, 2019. Total number of 128 women assessed for eligibility and only 87 were included and allocated into 2 groups. The Ondansetron group (45 women) received 6 mg Ondansetron IV e min before induction of spinal anesthesia. The Placebo group received 3 ml normal saline as placebo before induction. The number of rescue drugs (vasopressors, antiemetic, anti-shivering), vital signs and side effects were recorded each 3 minutes from baseline to 45th minute. Results: The incidence of hypotension, nausea, vomiting and the need for vasopressors and metoclopramide were significantly lower in Ondansetron group than placebo group (p = 0.001, 0.02, 0.003, < 0.001, and 0.001, respectively). Shivering and the need of pethidine for treating this side effect was non significantly lower in ondansetron group than placebo group. Conclusions: The preoperative administration of Ondansetron in cesarean section reduces the risk of spinal anesthesia-induced hypotension, prevents the nausea and vomiting attacks and decreases the need to vasopressors and metoclopramide. Keywords: Spinal anesthesia, caesarian section, ondansetron, hypotension

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